(66 nodes) RmlC-like jelly roll fold network (Cynoglossus semilaevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSCSEP00000002948	Protein kinase, cAMP-dependent, regulatory, type II, alpha, B. (374 aa)
	Prkg2	cGMP-dependent protein kinase. (739 aa)
	LOC103398270	cGMP-dependent protein kinase. (683 aa)
	LOC103395957	Cyclic nucleotide-binding domain-containing protein. (1181 aa)
	LOC103395327	Cyclic nucleotide gated channel alpha 2b. (698 aa)
	prkar1b	Protein kinase, cAMP-dependent, regulatory, type I, beta. (383 aa)
	LOC103395904	Zgc:171558. (1028 aa)
	LOC103380454	Cyclic nucleotide-binding domain-containing protein. (1183 aa)
	bves	Blood vessel epicardial substance. (358 aa)
	kcnh5	Potassium voltage-gated channel, subfamily H (eag-related), member 5b. (1025 aa)
	LOC103384113	Patatin-like phospholipase domain containing 6. (1374 aa)
	jmjd7	Jumonji domain containing 7. (309 aa)
	LOC103393535	Protein kinase cAMP-dependent type I regulatory subunit alpha. (379 aa)
	rapgef6	Rap guanine nucleotide exchange factor (GEF) 6. (1565 aa)
	Kcnh8	Potassium voltage-gated channel, subfamily H (eag-related), member 8. (1029 aa)
	ENSCSEP00000018385	Cyclic nucleotide gated channel beta 3, tandem duplicate 1. (675 aa)
	ENSCSEP00000018378	Cyclic nucleotide gated channel beta 3, tandem duplicate 2. (645 aa)
	LOC103389942	Cyclin and CBS domain divalent metal cation transport mediator 4a. (634 aa)
	ado	2-aminoethanethiol (cysteamine) dioxygenase a. (258 aa)
	hgd	Homogentisate 1,2-dioxygenase. (442 aa)
	cnnm2	Cyclin and CBS domain divalent metal cation transport mediator 2b. (849 aa)
	ENSCSEP00000014729	Cyclic nucleotide gated channel subunit alpha 1a. (598 aa)
	ENSCSEP00000014360	Cyclic nucleotide-binding domain-containing protein. (531 aa)
	LOC103392003	Hyperpolarization activated cyclic nucleotide-gated potassium channel 5. (439 aa)
	ENSCSEP00000013893	Cysteine dioxygenase. (174 aa)
	LOC103379031	Hyperpolarization activated cyclic nucleotide-gated potassium channel 4. (1132 aa)
	ENSCSEP00000012148	Uncharacterized protein. (362 aa)
	ENSCSEP00000011876	Cyclic nucleotide-binding domain-containing protein. (823 aa)
	ENSCSEP00000011596	Cyclic nucleotide-binding domain-containing protein. (69 aa)
	ENSCSEP00000009383	Cyclic nucleotide-binding domain-containing protein. (619 aa)
	cnga4	Cyclic nucleotide gated channel subunit alpha 4. (610 aa)
	prkar2a	Protein kinase, cAMP-dependent, regulatory, type II, alpha A. (391 aa)
	ENSCSEP00000008570	Rap guanine nucleotide exchange factor (GEF) 4. (951 aa)
	cnga1	Cyclic nucleotide gated channel subunit alpha 1b. (645 aa)
	LOC103389440	Potassium channel, voltage gated eag related subfamily H, member 7. (1236 aa)
	hif1an	Hypoxia inducible factor 1 subunit alpha inhibitor. (354 aa)
	rapgef2	Rap guanine nucleotide exchange factor (GEF) 2. (1621 aa)
	ENSCSEP00000005321	Cyclic nucleotide-binding domain-containing protein. (1104 aa)
	prkar2b	Protein kinase cAMP-dependent type II regulatory subunit beta. (393 aa)
	CNGA3	Cyclic nucleotide gated channel subunit alpha 3. (719 aa)
	LOC103391564	Potassium voltage-gated channel, subfamily H (eag-related), member 3. (1243 aa)
	HCN2	Hyperpolarization activated cyclic nucleotide-gated potassium channel 2b. (1051 aa)
	LOC103387004	Uncharacterized protein. (982 aa)
	ENSCSEP00000003644	Uncharacterized protein; Belongs to the protein kinase superfamily. (453 aa)
	ENSCSEP00000003628	Cyclic nucleotide-binding domain-containing protein. (233 aa)
	mpi	Mannose-6-phosphate isomerase. (422 aa)
	LOC103386981	cGMP-dependent protein kinase. (743 aa)
	ENSCSEP00000002485	cGMP-dependent protein kinase. (700 aa)
	haao	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (287 aa)
	LOC103383363	Potassium voltage-gated channel, subfamily H (eag-related), member 1b. (975 aa)
	prkar1a	Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b. (257 aa)
	adi1	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (196 aa)
	LOC103397565	Patatin-like phospholipase domain containing 7b. (1320 aa)
	LOC103387682	cGMP-dependent protein kinase. (721 aa)
	LOC103385263	Rap guanine nucleotide exchange factor (GEF) 3. (792 aa)
	LOC103393183	Potassium voltage-gated channel, subfamily H (eag-related), member 4a. (1188 aa)
