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PLCG1 PLCG1 CSDE1 CSDE1 LOC103399890 LOC103399890 VAV1 VAV1 LOC103389329 LOC103389329 shc1 shc1 rps27a rps27a tab1 tab1 ENSCSEP00000001095 ENSCSEP00000001095 ikbkg ikbkg ENSCSEP00000000989 ENSCSEP00000000989 ENSCSEP00000000816 ENSCSEP00000000816 ppp3r1 ppp3r1 LOC103399847 LOC103399847 plcg2 plcg2 LOC103377625 LOC103377625 map2k7 map2k7 ENSCSEP00000005585 ENSCSEP00000005585 ENSCSEP00000005592 ENSCSEP00000005592 LOC103379106 LOC103379106 pak2 pak2 ENSCSEP00000006848 ENSCSEP00000006848 vav2 vav2 LOC103379944 LOC103379944 gab2 gab2 map3k20 map3k20 tec tec LOC103380139 LOC103380139 LOC103380153 LOC103380153 kxd1 kxd1 Vpreb3 Vpreb3 ENSCSEP00000009715 ENSCSEP00000009715 LOC103390898 LOC103390898 pak1 pak1 ENSCSEP00000010489 ENSCSEP00000010489 ENSCSEP00000010873 ENSCSEP00000010873 LOC103380750 LOC103380750 LOC103387363 LOC103387363 ENSCSEP00000011946 ENSCSEP00000011946 MAPK1 MAPK1 Jun Jun LOC103398417 LOC103398417 LOC103396229 LOC103396229 LOC103387400 LOC103387400 LOC103388659 LOC103388659 LOC103395725 LOC103395725 PPP3CA PPP3CA LOC103393969 LOC103393969 syk syk LOC103382819 LOC103382819 spns1 spns1 ENSCSEP00000017181 ENSCSEP00000017181 ENSCSEP00000017194 ENSCSEP00000017194 LOC103391026 LOC103391026 ENSCSEP00000018048 ENSCSEP00000018048 nfatc3 nfatc3 LOC103388825 LOC103388825 pdpk1 pdpk1 LOC103381736 LOC103381736 Shc4 Shc4 tab3 tab3 LOC103379440 LOC103379440 LOC103395906 LOC103395906 LOC103392960 LOC103392960 ENSCSEP00000021101 ENSCSEP00000021101 ENSCSEP00000021118 ENSCSEP00000021118 ENSCSEP00000021142 ENSCSEP00000021142 VAV3 VAV3 ENSCSEP00000021357 ENSCSEP00000021357 grb2 grb2 nfatc2 nfatc2 ENSCSEP00000023759 ENSCSEP00000023759 LOC103384301 LOC103384301 tab2 tab2 LOC103391236 LOC103391236 UBB UBB ENSCSEP00000025299 ENSCSEP00000025299 ENSCSEP00000025343 ENSCSEP00000025343 uba52 uba52 ENSCSEP00000025909 ENSCSEP00000025909 LOC103398848 LOC103398848 ENSCSEP00000026745 ENSCSEP00000026745 ENSCSEP00000027518 ENSCSEP00000027518 LOC103393219 LOC103393219 LOC103389156 LOC103389156 map3k7 map3k7 malt1 malt1 LOC103390257 LOC103390257 LOC103380734 LOC103380734 LOC103397828 LOC103397828 LOC103382004 LOC103382004 LOC103399040 LOC103399040 LOC103380804 LOC103380804 ikbkb ikbkb LOC103386737 LOC103386737 LOC103397076 LOC103397076 ENSCSEP00000031177 ENSCSEP00000031177 prkcq prkcq itk itk PAK3 PAK3 LOC103386813 LOC103386813 ENSCSEP00000031686 ENSCSEP00000031686 mapk8 mapk8 MAP2K4 MAP2K4 LOC103392516 LOC103392516 ENSCSEP00000032733 ENSCSEP00000032733 ENSCSEP00000033211 ENSCSEP00000033211 LOC103392680 LOC103392680 ENSCSEP00000033817 ENSCSEP00000033817 harbi1 harbi1 fosl2 fosl2 btk btk map2k4 map2k4 traf6 traf6 Clnk Clnk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLCG1Phosphoinositide phospholipase C. (474 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (917 aa)
LOC1033998901-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1245 aa)
VAV1Vav guanine nucleotide exchange factor 1. (840 aa)
LOC103389329Harbinger transposase derived 1. (338 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (731 aa)
rps27aRibosomal protein S27a. (156 aa)
