STRINGSTRING
LOC103385580 LOC103385580 adi1 adi1 LOC103380525 LOC103380525 tmed8 tmed8 LOC103389253 LOC103389253 ENSCSEP00000002406 ENSCSEP00000002406 ilvbl ilvbl pycr3 pycr3 Mtr Mtr mtap mtap apip apip LOC103391608 LOC103391608 LOC103384714 LOC103384714 LOC103399977 LOC103399977 otc otc pah pah LOC103383681 LOC103383681 mthfr mthfr LOC103389519 LOC103389519 sephs1 sephs1 shmt1 shmt1 got1 got1 asns asns psat1 psat1 cth cth psph psph ENSCSEP00000016415 ENSCSEP00000016415 ENSCSEP00000016629 ENSCSEP00000016629 enoph1 enoph1 shmt2 shmt2 LOC103392838 LOC103392838 mri1 mri1 phgdh phgdh ENSCSEP00000019051 ENSCSEP00000019051 LOC103382935 LOC103382935 ALDH18A1 ALDH18A1 nags nags LOC103381768 LOC103381768 LOC103390007 LOC103390007 dhfr dhfr LOC103384353 LOC103384353 LOC103392402 LOC103392402 SDS SDS asnsd1 asnsd1 oat oat ASS1 ASS1 glul glul aasdhppt aasdhppt LOC103397629 LOC103397629 asl asl LOC103389196 LOC103389196 Agxt2 Agxt2 GOT1 GOT1 ENSCSEP00000033939 ENSCSEP00000033939 ENSCSEP00000033941 ENSCSEP00000033941
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103385580Glutaminase 2a (liver, mitochondrial). (510 aa)
adi11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (196 aa)
LOC103380525Serine dehydratase-like. (328 aa)
tmed8Transmembrane p24 trafficking protein 8. (283 aa)
LOC103389253Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (584 aa)
ENSCSEP00000002406Aminoadipate-semialdehyde synthase. (882 aa)
ilvblIlvB (bacterial acetolactate synthase)-like; Belongs to the TPP enzyme family. (625 aa)
pycr3Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (431 aa)
MtrMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1235 aa)
mtapS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (284 aa)
apipMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis. (253 aa)
LOC103391608Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (565 aa)
LOC103384714Selenophosphate synthetase 2. (337 aa)
LOC103399977Zgc:172121; Involved in the regulation of homocysteine metabolism. (326 aa)
otcOrnithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (351 aa)
pahPhenylalanine hydroxylase. (460 aa)
LOC103383681Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (369 aa)
mthfrMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (655 aa)
LOC103389519Glutaminase a. (626 aa)
sephs1Selenophosphate synthetase 1. (392 aa)
shmt1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (466 aa)
got1Aspartate aminotransferase. (410 aa)
asnsAsparagine synthetase [glutamine-hydrolyzing]. (561 aa)
psat1Phosphoserine aminotransferase. (489 aa)
cthCystathionase (cystathionine gamma-lyase), like. (409 aa)
psphPhosphoserine phosphatase. (273 aa)
ENSCSEP00000016415PALP domain-containing protein. (504 aa)
ENSCSEP000000166295-methyltetrahydrofolate-homocysteine methyltransferase reductase. (670 aa)
enoph1Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (261 aa)
shmt2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (501 aa)
LOC103392838Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (318 aa)
mri1Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (353 aa)
phgdhD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (529 aa)
ENSCSEP00000019051Aminotran_1_2 domain-containing protein. (269 aa)
LOC103382935Si:ch73-263o4.3. (320 aa)
ALDH18A1Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (779 aa)
nagsN-acetylglutamate synthase. (415 aa)
LOC103381768Threonine aldolase 1. (411 aa)
LOC103390007Betaine-homocysteine methyltransferase; Involved in the regulation of homocysteine metabolism. (399 aa)
dhfrDihydrofolate reductase. (189 aa)
LOC103384353Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (322 aa)
LOC103392402ANK_REP_REGION domain-containing protein. (595 aa)
SDSSerine dehydratase. (219 aa)
asnsd1Asparagine synthetase domain containing 1. (598 aa)
oatOrnithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa)
ASS1Argininosuccinate synthase 1. (436 aa)
glulGlutamine synthetase. (371 aa)
aasdhpptAminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase. (319 aa)
LOC103397629Hcy-binding domain-containing protein. (413 aa)
aslArgininosuccinate lyase. (472 aa)
LOC103389196Glutamine synthetase. (370 aa)
Agxt2Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (474 aa)
GOT1Aspartate aminotransferase. (410 aa)
ENSCSEP00000033939EF-hand_14 domain-containing protein. (235 aa)
ENSCSEP00000033941Uncharacterized protein. (153 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.