STRINGSTRING
tmem258 tmem258 pigu pigu LOC103384526 LOC103384526 pdia3 pdia3 Insig1 Insig1 ENSCSEP00000001648 ENSCSEP00000001648 sec61b sec61b LOC103388194 LOC103388194 ext2 ext2 ppib ppib srpra srpra nbas nbas emc3 emc3 sec63 sec63 piga piga map3k5 map3k5 emc7 emc7 ddost ddost pigc pigc ENSCSEP00000007224 ENSCSEP00000007224 spcs1 spcs1 rpn1 rpn1 sec61a1 sec61a1 pigt pigt spcs2 spcs2 ganab ganab ENSCSEP00000011676 ENSCSEP00000011676 ostc ostc ENSCSEP00000011649 ENSCSEP00000011649 krtcap2 krtcap2 ENSCSEP00000012478 ENSCSEP00000012478 ENSCSEP00000012483 ENSCSEP00000012483 ENSCSEP00000013672 ENSCSEP00000013672 ENSCSEP00000013695 ENSCSEP00000013695 ENSCSEP00000013699 ENSCSEP00000013699 zw10 zw10 emc2 emc2 derl2 derl2 alg14 alg14 sptlc1 sptlc1 pigs pigs gpaa1 gpaa1 sptssa sptssa pdia4 pdia4 derl1 derl1 amfr amfr LOC103397105 LOC103397105 emc10 emc10 LOC103384100 LOC103384100 LOC103388881 LOC103388881 stt3a stt3a pigm pigm LOC103398200 LOC103398200 abcb9 abcb9 Syvn1 Syvn1 fam167a fam167a LOC103388956 LOC103388956 get3 get3 LOC103393011 LOC103393011 emc8 emc8 LOC103394298 LOC103394298 LOC103381859 LOC103381859 spcs3 spcs3 emc6 emc6 ormdl1 ormdl1 rint1 rint1 ubxn7 ubxn7 aup1 aup1 camlg camlg ENSCSEP00000026740 ENSCSEP00000026740 srprb srprb mmgt1 mmgt1 hspa5 hspa5 emc4 emc4 LOC103394399 LOC103394399 Sptssb Sptssb rnf139 rnf139 dad1 dad1 ost4 ost4 hm13 hm13 Dpm2 Dpm2 ENSCSEP00000029925 ENSCSEP00000029925 LOC103398999 LOC103398999 sel1l sel1l ENSCSEP00000030190 ENSCSEP00000030190 emc1 emc1 pigh pigh LOC103393837 LOC103393837 hyou1 hyou1 ufd1 ufd1 faf1 faf1 faf2 faf2 ENSCSEP00000031700 ENSCSEP00000031700 LOC103391437 LOC103391437 ENSCSEP00000032627 ENSCSEP00000032627 pigk pigk PIGY PIGY ormdl2 ormdl2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tmem258Transmembrane protein 258. (79 aa)
piguPhosphatidylinositol glycan anchor biosynthesis, class U. (478 aa)
LOC103384526ER membrane protein complex subunit 3; Belongs to the EMC3 family. (261 aa)
pdia3Protein disulfide-isomerase. (526 aa)
Insig1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. (310 aa)
ENSCSEP00000001648ER membrane protein complex subunit 9. (116 aa)
sec61bProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (94 aa)
LOC103388194Nibrin. (763 aa)
ext2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (719 aa)
ppibPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
srpraSRP receptor subunit alpha. (651 aa)
nbasNeuroblastoma amplified sequence. (2241 aa)
emc3ER membrane protein complex subunit 3; Belongs to the EMC3 family. (261 aa)
sec63SEC63 homolog, protein translocation regulator. (758 aa)
pigaPhosphatidylinositol glycan anchor biosynthesis, class A. (479 aa)
map3k5Mitogen-activated protein kinase kinase kinase 5. (1389 aa)
emc7ER membrane protein complex subunit 7. (248 aa)
ddostDolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] (466 aa)
pigcPhosphatidylinositol glycan anchor biosynthesis, class C. (294 aa)
ENSCSEP00000007224Family with sequence similarity 8 member A1b. (332 aa)
spcs1Signal peptidase complex subunit 1. (159 aa)
rpn1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (601 aa)
sec61a1SEC61 translocon alpha 1 subunit. (476 aa)
pigtPhosphatidylinositol glycan anchor biosynthesis, class T. (654 aa)
spcs2Signal peptidase complex subunit 2. (212 aa)
ganabGlucosidase, alpha; neutral AB; Belongs to the glycosyl hydrolase 31 family. (841 aa)
ENSCSEP00000011676Thioredoxin domain-containing protein; Belongs to the protein disulfide isomerase family. (118 aa)
ostcOligosaccharyltransferase complex subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All s [...] (149 aa)
ENSCSEP00000011649Thioredoxin domain-containing protein; Belongs to the protein disulfide isomerase family. (135 aa)
krtcap2Keratinocyte associated protein 2. (105 aa)
ENSCSEP00000012478Uncharacterized protein. (85 aa)
ENSCSEP00000012483Ig-like domain-containing protein. (91 aa)
ENSCSEP00000013672Selenoprotein S. (145 aa)
ENSCSEP00000013695Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (662 aa)
