STRINGSTRING
cftr cftr abcb6 abcb6 abcb8 abcb8 ENSCSEP00000018076 ENSCSEP00000018076 LOC103393517 LOC103393517 abca12 abca12 LOC103384135 LOC103384135 abcb9 abcb9 abcd4 abcd4 LOC103389776 LOC103389776 LOC103388956 LOC103388956 ENSCSEP00000022907 ENSCSEP00000022907 abcb7 abcb7 LOC103398783 LOC103398783 ENSCSEP00000025084 ENSCSEP00000025084 ENSCSEP00000026145 ENSCSEP00000026145 LOC103394946 LOC103394946 abcd1 abcd1 Abca7 Abca7 Abcf1 Abcf1 abcf2 abcf2 ENSCSEP00000031783 ENSCSEP00000031783 ENSCSEP00000032070 ENSCSEP00000032070 Abcb10 Abcb10 ABCA5 ABCA5 abcc3 abcc3 ENSCSEP00000002717 ENSCSEP00000002717 abcc5 abcc5 ENSCSEP00000005272 ENSCSEP00000005272 LOC103387097 LOC103387097 abcg8 abcg8 Abcg5 Abcg5 ABCG4 ABCG4 Abcb11 Abcb11 ABCC4 ABCC4 LOC103390790 LOC103390790 LOC103382616 LOC103382616 abcf3 abcf3 LOC103390832 LOC103390832 cutc cutc abca2 abca2 abcd3 abcd3 LOC103389889 LOC103389889
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cftrCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1456 aa)
abcb6ATP-binding cassette, sub-family B (MDR/TAP), member 6a. (856 aa)
abcb8ATP-binding cassette, sub-family B (MDR/TAP), member 8. (708 aa)
ENSCSEP00000018076ATP-binding cassette, sub-family C (CFTR/MRP), member 6a. (1499 aa)
LOC103393517ATP-binding cassette, sub-family C (CFTR/MRP), member 1. (1504 aa)
abca12ATP-binding cassette, sub-family A (ABC1), member 12. (4189 aa)
LOC103384135ATP-binding cassette, sub-family A (ABC1), member 1A. (2268 aa)
abcb9ATP-binding cassette, sub-family B (MDR/TAP), member 9. (800 aa)
abcd4ATP-binding cassette, sub-family D (ALD), member 4. (628 aa)
LOC103389776Uncharacterized protein. (1312 aa)
LOC103388956Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP). (735 aa)
ENSCSEP00000022907ATP-binding cassette, sub-family G (WHITE), member 4a. (615 aa)
abcb7ATP-binding cassette, sub-family B (MDR/TAP), member 7. (745 aa)
LOC103398783ATP-binding cassette, sub-family C (CFTR/MRP), member 8. (1486 aa)
ENSCSEP00000025084ATP-binding cassette, sub-family A (ABC1), member 3b. (1407 aa)
ENSCSEP00000026145ATP-binding cassette, sub-family A (ABC1), member 4b. (2168 aa)
LOC103394946ABC transporter domain-containing protein. (626 aa)
abcd1ATP-binding cassette, sub-family D (ALD), member 1. (773 aa)
Abca7Zgc:172302. (2330 aa)
Abcf1ATP-binding cassette, sub-family F (GCN20), member 1. (707 aa)
abcf2ATP-binding cassette, sub-family F (GCN20), member 2b. (612 aa)
ENSCSEP00000031783Uncharacterized protein. (1426 aa)
ENSCSEP00000032070ATP-binding cassette, sub-family C (CFTR/MRP), member 10. (1522 aa)
Abcb10ATP-binding cassette, sub-family B (MDR/TAP), member 10. (706 aa)
ABCA5ATP binding cassette subfamily A member 5. (1687 aa)
abcc3ATP-binding cassette, sub-family C (CFTR/MRP), member 3. (1512 aa)
ENSCSEP00000002717ATP-binding cassette, sub-family B (MDR/TAP), member 4. (1142 aa)
abcc5Si:ch211-221f10.2. (1410 aa)
ENSCSEP00000005272ATP-binding cassette, sub-family C (CFTR/MRP), member 9. (1531 aa)
LOC103387097ATP-binding cassette, sub-family H, member 1. (705 aa)
abcg8ATP-binding cassette, sub-family G (WHITE), member 8. (617 aa)
Abcg5ATP-binding cassette, sub-family G (WHITE), member 5. (642 aa)
ABCG4ATP binding cassette subfamily G member 4. (681 aa)
Abcb11ATP-binding cassette, sub-family B (MDR/TAP), member 11b. (1252 aa)
ABCC4ATP binding cassette subfamily C member 4. (1320 aa)
LOC103390790Uncharacterized protein. (2290 aa)
LOC103382616ATP-binding cassette, sub-family G (WHITE), member 1. (670 aa)
abcf3ATP-binding cassette, sub-family F (GCN20), member 3. (711 aa)
LOC103390832Uncharacterized protein. (2004 aa)
cutcUncharacterized protein. (1614 aa)
abca2ATP-binding cassette, sub-family A (ABC1), member 2. (2424 aa)
abcd3ATP-binding cassette, sub-family D (ALD), member 3a. (660 aa)
LOC103389889Uncharacterized protein. (1143 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.