	LOC103377223	Uncharacterized protein. (1060 aa)
	cdo1	Cysteine dioxygenase. (201 aa)
	LOC103389207	Uncharacterized protein. (1332 aa)
	ENSCSEP00000030466	Cyclic nucleotide-binding domain-containing protein. (508 aa)
	LOC103390262	Hyperpolarization activated cyclic nucleotide-gated potassium channel 1. (940 aa)
	ENSCSEP00000031659	Cyclic nucleotide-binding domain-containing protein. (655 aa)
	ENSCSEP00000031859	Uncharacterized protein. (1005 aa)
	LOC103397876	Uncharacterized protein. (797 aa)
	ENSCSEP00000033127	Si:dkey-44k1.5. (733 aa)
	kcnh6	Potassium voltage-gated channel, subfamily H (eag-related), member 6a. (1212 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNGA3	ENSCSEP00000018378	ENSCSEP00000005218	ENSCSEP00000018378	Cyclic nucleotide gated channel subunit alpha 3.	Cyclic nucleotide gated channel beta 3, tandem duplicate 2.	0.715
CNGA3	ENSCSEP00000018385	ENSCSEP00000005218	ENSCSEP00000018385	Cyclic nucleotide gated channel subunit alpha 3.	Cyclic nucleotide gated channel beta 3, tandem duplicate 1.	0.718
CNGA3	ENSCSEP00000030466	ENSCSEP00000005218	ENSCSEP00000030466	Cyclic nucleotide gated channel subunit alpha 3.	Cyclic nucleotide-binding domain-containing protein.	0.752
CNGA3	ENSCSEP00000033127	ENSCSEP00000005218	ENSCSEP00000033127	Cyclic nucleotide gated channel subunit alpha 3.	Si:dkey-44k1.5.	0.754
ENSCSEP00000008570	LOC103385263	ENSCSEP00000008570	ENSCSEP00000026462	Rap guanine nucleotide exchange factor (GEF) 4.	Rap guanine nucleotide exchange factor (GEF) 3.	0.523
ENSCSEP00000009383	ENSCSEP00000018378	ENSCSEP00000009383	ENSCSEP00000018378	Cyclic nucleotide-binding domain-containing protein.	Cyclic nucleotide gated channel beta 3, tandem duplicate 2.	0.714
ENSCSEP00000009383	ENSCSEP00000018385	ENSCSEP00000009383	ENSCSEP00000018385	Cyclic nucleotide-binding domain-containing protein.	Cyclic nucleotide gated channel beta 3, tandem duplicate 1.	0.714
ENSCSEP00000009383	ENSCSEP00000030466	ENSCSEP00000009383	ENSCSEP00000030466	Cyclic nucleotide-binding domain-containing protein.	Cyclic nucleotide-binding domain-containing protein.	0.713
ENSCSEP00000009383	ENSCSEP00000033127	ENSCSEP00000009383	ENSCSEP00000033127	Cyclic nucleotide-binding domain-containing protein.	Si:dkey-44k1.5.	0.712
ENSCSEP00000014729	ENSCSEP00000018378	ENSCSEP00000014729	ENSCSEP00000018378	Cyclic nucleotide gated channel subunit alpha 1a.	Cyclic nucleotide gated channel beta 3, tandem duplicate 2.	0.717
ENSCSEP00000014729	ENSCSEP00000018385	ENSCSEP00000014729	ENSCSEP00000018385	Cyclic nucleotide gated channel subunit alpha 1a.	Cyclic nucleotide gated channel beta 3, tandem duplicate 1.	0.720
ENSCSEP00000014729	ENSCSEP00000030466	ENSCSEP00000014729	ENSCSEP00000030466	Cyclic nucleotide gated channel subunit alpha 1a.	Cyclic nucleotide-binding domain-containing protein.	0.716
ENSCSEP00000014729	ENSCSEP00000033127	ENSCSEP00000014729	ENSCSEP00000033127	Cyclic nucleotide gated channel subunit alpha 1a.	Si:dkey-44k1.5.	0.714
ENSCSEP00000014729	cnga1	ENSCSEP00000014729	ENSCSEP00000008244	Cyclic nucleotide gated channel subunit alpha 1a.	Cyclic nucleotide gated channel subunit alpha 1b.	0.903
ENSCSEP00000018378	CNGA3	ENSCSEP00000018378	ENSCSEP00000005218	Cyclic nucleotide gated channel beta 3, tandem duplicate 2.	Cyclic nucleotide gated channel subunit alpha 3.	0.715
ENSCSEP00000018378	ENSCSEP00000009383	ENSCSEP00000018378	ENSCSEP00000009383	Cyclic nucleotide gated channel beta 3, tandem duplicate 2.	Cyclic nucleotide-binding domain-containing protein.	0.714
ENSCSEP00000018378	ENSCSEP00000014729	ENSCSEP00000018378	ENSCSEP00000014729	Cyclic nucleotide gated channel beta 3, tandem duplicate 2.	Cyclic nucleotide gated channel subunit alpha 1a.	0.717
ENSCSEP00000018378	ENSCSEP00000031659	ENSCSEP00000018378	ENSCSEP00000031659	Cyclic nucleotide gated channel beta 3, tandem duplicate 2.	Cyclic nucleotide-binding domain-containing protein.	0.719
ENSCSEP00000018378	LOC103395327	ENSCSEP00000018378	ENSCSEP00000022162	Cyclic nucleotide gated channel beta 3, tandem duplicate 2.	Cyclic nucleotide gated channel alpha 2b.	0.716
ENSCSEP00000018378	cnga1	ENSCSEP00000018378	ENSCSEP00000008244	Cyclic nucleotide gated channel beta 3, tandem duplicate 2.	Cyclic nucleotide gated channel subunit alpha 1b.	0.718