STRINGSTRING
ENSCSEP00000021801 ENSCSEP00000021801 LOC103396440 LOC103396440 ENSCSEP00000022604 ENSCSEP00000022604 TGFBR2 TGFBR2 ENSCSEP00000023418 ENSCSEP00000023418 ENSCSEP00000023438 ENSCSEP00000023438 LOC103378886 LOC103378886 LOC103376883 LOC103376883 SMAD3 SMAD3 ldlrad4 ldlrad4 furin furin LOC103377099 LOC103377099 LOC103381463 LOC103381463 LOC103380246 LOC103380246 LOC103397887 LOC103397887 kxd1 kxd1 ENSCSEP00000025842 ENSCSEP00000025842 LOC103390834 LOC103390834 FBN1 FBN1 LOC103377845 LOC103377845 LOC103388364 LOC103388364 itgb5 itgb5 LOC103384692 LOC103384692 fkbp1b fkbp1b rps27a rps27a itgb6 itgb6 ltbp2 ltbp2 LOC103376789 LOC103376789 LOC103385393 LOC103385393 LOC103391513 LOC103391513 zfyve9 zfyve9 cblc cblc ENSCSEP00000023759 ENSCSEP00000023759 LOC103394304 LOC103394304 smad7 smad7 itgb8 itgb8 LOC103397451 LOC103397451 LOC103388716 LOC103388716 tgfb2 tgfb2 LOC103381684 LOC103381684 SMAD4 SMAD4 smad2 smad2 LTBP3 LTBP3 LOC103386783 LOC103386783 TGFB3 TGFB3 LOC103395395 LOC103395395 ENSCSEP00000025934 ENSCSEP00000025934 ENSCSEP00000024394 ENSCSEP00000024394 UBB UBB strap strap uba52 uba52 cbl cbl
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSCSEP00000021801BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a. (145 aa)
LOC103396440Peptidylprolyl isomerase. (109 aa)
ENSCSEP00000022604Mothers against decapentaplegic homolog. (472 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (578 aa)
ENSCSEP00000023418Uncharacterized protein. (258 aa)
ENSCSEP00000023438Uncharacterized protein. (259 aa)
LOC103378886Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (949 aa)
LOC103376883Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
ldlrad4Low density lipoprotein receptor class A domain containing 4b. (320 aa)
furinFurin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family. (834 aa)
LOC103377099BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
LOC103381463Integrin beta; Belongs to the integrin beta chain family. (854 aa)
LOC103380246Mothers against decapentaplegic homolog. (425 aa)
LOC103397887Mothers against decapentaplegic homolog. (510 aa)
kxd1KxDL motif containing 1. (180 aa)
ENSCSEP00000025842Latent transforming growth factor beta binding protein 1. (1174 aa)
LOC103390834Transforming growth factor beta; Belongs to the TGF-beta family. (421 aa)
FBN1Fibrillin 1. (2888 aa)
LOC103377845Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
LOC103388364Ubiquitin-like domain-containing protein. (81 aa)
itgb5Integrin beta; Belongs to the integrin beta chain family. (780 aa)
LOC103384692Peptidylprolyl isomerase. (108 aa)
fkbp1bPeptidylprolyl isomerase. (108 aa)
rps27aRibosomal protein S27a. (156 aa)
itgb6Integrin beta; Belongs to the integrin beta chain family. (777 aa)
ltbp2Uncharacterized protein. (2089 aa)
LOC103376789Transforming growth factor beta; Belongs to the TGF-beta family. (403 aa)
LOC103385393Peptidylprolyl isomerase. (109 aa)
LOC103391513TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
zfyve9Zinc finger, FYVE domain containing 9a. (1188 aa)
cblcCbl proto-oncogene C, E3 ubiquitin protein ligase. (550 aa)
ENSCSEP00000023759Ubiquitin-like domain-containing protein. (92 aa)
LOC103394304Mothers against decapentaplegic homolog. (573 aa)
smad7Mothers against decapentaplegic homolog. (376 aa)
itgb8Integrin beta; Belongs to the integrin beta chain family. (801 aa)
LOC103397451Mothers against decapentaplegic homolog. (437 aa)
LOC103388716TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (586 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
LOC103381684STIP1 homology and U-Box containing protein 1. (159 aa)
SMAD4Mothers against decapentaplegic homolog. (503 aa)
smad2Mothers against decapentaplegic homolog. (474 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1221 aa)
LOC103386783Uncharacterized protein. (275 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
LOC103395395Uncharacterized protein. (869 aa)
ENSCSEP00000025934Integrin beta; Belongs to the integrin beta chain family. (750 aa)
ENSCSEP00000024394Uncharacterized protein. (2211 aa)
UBBUbiquitin B. (744 aa)
strapSerine/threonine kinase receptor associated protein. (329 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (151 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (952 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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