tab1TGF-beta activated kinase 1/MAP3K7 binding protein 1. (506 aa)
ENSCSEP00000001095Protein phosphatase 3, catalytic subunit, gamma isozyme, b. (462 aa)
ikbkgInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (618 aa)
ENSCSEP00000000989Uncharacterized protein. (1025 aa)
ENSCSEP00000000816WD repeat domain 92. (289 aa)
ppp3r1Protein phosphatase 3 regulatory subunit B, alpha. (170 aa)
LOC103399847V-fos FBJ murine osteosarcoma viral oncogene homolog Aa. (395 aa)
plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1236 aa)
LOC103377625Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (332 aa)
map2k7Mitogen-activated protein kinase kinase 7. (423 aa)
ENSCSEP00000005585Ig-like domain-containing protein. (119 aa)
ENSCSEP00000005592IGv domain-containing protein. (121 aa)
LOC103379106Non-specific serine/threonine protein kinase. (516 aa)
pak2Non-specific serine/threonine protein kinase. (530 aa)
ENSCSEP00000006848Uncharacterized protein. (185 aa)
vav2Vav 2 guanine nucleotide exchange factor. (828 aa)
LOC103379944DDE Tnp4 domain-containing protein. (435 aa)
gab2GRB2-associated binding protein 2. (654 aa)
map3k20Uncharacterized protein. (803 aa)
tecTyrosine-protein kinase. (589 aa)
LOC103380139Nuclear factor of activated T cells 5a. (1505 aa)
LOC103380153Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
kxd1KxDL motif containing 1. (180 aa)
Vpreb3Ig-like domain-containing protein. (122 aa)
ENSCSEP00000009715Ig-like domain-containing protein. (114 aa)
LOC103390898F-box and WD repeat domain containing 11a. (562 aa)
pak1Non-specific serine/threonine protein kinase. (594 aa)
ENSCSEP00000010489Lymphocyte cytosolic protein 2a. (353 aa)
ENSCSEP00000010873CARD domain-containing protein. (157 aa)
LOC103380750Si:ch211-212k18.9. (206 aa)
LOC103387363Mitogen-activated protein kinase. (438 aa)
ENSCSEP00000011946Ig-like domain-containing protein. (110 aa)
MAPK1Mitogen-activated protein kinase 1. (172 aa)
JunJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (303 aa)
LOC103398417Nuclear factor of activated T cells 5b. (1304 aa)
LOC103396229Zgc:162816. (370 aa)
LOC103387400Component of inhibitor of nuclear factor kappa B kinase complex. (741 aa)
LOC103388659RHD domain-containing protein. (938 aa)
LOC103395725Serine/threonine-protein phosphatase. (514 aa)
PPP3CASerine/threonine-protein phosphatase. (523 aa)
LOC103393969Nuclear factor of activated T cells 1. (848 aa)
sykSpleen tyrosine kinase. (651 aa)
LOC103382819UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
spns1Spinster homolog 1 (Drosophila). (511 aa)
ENSCSEP00000017181Uncharacterized protein. (325 aa)
ENSCSEP00000017194Ig-like domain-containing protein. (292 aa)
LOC103391026Mitogen-activated protein kinase. (389 aa)
ENSCSEP00000018048Calponin-homology (CH) domain-containing protein. (83 aa)
nfatc3Nuclear factor of activated T cells 3a. (1118 aa)
LOC103388825Transmembrane protein 176l.4. (239 aa)
pdpk13-phosphoinositide dependent protein kinase 1b. (565 aa)
LOC103381736Uncharacterized protein. (587 aa)
Shc4Uncharacterized protein. (342 aa)
tab3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (614 aa)
LOC103379440MALT paracaspase 3. (572 aa)
