100 items (Cynoglossus semilaevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	spcs1	Signal peptidase complex subunit 1. (159 aa)
	LOC103394985	Exocyst complex component 3-like 2a. (869 aa)
	LOC103387754	Growth hormone. (200 aa)
	ENSCSEP00000026395	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (521 aa)
	exoc6	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (811 aa)
	Slc30a8	Solute carrier family 30 member 8. (373 aa)
	LOC103394760	LIM homeobox 1b. (446 aa)
	AOPEP	Aminopeptidase O (putative). (738 aa)
	dpp9	Dipeptidyl peptidase 9; Belongs to the peptidase S9B family. (854 aa)
	cpe	Carboxypeptidase E. (454 aa)
	sec11a	Signal peptidase complex catalytic subunit SEC11. (179 aa)
	LOC103379386	ISL LIM homeobox 2b. (364 aa)
	ENSCSEP00000019505	Cys_knot domain-containing protein. (123 aa)
	pcsk1	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (784 aa)
	slc30a4	Solute carrier family 30 member 4. (463 aa)
	LOC103382986	Tumor necrosis factor, alpha-induced protein 2b. (682 aa)
	LOC103383003	Exocyst complex component 3-like 4. (757 aa)
	POMC	Proopiomelanocortin. (213 aa)
	ENSCSEP00000012151	Exocyst complex component 4. (919 aa)
	LOC103393629	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
	LOC103380524	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (560 aa)
	cpa6	Carboxypeptidase A6. (405 aa)
	ENSCSEP00000023340	Uncharacterized protein. (565 aa)
	LOC103392320	Granzyme 3, tandem duplicate 4; Belongs to the peptidase S1 family. (259 aa)
	LOC103385288	Uncharacterized protein; Belongs to the peptidase S9B family. (789 aa)
	slc30a6	Solute carrier family 30 member 6. (556 aa)
	dpp10	Uncharacterized protein; Belongs to the peptidase S9B family. (719 aa)
	ENSCSEP00000023925	TGF_BETA_2 domain-containing protein. (351 aa)
	p4hb	Protein disulfide-isomerase. (511 aa)
	ENSCSEP00000024165	Exocyst complex component 3-like 2b. (860 aa)
	LOC103386559	Cys_knot domain-containing protein. (152 aa)
	Inhbb	Inhibin subunit beta B. (577 aa)
	pcsk2	Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family. (641 aa)
	MME	Membrane metalloendopeptidase. (770 aa)
	spcs3	Signal peptidase complex subunit 3. (180 aa)
	slc30a5	Solute carrier family 30 member 5. (579 aa)
	atp6ap2	ATPase H+ transporting accessory protein 2. (376 aa)
	isl2	ISL LIM homeobox 2a. (402 aa)
	LOC103396957	Uncharacterized protein. (318 aa)
	LOC103379249	Si:ch211-71n6.4. (590 aa)
	isl1	ISL LIM homeobox 1. (349 aa)
	LOC103389823	TGF_BETA_2 domain-containing protein. (397 aa)
	cpb2	Carboxypeptidase B2 (plasma). (423 aa)
	GPR119	G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. (391 aa)
	LOC103392157	Fibroblast activation protein, alpha; Belongs to the peptidase S9B family. (744 aa)
	gcg	Glucagon b. (123 aa)
	ENSCSEP00000016487	Caudal type homeobox 1a. (117 aa)
	INHBC	Inhibin subunit beta C. (368 aa)
	ENSCSEP00000017533	RabBD domain-containing protein. (138 aa)
	myrip	Myosin VIIA and Rab interacting protein. (853 aa)
	exoc7	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (712 aa)
	cga	Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (139 aa)
	LOC103379920	Exocyst complex component 3-like 1. (731 aa)
	LOC103386947	Luteinizing hormone, beta polypeptide. (158 aa)
	ace2	Angiotensin-converting enzyme. (802 aa)
	ENSCSEP00000001370	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (765 aa)
	dpp6	Dipeptidyl-peptidase 6a; Belongs to the peptidase S9B family. (851 aa)
	phex	Phosphate regulating endopeptidase homolog, X-linked. (751 aa)
	slc30a7	Solute carrier family 30 member 7. (373 aa)
	exoc2	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (945 aa)
	LOC103385643	Guanine nucleotide binding protein (G protein), beta polypeptide 1b. (340 aa)
	mmel1	Membrane metallo-endopeptidase-like 1. (898 aa)
	LOC103396679	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (346 aa)
	exoc3	Exocyst complex component 3. (751 aa)
	ENSCSEP00000032318	Caudal type homeobox 1 b. (307 aa)
	LOC103380837	Uncharacterized protein. (238 aa)
	cltrn	Collectrin domain-containing protein. (212 aa)
	Gnb3	Guanine nucleotide binding protein (G protein), beta polypeptide 3a. (307 aa)
	grp	Uncharacterized protein. (164 aa)
	ace	Angiotensin-converting enzyme. (1286 aa)
	LOC103380727	Platelet-activating factor acetylhydrolase. (429 aa)
	LOC103377348	TGF_BETA_2 domain-containing protein. (406 aa)
	LOC103395950	Uncharacterized protein; Belongs to the peptidase S9B family. (890 aa)
	exoc5	Exocyst complex component 5. (708 aa)
	LOC103396168	Dipeptidyl-peptidase 6b; Belongs to the peptidase S9B family. (788 aa)
