STRINGSTRING
grb2 grb2 LOC103390060 LOC103390060 LOC103397209 LOC103397209 LOC103392975 LOC103392975 gtf2f1 gtf2f1 LOC103392281 LOC103392281 ENSCSEP00000020731 ENSCSEP00000020731 Shc4 Shc4 fgf7 fgf7 LOC103384120 LOC103384120 LOC103387590 LOC103387590 kl kl NCBP1 NCBP1 LOC103395214 LOC103395214 polr2g polr2g LOC103379359 LOC103379359 tial1 tial1 klb klb tia1 tia1 ppp2cb ppp2cb FGF10 FGF10 ANOS1 ANOS1 Spry2 Spry2 GALNT3 GALNT3 hras hras ENSCSEP00000012109 ENSCSEP00000012109 ENSCSEP00000011964 ENSCSEP00000011964 MAPK1 MAPK1 LOC103385130 LOC103385130 ENSCSEP00000011448 ENSCSEP00000011448 fndc3a fndc3a POLR2E POLR2E fgf19 fgf19 fgf4 fgf4 lctl lctl fgf3 fgf3 PTBP2 PTBP2 flrt3 flrt3 fgf23 fgf23 FGF6 FGF6 polr2f polr2f LOC103390897 LOC103390897 polr2d polr2d LOC103390821 LOC103390821 kras kras polr2b polr2b ptbp1 ptbp1 spred1 spred1 LOC103390704 LOC103390704 fgf2 fgf2 LOC103390679 LOC103390679 fgfbp3 fgfbp3 Fgfbp2 Fgfbp2 spred2 spred2 LOC103390636 LOC103390636 fndc3b fndc3b LOC103399916 LOC103399916 polr2a polr2a CSDE1 CSDE1 polr2i polr2i shc1 shc1 polr2l polr2l ENSCSEP00000002772 ENSCSEP00000002772 polr2c polr2c esrp1 esrp1 rps27a rps27a LOC103385760 LOC103385760 FGFRL1 FGFRL1 LOC103384588 LOC103384588 ENSCSEP00000033458 ENSCSEP00000033458 FGF6-2 FGF6-2 gab1 gab1 PLCG1 PLCG1 ENSCSEP00000032733 ENSCSEP00000032733 PTBP3 PTBP3 polr2j polr2j LOC103397742 LOC103397742 mknk1 mknk1 LOC103386740 LOC103386740 PIK3CA PIK3CA ncbp2 ncbp2 ENSCSEP00000029949 ENSCSEP00000029949 LOC103397828 LOC103397828 flrt2 flrt2 LOC103378498 LOC103378498 lct lct LOC103396554 LOC103396554 LOC103391367 LOC103391367 LOC103389109 LOC103389109 LOC103393219 LOC103393219 LOC103395232 LOC103395232 polr2k polr2k LOC103391274 LOC103391274 LOC103396148 LOC103396148 fgf8 fgf8 mknk2 mknk2 LOC103395395 LOC103395395 gtf2f2 gtf2f2 LOC103394934 LOC103394934 ENSCSEP00000025543 ENSCSEP00000025543 cbl cbl uba52 uba52 UBB UBB fgf5 fgf5 LOC103394884 LOC103394884 LOC103391208 LOC103391208 polr2h polr2h ppp2ca ppp2ca LOC103391194 LOC103391194 fgfr3 fgfr3 ENSCSEP00000023759 ENSCSEP00000023759 cblc cblc hnrnpm hnrnpm fgf16 fgf16 LOC103385228 LOC103385228
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
grb2Growth factor receptor-bound protein 2b. (220 aa)
LOC103390060Cytotoxic granule-associated RNA binding protein 1, like. (385 aa)
LOC103397209Uncharacterized protein. (387 aa)
LOC103392975Zgc:55558. (187 aa)
gtf2f1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (533 aa)
LOC103392281General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (277 aa)
ENSCSEP00000020731Anosmin 1a. (409 aa)
Shc4Uncharacterized protein. (342 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (202 aa)
LOC103384120Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
LOC103387590Uncharacterized protein. (271 aa)
klKlotho. (979 aa)
NCBP1Nuclear cap binding protein subunit 1. (822 aa)
LOC103395214Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (149 aa)
polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (190 aa)
LOC103379359Epithelial splicing regulatory protein 2. (738 aa)
tial1TIA1 cytotoxic granule-associated RNA binding protein-like 1. (384 aa)
klbKlotho beta. (1057 aa)
tia1Uncharacterized protein. (405 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
ANOS1Anosmin 1. (675 aa)
Spry2Sprouty RTK signaling antagonist 2. (418 aa)
GALNT3Polypeptide N-acetylgalactosaminyltransferase. (625 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
ENSCSEP00000012109Metallophos domain-containing protein. (79 aa)
ENSCSEP00000011964Uncharacterized protein. (821 aa)
MAPK1Mitogen-activated protein kinase 1. (172 aa)
LOC103385130Heterogeneous nuclear ribonucleoprotein A1a. (350 aa)
ENSCSEP00000011448PI3K-ABD domain-containing protein; Belongs to the PI3/PI4-kinase family. (123 aa)
fndc3aFibronectin type III domain containing 3A. (1276 aa)
POLR2ERNA polymerase II subunit E. (229 aa)
fgf19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
lctlLactase-like b; Belongs to the glycosyl hydrolase 1 family. (570 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (248 aa)
PTBP2Polypyrimidine tract binding protein 2a. (518 aa)
flrt3Fibronectin leucine rich transmembrane 3. (649 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (265 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (185 aa)
polr2fPolymerase (RNA) II (DNA directed) polypeptide F. (127 aa)
