62 items (Cynoglossus semilaevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	trh	Thyrotropin-releasing hormone. (276 aa)
	LOC103385603	RAP1A, member of RAS oncogene family a. (185 aa)
	ENSCSEP00000033038	Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family. (380 aa)
	rhbdf1	Rhomboid 5 homolog 1a (Drosophila). (781 aa)
	ENSCSEP00000032874	Uncharacterized protein. (122 aa)
	LOC103391449	RAB33B, member RAS oncogene family a. (233 aa)
	ENSCSEP00000031689	Interleukin 1 receptor accessory protein-like 2. (611 aa)
	LOC103382067	Rhomboid 5 homolog 1b (Drosophila). (927 aa)
	ENSCSEP00000031239	Uncharacterized protein. (379 aa)
	il12b	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (347 aa)
	IL12B	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (312 aa)
	stxbp3	Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (591 aa)
	ENSCSEP00000030129	Chromogranin A. (274 aa)
	LOC103386699	Uncharacterized protein. (185 aa)
	LOC103396235	Uncharacterized protein. (137 aa)
	LOC103397625	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (347 aa)
	LOC103387817	Interleukin 11a. (200 aa)
	LOC103378493	RAB guanine nucleotide exchange factor (GEF) 1, like. (508 aa)
	LOC103391350	Uncharacterized protein. (230 aa)
	drd3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (457 aa)
	ENSCSEP00000026528	V-SNARE coiled-coil homology domain-containing protein. (97 aa)
	ENSCSEP00000026160	Uncharacterized protein. (86 aa)
	syt4	Synaptotagmin IV. (470 aa)
	fmr1	Fragile X mental retardation 1. (581 aa)
	Rabgef1	RAB guanine nucleotide exchange factor (GEF) 1. (498 aa)
	LOC103383284-2	RAB11 family interacting protein 5a (class I). (1263 aa)
	LOC103389012	Apolipoprotein Eb. (346 aa)
	psmd9	Proteasome 26S subunit, non-ATPase 9. (212 aa)
	LOC107989993	LPXRFa peptide. (194 aa)
	ENSCSEP00000022578	Uncharacterized protein. (1073 aa)
	LOC103395951	Ubiquitin-like domain-containing protein. (450 aa)
	LOC103392309	PNKD metallo-beta-lactamase domain containing. (358 aa)
	crhbp	Corticotropin releasing hormone binding protein. (360 aa)
	LOC103397425	Vesicle-associated membrane protein 8 (endobrevin). (122 aa)
	pim3	Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (316 aa)
	ENSCSEP00000017932	Uncharacterized protein. (133 aa)
	hrh4	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (373 aa)
	LOC103389709	Uncharacterized protein. (733 aa)
	LOC103389902	3-hydroxy-3-methylglutaryl coenzyme A reductase. (873 aa)
	ENSCSEP00000017589	NADH:ubiquinone oxidoreductase complex assembly factor 2. (128 aa)
	LOC103379329	C2 domain-containing protein. (501 aa)
	LOC103380356	Potassium inwardly-rectifying channel, subfamily J, member 11. (381 aa)
	hmgcr	3-hydroxy-3-methylglutaryl coenzyme A reductase. (883 aa)
	RHBDF2	Rhomboid 5 homolog 2. (832 aa)
	sergef	Secretion regulating guanine nucleotide exchange factor. (377 aa)
	LOC103391909	Kruppel-like factor 7b. (310 aa)
	LOC103378863	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (398 aa)
	KLF7	Kruppel like factor 7. (301 aa)
	vamp3	V-SNARE coiled-coil homology domain-containing protein. (117 aa)
	il1rapl1	Interleukin 1 receptor accessory protein-like 1a. (715 aa)
	LOC103381269	CRF domain-containing protein. (145 aa)
	LOC103380098	Leptin A. (160 aa)
	LOC103382506	Uncharacterized protein. (184 aa)
	prkn	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (447 aa)
	CCN3	Cellular communication network factor 3. (352 aa)