LOC103395906Protein kinase domain-containing protein. (659 aa)
LOC103392960Uncharacterized protein. (1003 aa)
ENSCSEP00000021101Uncharacterized protein. (546 aa)
ENSCSEP00000021118Uncharacterized protein. (396 aa)
ENSCSEP00000021142Immunoglobulin heavy variable 11-2. (121 aa)
VAV3Vav guanine nucleotide exchange factor 3. (737 aa)
ENSCSEP00000021357Protein phosphatase 3, catalytic subunit, gamma isozyme, a. (500 aa)
grb2Growth factor receptor-bound protein 2b. (220 aa)
nfatc2Nuclear factor of activated T cells 2a. (949 aa)
ENSCSEP00000023759Ubiquitin-like domain-containing protein. (92 aa)
LOC103384301Transmembrane protein 176. (210 aa)
tab2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (738 aa)
LOC103391236Ankyrin repeat and KH domain containing 1. (2676 aa)
UBBUbiquitin B. (744 aa)
ENSCSEP00000025299Calponin-homology (CH) domain-containing protein. (69 aa)
ENSCSEP00000025343Vav 3 guanine nucleotide exchange factor b. (778 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (151 aa)
ENSCSEP00000025909BZIP domain-containing protein; Belongs to the bZIP family. (326 aa)
LOC103398848Protein kinase domain-containing protein. (770 aa)
ENSCSEP00000026745Serine/threonine-protein phosphatase. (480 aa)
ENSCSEP00000027518Ig-like domain-containing protein. (177 aa)
LOC103393219Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (405 aa)
LOC103389156JunE proto-oncogene, AP-1 transcription factor subunit. (335 aa)
map3k7Mitogen-activated protein kinase kinase kinase 7. (603 aa)
malt1MALT paracaspase 1. (816 aa)
LOC103390257Mitogen-activated protein kinase. (380 aa)
LOC103380734Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (308 aa)
LOC103397828Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa)
LOC103382004DDE Tnp4 domain-containing protein. (370 aa)
LOC103399040Uncharacterized protein. (163 aa)
LOC103380804V-fos FBJ murine osteosarcoma viral oncogene homolog Ab. (380 aa)
ikbkbInhibitor of nuclear factor kappa B kinase subunit beta. (743 aa)
LOC103386737RHD domain-containing protein. (695 aa)
LOC103397076MALT paracaspase 2. (826 aa)
ENSCSEP00000031177DDE Tnp4 domain-containing protein. (415 aa)
prkcqProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (705 aa)
itkTyrosine-protein kinase. (602 aa)
PAK3Non-specific serine/threonine protein kinase. (575 aa)
LOC103386813Uncharacterized protein. (226 aa)
ENSCSEP00000031686Uncharacterized protein. (230 aa)
mapk8Mitogen-activated protein kinase. (383 aa)
MAP2K4Mitogen-activated protein kinase kinase 4. (271 aa)
LOC103392516GRB2 related adaptor protein 2a. (290 aa)
ENSCSEP00000032733Uncharacterized protein. (132 aa)
ENSCSEP00000033211Uncharacterized protein. (89 aa)
LOC103392680Elongin B. (423 aa)
ENSCSEP00000033817Nuclear factor of activated T cells 3b. (899 aa)
harbi1DDE Tnp4 domain-containing protein. (417 aa)
fosl2Fos-like antigen 2. (343 aa)
btkTyrosine-protein kinase. (631 aa)
map2k4Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (399 aa)
traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (576 aa)
ClnkSH2 domain-containing protein. (437 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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