45 items (Cynoglossus semilaevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rpa1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
	tp53inp1	Tumor protein p53 inducible nuclear protein 1. (298 aa)
	tp53inp2	Uncharacterized protein. (174 aa)
	klhl20	Kelch-like family member 20. (604 aa)
	hsf4	Heat shock transcription factor 4. (429 aa)
	n4bp1	Nedd4 binding protein 1. (1054 aa)
	ppargc1a	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (1262 aa)
	LOC103397830	Si:ch73-29c22.1. (268 aa)
	ankrd2	Ankyrin repeat domain 2 (stretch responsive muscle). (277 aa)
	rnf4	RING-type domain-containing protein. (246 aa)
	ankrd1	Ankyrin repeat domain 1a (cardiac muscle). (344 aa)
	chek2	Checkpoint kinase 2. (550 aa)
	rdm1	Zgc:103564. (287 aa)
	LOC103387374	RING-type domain-containing protein. (565 aa)
	ENSCSEP00000011692	Ubiquitin-like domain-containing protein. (102 aa)
	LOC103378618	Uncharacterized protein. (164 aa)
	LOC103395088	Transmembrane phosphatase with tensin homology. (510 aa)
	Mlip	Uncharacterized protein. (891 aa)
	Morc3	Uncharacterized protein. (168 aa)
	ENSCSEP00000017022	Uncharacterized protein. (117 aa)
	LOC103392195	Small ubiquitin-related modifier. (100 aa)
	sumo2	Ubiquitin-like domain-containing protein. (149 aa)
	LOC103378402	Small ubiquitin-related modifier. (94 aa)
	LOC103383557	Small ubiquitin-related modifier. (96 aa)
	pten	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (415 aa)
	LOC103395242	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (633 aa)
	rpain	RPA interacting protein. (253 aa)
	LOC103379412	Zgc:162297. (268 aa)
	trim8	Tripartite motif containing 8b. (592 aa)
	blm	BLM RecQ like helicase. (1300 aa)
	rnf111	Ring finger protein 111. (1040 aa)
	nagpa	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. (607 aa)
	ENSCSEP00000021195	RING-type domain-containing protein. (78 aa)
	LOC103391146	Germ cell nuclear acidic peptidase. (587 aa)
	Calcoco2	SKICH domain-containing protein. (175 aa)
	hsf2	Heat shock transcription factor 2. (542 aa)
	LOC103387686	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (457 aa)
	zbtb16	Zinc finger and BTB domain containing 16a. (662 aa)
	ENSCSEP00000025989	Ring finger protein (C3H2C3 type) 6. (593 aa)
	tdp2	Tyrosyl-DNA phosphodiesterase 2b. (360 aa)
	LOC103384950	KH and NYN domain containing. (741 aa)
	HSF1	Heat shock transcription factor 1. (466 aa)
	ENSCSEP00000028509	Uncharacterized protein. (1551 aa)
	ciita	Class II major histocompatibility complex transactivator. (918 aa)
	ENSCSEP00000029916	Death-domain associated protein. (681 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCSEP00000011692	ENSCSEP00000029916	ENSCSEP00000011692	ENSCSEP00000029916	Ubiquitin-like domain-containing protein.	Death-domain associated protein.	0.602
ENSCSEP00000011692	LOC103395242	ENSCSEP00000011692	ENSCSEP00000019947	Ubiquitin-like domain-containing protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.479
ENSCSEP00000011692	blm	ENSCSEP00000011692	ENSCSEP00000021128	Ubiquitin-like domain-containing protein.	BLM RecQ like helicase.	0.687
ENSCSEP00000011692	rnf111	ENSCSEP00000011692	ENSCSEP00000002441	Ubiquitin-like domain-containing protein.	Ring finger protein 111.	0.408
ENSCSEP00000011692	rnf4	ENSCSEP00000011692	ENSCSEP00000008386	Ubiquitin-like domain-containing protein.	RING-type domain-containing protein.	0.671
ENSCSEP00000011692	rpa1	ENSCSEP00000011692	ENSCSEP00000020488	Ubiquitin-like domain-containing protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.479
ENSCSEP00000011692	tdp2	ENSCSEP00000011692	ENSCSEP00000027219	Ubiquitin-like domain-containing protein.	Tyrosyl-DNA phosphodiesterase 2b.	0.588
ENSCSEP00000029916	ENSCSEP00000011692	ENSCSEP00000029916	ENSCSEP00000011692	Death-domain associated protein.	Ubiquitin-like domain-containing protein.	0.602
ENSCSEP00000029916	LOC103378402	ENSCSEP00000029916	ENSCSEP00000004643	Death-domain associated protein.	Small ubiquitin-related modifier.	0.602
ENSCSEP00000029916	LOC103383557	ENSCSEP00000029916	ENSCSEP00000004585	Death-domain associated protein.	Small ubiquitin-related modifier.	0.602
ENSCSEP00000029916	LOC103392195	ENSCSEP00000029916	ENSCSEP00000017973	Death-domain associated protein.	Small ubiquitin-related modifier.	0.602
ENSCSEP00000029916	rnf4	ENSCSEP00000029916	ENSCSEP00000008386	Death-domain associated protein.	RING-type domain-containing protein.	0.640
ENSCSEP00000029916	sumo2	ENSCSEP00000029916	ENSCSEP00000019858	Death-domain associated protein.	Ubiquitin-like domain-containing protein.	0.602
HSF1	LOC103395242	ENSCSEP00000028412	ENSCSEP00000019947	Heat shock transcription factor 1.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.467
HSF1	rpa1	ENSCSEP00000028412	ENSCSEP00000020488	Heat shock transcription factor 1.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.467
LOC103378402	ENSCSEP00000029916	ENSCSEP00000004643	ENSCSEP00000029916	Small ubiquitin-related modifier.	Death-domain associated protein.	0.602
LOC103378402	LOC103395242	ENSCSEP00000004643	ENSCSEP00000019947	Small ubiquitin-related modifier.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.479
LOC103378402	blm	ENSCSEP00000004643	ENSCSEP00000021128	Small ubiquitin-related modifier.	BLM RecQ like helicase.	0.687
LOC103378402	rnf111	ENSCSEP00000004643	ENSCSEP00000002441	Small ubiquitin-related modifier.	Ring finger protein 111.	0.408
LOC103378402	rnf4	ENSCSEP00000004643	ENSCSEP00000008386	Small ubiquitin-related modifier.	RING-type domain-containing protein.	0.671