LOC103390897Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (211 aa)
polr2dPolymerase (RNA) II (DNA directed) polypeptide D. (144 aa)
LOC103390821Fibronectin leucine rich transmembrane protein 1b. (635 aa)
krasV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
polr2bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
ptbp1Polypyrimidine tract binding protein 1a. (541 aa)
spred1Sprouty related EVH1 domain containing 1. (436 aa)
LOC103390704Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
LOC103390679Fibroblast growth factor binding protein 1b. (201 aa)
fgfbp3Uncharacterized protein. (199 aa)
Fgfbp2Fibroblast growth factor binding protein 2b. (270 aa)
spred2Sprouty related EVH1 domain containing 2b. (463 aa)
LOC103390636Fibroblast growth factor receptor like 1a. (499 aa)
fndc3bFibronectin type III domain containing 3Ba. (1205 aa)
LOC103399916Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1965 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (917 aa)
polr2iPolymerase (RNA) II (DNA directed) polypeptide I. (287 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (731 aa)
polr2lPolymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
ENSCSEP00000002772Fibroblast growth factor receptor. (689 aa)
polr2cPolymerase (RNA) II (DNA directed) polypeptide C. (275 aa)
esrp1Epithelial splicing regulatory protein 1. (688 aa)
rps27aRibosomal protein S27a. (156 aa)
LOC103385760Fibroblast growth factor receptor substrate 3. (616 aa)
FGFRL1Fibroblast growth factor receptor like 1. (496 aa)
LOC103384588Polypeptide N-acetylgalactosaminyltransferase. (620 aa)
ENSCSEP00000033458Fibroblast growth factor receptor substrate 2b. (492 aa)
FGF6-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (278 aa)
gab1GRB2-associated binding protein 1. (835 aa)
PLCG1Phosphoinositide phospholipase C. (474 aa)
ENSCSEP00000032733Uncharacterized protein. (132 aa)
PTBP3Polypyrimidine tract binding protein 3. (492 aa)
polr2jPolymerase (RNA) II (DNA directed) polypeptide J. (117 aa)
LOC103397742Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
mknk1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (464 aa)
LOC103386740Tyrosine-protein kinase. (558 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ncbp2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (189 aa)
ENSCSEP00000029949Uncharacterized protein. (244 aa)
LOC103397828Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa)
flrt2Fibronectin leucine rich transmembrane protein 2. (664 aa)
LOC103378498Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
lctLactase. (1881 aa)
LOC103396554Uncharacterized protein. (523 aa)
LOC103391367Fibroblast growth factor receptor 2. (661 aa)
LOC103389109Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (359 aa)
LOC103393219Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (405 aa)
LOC103395232Anosmin 1b. (674 aa)
polr2kPolymerase (RNA) II (DNA directed) polypeptide K. (58 aa)
LOC103391274Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (393 aa)
LOC103396148Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
mknk2MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (475 aa)
LOC103395395Uncharacterized protein. (869 aa)
gtf2f2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (270 aa)
LOC103394934Fibroblast growth factor receptor 4. (945 aa)
ENSCSEP00000025543Fibroblast growth factor receptor. (675 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (952 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (151 aa)
UBBUbiquitin B. (744 aa)
fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (235 aa)
LOC103394884Fibronectin type-III domain-containing protein. (682 aa)
LOC103391208Serine/threonine-protein phosphatase. (309 aa)
polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (155 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
LOC103391194Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (156 aa)
fgfr3Fibroblast growth factor receptor. (812 aa)
ENSCSEP00000023759Ubiquitin-like domain-containing protein. (92 aa)
cblcCbl proto-oncogene C, E3 ubiquitin protein ligase. (550 aa)
hnrnpmHeterogeneous nuclear ribonucleoprotein M. (690 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
LOC103385228Tyrosine-protein kinase. (551 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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