STRINGSTRING
LOC103384737 LOC103384737 LOC103384692 LOC103384692 fkbp1b fkbp1b atp1b4 atp1b4 rnf111 rnf111 rps27a rps27a LOC103379842 LOC103379842 LOC103377523 LOC103377523 itgb6 itgb6 ltbp2 ltbp2 LOC103376789 LOC103376789 LTBP3 LTBP3 LOC103396454 LOC103396454 ENSCSEP00000022604 ENSCSEP00000022604 ENSCSEP00000022726 ENSCSEP00000022726 LOC103395304 LOC103395304 TGFBR2 TGFBR2 ENSCSEP00000023418 ENSCSEP00000023418 ENSCSEP00000023438 ENSCSEP00000023438 LOC103393685 LOC103393685 cblc cblc ENSCSEP00000023759 ENSCSEP00000023759 LOC103394304 LOC103394304 ENSCSEP00000024394 ENSCSEP00000024394 CDK19 CDK19 ncor1 ncor1 UBB UBB strap strap uba52 uba52 cbl cbl ENSCSEP00000025842 ENSCSEP00000025842 LOC103395395 LOC103395395 cdk8 cdk8 ENSCSEP00000025934 ENSCSEP00000025934 SMAD4 SMAD4 Mkx Mkx LOC103385296 LOC103385296 LOC103393219 LOC103393219 ccnk ccnk snw1 snw1 CCNT2 CCNT2 LOC103397828 LOC103397828 ccnc ccnc LOC103392486 LOC103392486 nedd4l nedd4l smad7 smad7 smad2 smad2 rbl1 rbl1 LOC103386783 LOC103386783 TGFB3 TGFB3 LOC103385393 LOC103385393 parp1 parp1 LOC103391513 LOC103391513 e2f4 e2f4 zfyve9 zfyve9 ENSCSEP00000033647 ENSCSEP00000033647 ENSCSEP00000033853 ENSCSEP00000033853 LOC103379771 LOC103379771 LOC103389871 LOC103389871 tgfb2 tgfb2 LOC103381684 LOC103381684 LOC103394100 LOC103394100 LOC103394101 LOC103394101 PARD3 PARD3 SMAD3 SMAD3 LOC103378224 LOC103378224 ldlrad4 ldlrad4 LOC103377095 LOC103377095 furin furin LOC103377099 LOC103377099 ENSCSEP00000021801 ENSCSEP00000021801 LOC103396440 LOC103396440 LOC103393525 LOC103393525 LOC103384202 LOC103384202 LOC103396445 LOC103396445 LOC103393707 LOC103393707 ENSCSEP00000022461 ENSCSEP00000022461 LOC103388716 LOC103388716 LOC103383976 LOC103383976 LOC103397451 LOC103397451 cdk9 cdk9 sarnp sarnp LOC103389682 LOC103389682 irx3 irx3 itgb8 itgb8 ENSCSEP00000012341 ENSCSEP00000012341 LOC103376883 LOC103376883 MAPK1 MAPK1 irx6 irx6 ENSCSEP00000011691 ENSCSEP00000011691 LOC103381463 LOC103381463 ENSCSEP00000011399 ENSCSEP00000011399 LOC103380246 LOC103380246 LOC103397887 LOC103397887 smurf1 smurf1 kxd1 kxd1 LOC103378886 LOC103378886 LOC103390834 LOC103390834 FBN1 FBN1 LOC103377845 LOC103377845 LOC103391805 LOC103391805 ENSCSEP00000007724 ENSCSEP00000007724 meis2 meis2 LOC103386120 LOC103386120 LOC103388364 LOC103388364 tfdp1 tfdp1 LOC103388329 LOC103388329 irx2 irx2 ENSCSEP00000006129 ENSCSEP00000006129 LOC103387108 LOC103387108 itgb5 itgb5 ccnq ccnq prkcz prkcz
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103384737V-ski avian sarcoma viral oncogene homolog a. (736 aa)
LOC103384692Peptidylprolyl isomerase. (108 aa)
fkbp1bPeptidylprolyl isomerase. (108 aa)
atp1b4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (393 aa)
rnf111Ring finger protein 111. (1040 aa)
rps27aRibosomal protein S27a. (156 aa)
LOC103379842Par-6 family cell polarity regulator alpha. (440 aa)
LOC103377523TGFB-induced factor homeobox 1. (252 aa)
itgb6Integrin beta; Belongs to the integrin beta chain family. (777 aa)
ltbp2Uncharacterized protein. (2089 aa)
LOC103376789Transforming growth factor beta; Belongs to the TGF-beta family. (403 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1221 aa)
LOC103396454SKI-like proto-oncogene a. (766 aa)
ENSCSEP00000022604Mothers against decapentaplegic homolog. (472 aa)
ENSCSEP00000022726Multiple endocrine neoplasia I. (411 aa)
LOC103395304F11 receptor, tandem duplicate 1. (297 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (578 aa)
ENSCSEP00000023418Uncharacterized protein. (258 aa)
ENSCSEP00000023438Uncharacterized protein. (259 aa)
LOC103393685JunB proto-oncogene, AP-1 transcription factor subunit b. (334 aa)
cblcCbl proto-oncogene C, E3 ubiquitin protein ligase. (550 aa)
ENSCSEP00000023759Ubiquitin-like domain-containing protein. (92 aa)
LOC103394304Mothers against decapentaplegic homolog. (573 aa)
ENSCSEP00000024394Uncharacterized protein. (2211 aa)
CDK19Cyclin dependent kinase 19; Belongs to the protein kinase superfamily. (487 aa)
ncor1Nuclear receptor corepressor 1. (2354 aa)
UBBUbiquitin B. (744 aa)
strapSerine/threonine kinase receptor associated protein. (329 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (151 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (952 aa)
ENSCSEP00000025842Latent transforming growth factor beta binding protein 1. (1174 aa)
LOC103395395Uncharacterized protein. (869 aa)
cdk8Cyclin-dependent kinase 8; Belongs to the protein kinase superfamily. (464 aa)
ENSCSEP00000025934Integrin beta; Belongs to the integrin beta chain family. (750 aa)
SMAD4Mothers against decapentaplegic homolog. (503 aa)