	LOC103377267	Carboxypeptidase B1 (tissue). (416 aa)
	LOC103393769	POMC-b. (178 aa)
	ENSCSEP00000027967	FYVE_2 domain-containing protein. (141 aa)
	ENSCSEP00000003903	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (321 aa)
	agt	Angiotensinogen; Belongs to the serpin family. (461 aa)
	enpep	Aminopeptidase. (954 aa)
	exoc8	Exocyst complex component 8. (686 aa)
	exoc1	Exocyst complex component 1. (927 aa)
	LOC103383597	Protein disulfide-isomerase. (570 aa)
	gnb1	Guanine nucleotide binding protein (G protein), beta polypeptide 1a. (340 aa)
	ALX3	ALX homeobox 3. (399 aa)
	ctsz	Cathepsin Z; Belongs to the peptidase C1 family. (309 aa)
	LOC103384813	Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2. (350 aa)
	LOC103380098	Leptin A. (160 aa)
	LOC103390711	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (347 aa)
	cdx4	Caudal type homeobox 4. (271 aa)
	GCG	Glucagon. (168 aa)
	LOC103389443	Dipeptidyl-peptidase 4; Belongs to the peptidase S9B family. (741 aa)
	cpo	Carboxypeptidase O. (360 aa)
	inha	Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (343 aa)
	spcs2	Signal peptidase complex subunit 2. (212 aa)
	LOC103389598	Uncharacterized protein; Belongs to the peptidase S9B family. (794 aa)
	ins	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (113 aa)
	ENSCSEP00000011141	DPPIV_N domain-containing protein. (115 aa)
	LOC103399339	TGF_BETA_2 domain-containing protein. (126 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOPEP	agt	ENSCSEP00000018091	ENSCSEP00000004492	Aminopeptidase O (putative).	Angiotensinogen; Belongs to the serpin family.	0.728
ENSCSEP00000001370	ENSCSEP00000003903	ENSCSEP00000001370	ENSCSEP00000003903	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	0.961
ENSCSEP00000001370	ENSCSEP00000012151	ENSCSEP00000001370	ENSCSEP00000012151	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Exocyst complex component 4.	0.979
ENSCSEP00000001370	ENSCSEP00000024165	ENSCSEP00000001370	ENSCSEP00000024165	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Exocyst complex component 3-like 2b.	0.866
ENSCSEP00000001370	LOC103379920	ENSCSEP00000001370	ENSCSEP00000003020	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Exocyst complex component 3-like 1.	0.957
ENSCSEP00000001370	LOC103382986	ENSCSEP00000001370	ENSCSEP00000020961	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Tumor necrosis factor, alpha-induced protein 2b.	0.866
ENSCSEP00000001370	LOC103383003	ENSCSEP00000001370	ENSCSEP00000020967	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Exocyst complex component 3-like 4.	0.875
ENSCSEP00000001370	LOC103394985	ENSCSEP00000001370	ENSCSEP00000027878	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Exocyst complex component 3-like 2a.	0.866
ENSCSEP00000001370	exoc1	ENSCSEP00000001370	ENSCSEP00000005686	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Exocyst complex component 1.	0.980
ENSCSEP00000001370	exoc2	ENSCSEP00000001370	ENSCSEP00000000495	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	0.979
ENSCSEP00000001370	exoc3	ENSCSEP00000001370	ENSCSEP00000032961	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Exocyst complex component 3.	0.957
ENSCSEP00000001370	exoc5	ENSCSEP00000001370	ENSCSEP00000000412	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Exocyst complex component 5.	0.979
ENSCSEP00000001370	exoc7	ENSCSEP00000001370	ENSCSEP00000003871	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	0.961
ENSCSEP00000001370	exoc8	ENSCSEP00000001370	ENSCSEP00000004928	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Exocyst complex component 8.	0.979
ENSCSEP00000003903	ENSCSEP00000001370	ENSCSEP00000003903	ENSCSEP00000001370	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	0.961
ENSCSEP00000003903	ENSCSEP00000012151	ENSCSEP00000003903	ENSCSEP00000012151	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Exocyst complex component 4.	0.982
ENSCSEP00000003903	ENSCSEP00000024165	ENSCSEP00000003903	ENSCSEP00000024165	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Exocyst complex component 3-like 2b.	0.869
ENSCSEP00000003903	LOC103379920	ENSCSEP00000003903	ENSCSEP00000003020	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Exocyst complex component 3-like 1.	0.919
ENSCSEP00000003903	LOC103382986	ENSCSEP00000003903	ENSCSEP00000020961	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Tumor necrosis factor, alpha-induced protein 2b.	0.869
ENSCSEP00000003903	LOC103383003	ENSCSEP00000003903	ENSCSEP00000020967	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Exocyst complex component 3-like 4.	0.869