STRINGSTRING
pole3 pole3 rfc1 rfc1 RCBTB1 RCBTB1 rad18 rad18 Cul4b Cul4b rps27a rps27a meiob meiob LOC103378632 LOC103378632 rfc4 rfc4 pole2 pole2 uba52 uba52 POLE POLE usp1 usp1 rpa2 rpa2 rfc2 rfc2 pcna pcna pole4 pole4 LOC103397632 LOC103397632 dtl dtl rfc5 rfc5 Pold2 Pold2 pold4 pold4 UBB UBB ENSCSEP00000023759 ENSCSEP00000023759 pold1 pold1 rpa1 rpa1 ENSCSEP00000020203 ENSCSEP00000020203 ENSCSEP00000020096 ENSCSEP00000020096 LOC103395242 LOC103395242 ddb1 ddb1 rfc3 rfc3 pold2 pold2 wdr48 wdr48 ENSCSEP00000012655 ENSCSEP00000012655 ENSCSEP00000011696 ENSCSEP00000011696 rcbtb2 rcbtb2 pold3 pold3 rbx1 rbx1 ENSCSEP00000009964 ENSCSEP00000009964 kxd1 kxd1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (149 aa)
rfc1Replication factor C subunit 1. (1083 aa)
RCBTB1Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (637 aa)
rad18RAD18 E3 ubiquitin protein ligase. (507 aa)
Cul4bCullin 4B; Belongs to the cullin family. (825 aa)
rps27aRibosomal protein S27a. (156 aa)
meiobMethionine sulfoxide reductase B1b. (436 aa)
LOC103378632Cullin 4A; Belongs to the cullin family. (759 aa)
rfc4Replication factor C (activator 1) 4. (358 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (151 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1996 aa)
usp1Ubiquitin carboxyl-terminal hydrolase. (798 aa)
rpa2Replication protein A2. (274 aa)
rfc2Replication factor C (activator 1) 2. (355 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (130 aa)
LOC103397632SCY domain-containing protein. (159 aa)
dtlDenticleless E3 ubiquitin protein ligase homolog (Drosophila). (654 aa)
rfc5Replication factor C (activator 1) 5. (338 aa)
Pold2Uncharacterized protein. (78 aa)
pold4Si:dkey-28b4.7. (109 aa)
UBBUbiquitin B. (744 aa)
ENSCSEP00000023759Ubiquitin-like domain-containing protein. (92 aa)
pold1DNA polymerase. (1077 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
ENSCSEP00000020203DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (315 aa)
ENSCSEP00000020096Uncharacterized protein. (707 aa)
LOC103395242Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (633 aa)
ddb1Damage-specific DNA binding protein 1. (1137 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (519 aa)
wdr48WD repeat domain 48b. (643 aa)
ENSCSEP00000012655DNA_pol_D_N domain-containing protein. (396 aa)
ENSCSEP00000011696Uncharacterized protein. (103 aa)
rcbtb2Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (554 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (419 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
ENSCSEP00000009964Uncharacterized protein. (85 aa)
kxd1KxDL motif containing 1. (180 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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