28 items (Cynoglossus semilaevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	syk	Spleen tyrosine kinase. (651 aa)
	ENSCSEP00000020564	Protein kinase domain-containing protein. (75 aa)
	Shc4	Uncharacterized protein. (342 aa)
	ENSCSEP00000018048	Calponin-homology (CH) domain-containing protein. (83 aa)
	spns1	Spinster homolog 1 (Drosophila). (511 aa)
	ENSCSEP00000011750	Uncharacterized protein. (84 aa)
	ENSCSEP00000011448	PI3K-ABD domain-containing protein; Belongs to the PI3/PI4-kinase family. (123 aa)
	ENSCSEP00000010489	Lymphocyte cytosolic protein 2a. (353 aa)
	vav2	Vav 2 guanine nucleotide exchange factor. (828 aa)
	LOC103378673	Tyrosine-protein kinase. (537 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (917 aa)
	LOC103399890	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1245 aa)
	VAV1	Vav guanine nucleotide exchange factor 1. (840 aa)
	shc1	SHC (Src homology 2 domain containing) transforming protein 1. (731 aa)
	plcg2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1236 aa)
	lck	Tyrosine-protein kinase. (487 aa)
	ENSCSEP00000025299	Calponin-homology (CH) domain-containing protein. (69 aa)
	ENSCSEP00000025343	Vav 3 guanine nucleotide exchange factor b. (778 aa)
	LOC103396148	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
	FYN	Tyrosine-protein kinase. (482 aa)
	LOC103396202	Polymeric immunoglobulin receptor. (339 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC103392516	GRB2 related adaptor protein 2a. (290 aa)
	ENSCSEP00000032733	Uncharacterized protein. (132 aa)
	PLCG1	Phosphoinositide phospholipase C. (474 aa)
	grb2	Growth factor receptor-bound protein 2b. (220 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (737 aa)
	pik3cb	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1079 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	ENSCSEP00000011448	ENSCSEP00000004032	ENSCSEP00000011448	Cold shock domain containing E1, RNA-binding.	PI3K-ABD domain-containing protein; Belongs to the PI3/PI4-kinase family.	0.525
CSDE1	FYN	ENSCSEP00000004032	ENSCSEP00000026991	Cold shock domain containing E1, RNA-binding.	Tyrosine-protein kinase.	0.410
CSDE1	LOC103378673	ENSCSEP00000004032	ENSCSEP00000004735	Cold shock domain containing E1, RNA-binding.	Tyrosine-protein kinase.	0.410
CSDE1	LOC103396148	ENSCSEP00000004032	ENSCSEP00000026590	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.525
CSDE1	PIK3CA	ENSCSEP00000004032	ENSCSEP00000030420	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.525
CSDE1	Shc4	ENSCSEP00000004032	ENSCSEP00000020040	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein.	0.432
CSDE1	grb2	ENSCSEP00000004032	ENSCSEP00000022549	Cold shock domain containing E1, RNA-binding.	Growth factor receptor-bound protein 2b.	0.680
CSDE1	pik3cb	ENSCSEP00000004032	ENSCSEP00000020778	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.525
CSDE1	shc1	ENSCSEP00000004032	ENSCSEP00000003236	Cold shock domain containing E1, RNA-binding.	SHC (Src homology 2 domain containing) transforming protein 1.	0.432
ENSCSEP00000010489	ENSCSEP00000011750	ENSCSEP00000010489	ENSCSEP00000011750	Lymphocyte cytosolic protein 2a.	Uncharacterized protein.	0.763
ENSCSEP00000010489	ENSCSEP00000018048	ENSCSEP00000010489	ENSCSEP00000018048	Lymphocyte cytosolic protein 2a.	Calponin-homology (CH) domain-containing protein.	0.754
ENSCSEP00000010489	ENSCSEP00000020564	ENSCSEP00000010489	ENSCSEP00000020564	Lymphocyte cytosolic protein 2a.	Protein kinase domain-containing protein.	0.510
ENSCSEP00000010489	ENSCSEP00000025299	ENSCSEP00000010489	ENSCSEP00000025299	Lymphocyte cytosolic protein 2a.	Calponin-homology (CH) domain-containing protein.	0.754
ENSCSEP00000010489	ENSCSEP00000025343	ENSCSEP00000010489	ENSCSEP00000025343	Lymphocyte cytosolic protein 2a.	Vav 3 guanine nucleotide exchange factor b.	0.754
ENSCSEP00000010489	ENSCSEP00000032733	ENSCSEP00000010489	ENSCSEP00000032733	Lymphocyte cytosolic protein 2a.	Uncharacterized protein.	0.794
ENSCSEP00000010489	FYN	ENSCSEP00000010489	ENSCSEP00000026991	Lymphocyte cytosolic protein 2a.	Tyrosine-protein kinase.	0.582
ENSCSEP00000010489	LOC103378673	ENSCSEP00000010489	ENSCSEP00000004735	Lymphocyte cytosolic protein 2a.	Tyrosine-protein kinase.	0.582
ENSCSEP00000010489	LOC103392516	ENSCSEP00000010489	ENSCSEP00000031987	Lymphocyte cytosolic protein 2a.	GRB2 related adaptor protein 2a.	0.992
ENSCSEP00000010489	LOC103399890	ENSCSEP00000010489	ENSCSEP00000003864	Lymphocyte cytosolic protein 2a.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.794
ENSCSEP00000010489	PLCG1	ENSCSEP00000010489	ENSCSEP00000032738	Lymphocyte cytosolic protein 2a.	Phosphoinositide phospholipase C.	0.794