ENSCSEP00000013699Phosphatidylinositol glycan anchor biosynthesis, class Q. (553 aa)
zw10Zw10 kinetochore protein. (765 aa)
emc2ER membrane protein complex subunit 2. (297 aa)
derl2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
alg14ALG14 UDP-N-acetylglucosaminyltransferase subunit. (215 aa)
sptlc1Serine palmitoyltransferase, long chain base subunit 1. (472 aa)
pigsPhosphatidylinositol glycan anchor biosynthesis, class S. (597 aa)
gpaa1Glycosylphosphatidylinositol anchor attachment 1. (614 aa)
sptssaSerine palmitoyltransferase, small subunit A. (91 aa)
pdia4Protein disulfide-isomerase. (651 aa)
derl1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (254 aa)
amfrAutocrine motility factor receptor b. (600 aa)
LOC103397105Uncharacterized protein; Belongs to the AAA ATPase family. (806 aa)
emc10ER membrane protein complex subunit 10. (257 aa)
LOC103384100Tumor suppressor candidate 3. (292 aa)
LOC103388881STT3 oligosaccharyltransferase complex catalytic subunit B. (819 aa)
stt3aSTT3 oligosaccharyltransferase complex catalytic subunit A. (705 aa)
pigmGPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. (386 aa)
LOC103398200Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
abcb9ATP-binding cassette, sub-family B (MDR/TAP), member 9. (800 aa)
Syvn1Uncharacterized protein. (144 aa)
fam167aFamily with sequence similarity 167 member Ab. (219 aa)
LOC103388956Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP). (735 aa)
get3ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] (341 aa)
LOC103393011Endoplasmic reticulum to nucleus signaling 1. (1036 aa)
emc8ER membrane protein complex subunit 8. (207 aa)
LOC103394298STT3 oligosaccharyltransferase complex catalytic subunit B. (805 aa)
LOC103381859ORMDL sphingolipid biosynthesis regulator 3. (225 aa)
spcs3Signal peptidase complex subunit 3. (180 aa)
emc6ER membrane protein complex subunit 6. (110 aa)
ormdl1ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
rint1RAD50 interactor 1. (795 aa)
ubxn7UBX domain protein 7. (539 aa)
aup1AUP1 lipid droplet regulating VLDL assembly factor. (416 aa)
camlgCalcium modulating ligand. (284 aa)
ENSCSEP00000026740Transporter associated with antigen processing, subunit type t, teleost specific. (678 aa)
srprbSRP receptor subunit beta. (275 aa)
mmgt1Membrane magnesium transporter 1. (151 aa)
hspa5Heat shock protein 5; Belongs to the heat shock protein 70 family. (655 aa)
emc4ER membrane protein complex subunit 4; Belongs to the EMC4 family. (190 aa)
LOC103394399Family with sequence similarity 8 member A1a. (304 aa)
SptssbSerine palmitoyltransferase, small subunit B. (77 aa)
rnf139Ring finger protein 139. (627 aa)
dad1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (113 aa)
ost4Oligosaccharyltransferase complex subunit 4 (non-catalytic). (37 aa)
hm13Histocompatibility (minor) 13. (383 aa)
Dpm2Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (84 aa)
ENSCSEP00000029925Ig-like domain-containing protein. (106 aa)
LOC103398999Ubiquitin recognition factor in ER associated degradation 1. (311 aa)
sel1lSEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (858 aa)
ENSCSEP00000030190Uncharacterized protein. (87 aa)
emc1ER membrane protein complex subunit 1. (908 aa)
pighPhosphatidylinositol glycan anchor biosynthesis, class H. (181 aa)
LOC103393837Transporter associated with antigen processing, subunit type a. (724 aa)
hyou1Hypoxia up-regulated 1. (1020 aa)
ufd1Uncharacterized protein. (297 aa)
faf1Fas (TNFRSF6) associated factor 1. (670 aa)
faf2Fas associated factor family member 2. (501 aa)
ENSCSEP00000031700Protein kinase domain-containing protein. (385 aa)
LOC103391437Magnesium transporter 1. (328 aa)
ENSCSEP00000032627Endoplasmic reticulum to nucleus signaling 2. (954 aa)
pigkGPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (384 aa)
PIGYPhosphatidylinositol glycan anchor biosynthesis class Y. (70 aa)
ormdl2ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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