9 items (Cynoglossus semilaevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	derl2	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
	derl1	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (254 aa)
	sel1l	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (858 aa)
	LOC103394399	Family with sequence similarity 8 member A1a. (304 aa)
	aup1	AUP1 lipid droplet regulating VLDL assembly factor. (416 aa)
	Syvn1	Uncharacterized protein. (144 aa)
	LOC103398618	Uncharacterized protein. (303 aa)
	ENSCSEP00000007224	Family with sequence similarity 8 member A1b. (332 aa)
	rhbdd2	Rhomboid domain-containing protein. (322 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCSEP00000007224	Syvn1	ENSCSEP00000007224	ENSCSEP00000021423	Family with sequence similarity 8 member A1b.	Uncharacterized protein.	0.539
ENSCSEP00000007224	sel1l	ENSCSEP00000007224	ENSCSEP00000030105	Family with sequence similarity 8 member A1b.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.596
LOC103394399	Syvn1	ENSCSEP00000027608	ENSCSEP00000021423	Family with sequence similarity 8 member A1a.	Uncharacterized protein.	0.539
LOC103394399	sel1l	ENSCSEP00000027608	ENSCSEP00000030105	Family with sequence similarity 8 member A1a.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.596
LOC103398618	rhbdd2	ENSCSEP00000019171	ENSCSEP00000012345	Uncharacterized protein.	Rhomboid domain-containing protein.	0.577
Syvn1	ENSCSEP00000007224	ENSCSEP00000021423	ENSCSEP00000007224	Uncharacterized protein.	Family with sequence similarity 8 member A1b.	0.539
Syvn1	LOC103394399	ENSCSEP00000021423	ENSCSEP00000027608	Uncharacterized protein.	Family with sequence similarity 8 member A1a.	0.539
Syvn1	aup1	ENSCSEP00000021423	ENSCSEP00000026522	Uncharacterized protein.	AUP1 lipid droplet regulating VLDL assembly factor.	0.588
Syvn1	derl1	ENSCSEP00000021423	ENSCSEP00000017906	Uncharacterized protein.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.969
Syvn1	derl2	ENSCSEP00000021423	ENSCSEP00000014619	Uncharacterized protein.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.966
Syvn1	sel1l	ENSCSEP00000021423	ENSCSEP00000030105	Uncharacterized protein.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.954
aup1	Syvn1	ENSCSEP00000026522	ENSCSEP00000021423	AUP1 lipid droplet regulating VLDL assembly factor.	Uncharacterized protein.	0.588
aup1	derl2	ENSCSEP00000026522	ENSCSEP00000014619	AUP1 lipid droplet regulating VLDL assembly factor.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.668
aup1	sel1l	ENSCSEP00000026522	ENSCSEP00000030105	AUP1 lipid droplet regulating VLDL assembly factor.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.847
derl1	Syvn1	ENSCSEP00000017906	ENSCSEP00000021423	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Uncharacterized protein.	0.969
derl1	derl2	ENSCSEP00000017906	ENSCSEP00000014619	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.998
derl1	sel1l	ENSCSEP00000017906	ENSCSEP00000030105	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.981
derl2	Syvn1	ENSCSEP00000014619	ENSCSEP00000021423	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Uncharacterized protein.	0.966
derl2	aup1	ENSCSEP00000014619	ENSCSEP00000026522	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	AUP1 lipid droplet regulating VLDL assembly factor.	0.668
derl2	derl1	ENSCSEP00000014619	ENSCSEP00000017906	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.998