MkxMohawk homeobox b. (263 aa)
LOC103385296Iroquois homeobox 7. (331 aa)
LOC103393219Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (405 aa)
ccnkCyclin K; Belongs to the cyclin family. (551 aa)
snw1SNW domain containing 1. (519 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (723 aa)
LOC103397828Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa)
ccncCyclin C; Belongs to the cyclin family. (283 aa)
LOC103392486Par-3 family cell polarity regulator beta b. (1190 aa)
nedd4lNEDD4 like E3 ubiquitin protein ligase. (1007 aa)
smad7Mothers against decapentaplegic homolog. (376 aa)
smad2Mothers against decapentaplegic homolog. (474 aa)
rbl1Retinoblastoma-like 1 (p107). (1066 aa)
LOC103386783Uncharacterized protein. (275 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
LOC103385393Peptidylprolyl isomerase. (109 aa)
parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa)
LOC103391513TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
e2f4E2F transcription factor 4. (385 aa)
zfyve9Zinc finger, FYVE domain containing 9a. (1188 aa)
ENSCSEP00000033647Par-3 family cell polarity regulator alpha, b. (1325 aa)
ENSCSEP00000033853V-ski avian sarcoma viral oncogene homolog b. (658 aa)
LOC103379771Homeobox domain-containing protein. (385 aa)
LOC103389871Par-3 family cell polarity regulator beta a. (1243 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
LOC103381684STIP1 homology and U-Box containing protein 1. (159 aa)
LOC103394100Iroquois homeobox 1b. (465 aa)
LOC103394101Iroquois homeobox 4b. (461 aa)
PARD3Par-3 family cell polarity regulator. (1336 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
LOC103378224Myeloid ecotropic viral integration site 3. (405 aa)
ldlrad4Low density lipoprotein receptor class A domain containing 4b. (320 aa)
LOC103377095Mohawk homeobox a. (400 aa)
furinFurin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family. (834 aa)
LOC103377099BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
ENSCSEP00000021801BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a. (145 aa)
LOC103396440Peptidylprolyl isomerase. (109 aa)
LOC103393525Rho/rac guanine nucleotide exchange factor (GEF) 18b. (1428 aa)
LOC103384202JunB proto-oncogene, AP-1 transcription factor subunit a. (333 aa)
LOC103396445E2F transcription factor 5. (360 aa)
LOC103393707SMAD specific E3 ubiquitin protein ligase 2. (794 aa)
ENSCSEP00000022461C2 domain-containing protein. (54 aa)
LOC103388716TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (586 aa)
LOC103383976E3 ubiquitin-protein ligase. (777 aa)
LOC103397451Mothers against decapentaplegic homolog. (437 aa)
cdk9Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily. (393 aa)
sarnpCyclin T1; Belongs to the cyclin family. (674 aa)
LOC103389682Cyclin T2b; Belongs to the cyclin family. (542 aa)
irx3Iroquois homeobox 3a. (431 aa)
itgb8Integrin beta; Belongs to the integrin beta chain family. (801 aa)
ENSCSEP00000012341Par3_HAL_N_term domain-containing protein. (50 aa)
LOC103376883Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
MAPK1Mitogen-activated protein kinase 1. (172 aa)
irx6Iroquois homeobox 6a. (501 aa)
ENSCSEP00000011691Iroquois homeobox 5a. (448 aa)
LOC103381463Integrin beta; Belongs to the integrin beta chain family. (854 aa)
ENSCSEP00000011399Uncharacterized protein. (102 aa)
LOC103380246Mothers against decapentaplegic homolog. (425 aa)
LOC103397887Mothers against decapentaplegic homolog. (510 aa)
smurf1E3 ubiquitin-protein ligase. (729 aa)
kxd1KxDL motif containing 1. (180 aa)
LOC103378886Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (949 aa)
LOC103390834Transforming growth factor beta; Belongs to the TGF-beta family. (421 aa)
FBN1Fibrillin 1. (2888 aa)
LOC103377845Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
LOC103391805Ubiquitin specific peptidase 9; Belongs to the peptidase C19 family. (2613 aa)
ENSCSEP00000007724Tripartite motif containing 33. (1109 aa)
meis2Meis homeobox 2a. (510 aa)
LOC103386120Homeobox domain-containing protein. (584 aa)
LOC103388364Ubiquitin-like domain-containing protein. (81 aa)
tfdp1Transcription factor. (412 aa)
LOC103388329Iroquois homeobox 4a. (476 aa)
irx2Iroquois homeobox 2a. (528 aa)
ENSCSEP00000006129Iroquois homeobox 1a. (397 aa)
LOC103387108Meis homeobox 1 b. (349 aa)
itgb5Integrin beta; Belongs to the integrin beta chain family. (780 aa)
ccnqCyclin Q; Belongs to the cyclin family. (258 aa)
prkczProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (601 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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