(25 nodes) Autophagosome maturation network (Cynoglossus semilaevis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103392887	Tectonin beta-propeller repeat containing 1b. (1195 aa)
	LOC103397105	Uncharacterized protein; Belongs to the AAA ATPase family. (806 aa)
	vps16	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (834 aa)
	ENSCSEP00000010047	Microtubule-associated protein 1 light chain 3 beta. (156 aa)
	ENSCSEP00000009170	Uncharacterized protein. (110 aa)
	LOC103382351	Tectonin beta-propeller repeat containing 1a. (1181 aa)
	pik3r4	Phosphoinositide-3-kinase, regulatory subunit 4. (1327 aa)
	map1lc3c	Microtubule-associated protein 1 light chain 3 gamma. (130 aa)
	Stx17	Uncharacterized protein. (64 aa)
	ENSCSEP00000002200	t-SNARE coiled-coil homology domain-containing protein. (176 aa)
	ENSCSEP00000003207	Lysosomal-associated membrane protein 2. (452 aa)
	SNX14	Sorting nexin 14. (940 aa)
	pik3c3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (932 aa)
	ENSCSEP00000009162	Sorting nexin 14. (456 aa)
	map1lc3a	Microtubule-associated protein 1 light chain 3 alpha. (138 aa)
	snap29	Synaptosome associated protein 29. (262 aa)
	vps33a	VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family. (600 aa)
	snapin	SNAP associated protein. (129 aa)
	LIX1L	Limb and CNS expressed 1 like. (361 aa)
	LOC103398190	Limb and CNS expressed 1. (306 aa)
	epg5	Ectopic P-granules autophagy protein 5 homolog (C. elegans). (2583 aa)
	LOC103397425	Vesicle-associated membrane protein 8 (endobrevin). (122 aa)
	LOC103398200	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	uvrag	UV radiation resistance associated gene. (739 aa)
	atg14	Autophagy related 14. (495 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCSEP00000002200	LOC103397105	ENSCSEP00000002200	ENSCSEP00000018351	t-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.405
ENSCSEP00000002200	LOC103397425	ENSCSEP00000002200	ENSCSEP00000021105	t-SNARE coiled-coil homology domain-containing protein.	Vesicle-associated membrane protein 8 (endobrevin).	0.921
ENSCSEP00000002200	LOC103398200	ENSCSEP00000002200	ENSCSEP00000021019	t-SNARE coiled-coil homology domain-containing protein.	Valosin containing protein; Belongs to the AAA ATPase family.	0.405
ENSCSEP00000002200	atg14	ENSCSEP00000002200	ENSCSEP00000019334	t-SNARE coiled-coil homology domain-containing protein.	Autophagy related 14.	0.672
ENSCSEP00000002200	epg5	ENSCSEP00000002200	ENSCSEP00000022190	t-SNARE coiled-coil homology domain-containing protein.	Ectopic P-granules autophagy protein 5 homolog (C. elegans).	0.478
ENSCSEP00000002200	pik3c3	ENSCSEP00000002200	ENSCSEP00000006357	t-SNARE coiled-coil homology domain-containing protein.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.528
ENSCSEP00000002200	pik3r4	ENSCSEP00000002200	ENSCSEP00000001654	t-SNARE coiled-coil homology domain-containing protein.	Phosphoinositide-3-kinase, regulatory subunit 4.	0.487
ENSCSEP00000002200	snap29	ENSCSEP00000002200	ENSCSEP00000031052	t-SNARE coiled-coil homology domain-containing protein.	Synaptosome associated protein 29.	0.921
ENSCSEP00000002200	uvrag	ENSCSEP00000002200	ENSCSEP00000020390	t-SNARE coiled-coil homology domain-containing protein.	UV radiation resistance associated gene.	0.495
ENSCSEP00000002200	vps16	ENSCSEP00000002200	ENSCSEP00000013625	t-SNARE coiled-coil homology domain-containing protein.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.803
ENSCSEP00000002200	vps33a	ENSCSEP00000002200	ENSCSEP00000026328	t-SNARE coiled-coil homology domain-containing protein.	VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family.	0.678
ENSCSEP00000010047	atg14	ENSCSEP00000010047	ENSCSEP00000019334	Microtubule-associated protein 1 light chain 3 beta.	Autophagy related 14.	0.734
ENSCSEP00000010047	map1lc3c	ENSCSEP00000010047	ENSCSEP00000001664	Microtubule-associated protein 1 light chain 3 beta.	Microtubule-associated protein 1 light chain 3 gamma.	0.497
ENSCSEP00000010047	pik3c3	ENSCSEP00000010047	ENSCSEP00000006357	Microtubule-associated protein 1 light chain 3 beta.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.763
ENSCSEP00000010047	pik3r4	ENSCSEP00000010047	ENSCSEP00000001654	Microtubule-associated protein 1 light chain 3 beta.	Phosphoinositide-3-kinase, regulatory subunit 4.	0.728
ENSCSEP00000010047	uvrag	ENSCSEP00000010047	ENSCSEP00000020390	Microtubule-associated protein 1 light chain 3 beta.	UV radiation resistance associated gene.	0.620
LOC103397105	ENSCSEP00000002200	ENSCSEP00000018351	ENSCSEP00000002200	Uncharacterized protein; Belongs to the AAA ATPase family.	t-SNARE coiled-coil homology domain-containing protein.	0.405
LOC103397105	LOC103398200	ENSCSEP00000018351	ENSCSEP00000021019	Uncharacterized protein; Belongs to the AAA ATPase family.	Valosin containing protein; Belongs to the AAA ATPase family.	0.900
LOC103397105	Stx17	ENSCSEP00000018351	ENSCSEP00000002195	Uncharacterized protein; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.405
LOC103397425	ENSCSEP00000002200	ENSCSEP00000021105	ENSCSEP00000002200	Vesicle-associated membrane protein 8 (endobrevin).	t-SNARE coiled-coil homology domain-containing protein.	0.921