node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSCSEP00000016629 | Mtr | ENSCSEP00000016629 | ENSCSEP00000004127 | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.947 |
LOC103387328 | MAT1A | ENSCSEP00000010528 | ENSCSEP00000014708 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.900 |
LOC103387328 | Mtr | ENSCSEP00000010528 | ENSCSEP00000004127 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.959 |
LOC103387328 | ahcy | ENSCSEP00000010528 | ENSCSEP00000031525 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | 0.605 |
LOC103387328 | mat2a | ENSCSEP00000010528 | ENSCSEP00000002641 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.901 |
LOC103387328 | mat2b | ENSCSEP00000010528 | ENSCSEP00000010502 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | 0.991 |
MAT1A | LOC103387328 | ENSCSEP00000014708 | ENSCSEP00000010528 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.900 |
MAT1A | Mtr | ENSCSEP00000014708 | ENSCSEP00000004127 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.959 |
MAT1A | ahcy | ENSCSEP00000014708 | ENSCSEP00000031525 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | 0.605 |
MAT1A | mat2a | ENSCSEP00000014708 | ENSCSEP00000002641 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.901 |
MAT1A | mat2b | ENSCSEP00000014708 | ENSCSEP00000010502 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | 0.991 |
Mtr | ENSCSEP00000016629 | ENSCSEP00000004127 | ENSCSEP00000016629 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase. | 0.947 |
Mtr | LOC103387328 | ENSCSEP00000004127 | ENSCSEP00000010528 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.959 |
Mtr | MAT1A | ENSCSEP00000004127 | ENSCSEP00000014708 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.959 |
Mtr | ahcy | ENSCSEP00000004127 | ENSCSEP00000031525 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | 0.970 |
Mtr | mat2a | ENSCSEP00000004127 | ENSCSEP00000002641 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.959 |
Mtr | mat2b | ENSCSEP00000004127 | ENSCSEP00000010502 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | 0.933 |
ahcy | LOC103387328 | ENSCSEP00000031525 | ENSCSEP00000010528 | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.605 |
ahcy | MAT1A | ENSCSEP00000031525 | ENSCSEP00000014708 | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.605 |
ahcy | Mtr | ENSCSEP00000031525 | ENSCSEP00000004127 | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.970 |