	LOC103382441	Potassium inwardly-rectifying channel, subfamily J, member 8. (421 aa)
	Nf1	Neurofibromin 1b. (2702 aa)
	cbarp	CACN subunit beta associated regulatory protein b. (903 aa)
	LOC103399907	Midnolin. (544 aa)
	sirt4	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (365 aa)
	syt11	Synaptotagmin XIb. (465 aa)
	LOC103389249	Zgc:172122. (384 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCSEP00000026528	LOC103379329	ENSCSEP00000026528	ENSCSEP00000017201	V-SNARE coiled-coil homology domain-containing protein.	C2 domain-containing protein.	0.616
ENSCSEP00000026528	LOC103397425	ENSCSEP00000026528	ENSCSEP00000021105	V-SNARE coiled-coil homology domain-containing protein.	Vesicle-associated membrane protein 8 (endobrevin).	0.630
ENSCSEP00000026528	stxbp3	ENSCSEP00000026528	ENSCSEP00000030358	V-SNARE coiled-coil homology domain-containing protein.	Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family.	0.690
ENSCSEP00000026528	syt11	ENSCSEP00000026528	ENSCSEP00000001957	V-SNARE coiled-coil homology domain-containing protein.	Synaptotagmin XIb.	0.616
ENSCSEP00000026528	syt4	ENSCSEP00000026528	ENSCSEP00000025811	V-SNARE coiled-coil homology domain-containing protein.	Synaptotagmin IV.	0.616
ENSCSEP00000033038	drd3	ENSCSEP00000033038	ENSCSEP00000026695	Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.643
IL12B	il12b	ENSCSEP00000031110	ENSCSEP00000031205	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily.	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily.	0.905
LOC103378493	Rabgef1	ENSCSEP00000028169	ENSCSEP00000025510	RAB guanine nucleotide exchange factor (GEF) 1, like.	RAB guanine nucleotide exchange factor (GEF) 1.	0.570
LOC103378493	sergef	ENSCSEP00000028169	ENSCSEP00000009933	RAB guanine nucleotide exchange factor (GEF) 1, like.	Secretion regulating guanine nucleotide exchange factor.	0.414
LOC103378863	drd3	ENSCSEP00000009209	ENSCSEP00000026695	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.643
LOC103379329	ENSCSEP00000026528	ENSCSEP00000017201	ENSCSEP00000026528	C2 domain-containing protein.	V-SNARE coiled-coil homology domain-containing protein.	0.616
LOC103379329	LOC103397425	ENSCSEP00000017201	ENSCSEP00000021105	C2 domain-containing protein.	Vesicle-associated membrane protein 8 (endobrevin).	0.591
LOC103379329	vamp3	ENSCSEP00000017201	ENSCSEP00000007720	C2 domain-containing protein.	V-SNARE coiled-coil homology domain-containing protein.	0.616
LOC103380098	LOC107989993	ENSCSEP00000006517	ENSCSEP00000022640	Leptin A.	LPXRFa peptide.	0.650
LOC103380098	trh	ENSCSEP00000006517	ENSCSEP00000033172	Leptin A.	Thyrotropin-releasing hormone.	0.571
LOC103380356	sergef	ENSCSEP00000014006	ENSCSEP00000009933	Potassium inwardly-rectifying channel, subfamily J, member 11.	Secretion regulating guanine nucleotide exchange factor.	0.541
LOC103381269	LOC103397625	ENSCSEP00000007046	ENSCSEP00000029238	CRF domain-containing protein.	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	0.833
LOC103381269	crhbp	ENSCSEP00000007046	ENSCSEP00000021177	CRF domain-containing protein.	Corticotropin releasing hormone binding protein.	0.750
LOC103382441	sergef	ENSCSEP00000005244	ENSCSEP00000009933	Potassium inwardly-rectifying channel, subfamily J, member 8.	Secretion regulating guanine nucleotide exchange factor.	0.417
LOC103382506	LOC103385603	ENSCSEP00000006488	ENSCSEP00000033583	Uncharacterized protein.	RAP1A, member of RAS oncogene family a.	0.900