STRINGSTRING
LOC103385488 LOC103385488 toe1 toe1 Cnot1 Cnot1 ENSCSEP00000033498 ENSCSEP00000033498 pan2 pan2 ENSCSEP00000026776 ENSCSEP00000026776 eif4a2 eif4a2 LOC103393786 LOC103393786 ENSCSEP00000026459 ENSCSEP00000026459 LOC103391261 LOC103391261 c4h19orf54 c4h19orf54 dcp2 dcp2 tent2 tent2 ENSCSEP00000025902 ENSCSEP00000025902 LOC103390172 LOC103390172 pan3 pan3 cnot9 cnot9 lsm4 lsm4 cnot2 cnot2 Cnot2 Cnot2 ttc37 ttc37 lsm5 lsm5 LOC103394269 LOC103394269 cnot4 cnot4 lsm3 lsm3 lsm7 lsm7 eif4a1 eif4a1 exosc9 exosc9 exosc6 exosc6 edc4 edc4 cnot6l cnot6l pabpc1 pabpc1 edc3 edc3 Tut1 Tut1 skiv2l skiv2l exosc7 exosc7 LOC103390988 LOC103390988 exosc4 exosc4 lsm1 lsm1 cnot10 cnot10 LOC103397020 LOC103397020 LOC103393952 LOC103393952 LOC103397001 LOC103397001 Patl2 Patl2 Dcp1b Dcp1b LOC103396910 LOC103396910 patl1 patl1 dis3l dis3l exosc1 exosc1 ENSCSEP00000011914 ENSCSEP00000011914 exosc5 exosc5 TUT7 TUT7 mtpap mtpap ENSCSEP00000011006 ENSCSEP00000011006 ENSCSEP00000010999 ENSCSEP00000010999 ddx6 ddx6 LOC103387320 LOC103387320 exosc3 exosc3 eif4b eif4b cnot3 cnot3 LOC103390638 LOC103390638 wdr61 wdr61 dis3 dis3 lsm2 lsm2 hbs1l hbs1l TUT4 TUT4 ENSCSEP00000003783 ENSCSEP00000003783 ENSCSEP00000003777 ENSCSEP00000003777 ENSCSEP00000003772 ENSCSEP00000003772 parn parn lsm6 lsm6 ENSCSEP00000000582 ENSCSEP00000000582 pabpc4 pabpc4 LOC103379348 LOC103379348 LOC103391308 LOC103391308 dis3l2 dis3l2 exosc8 exosc8 LOC103397741 LOC103397741 LOC103383092 LOC103383092 cnot8 cnot8 Cnot11 Cnot11 eif4a3 eif4a3
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103385488Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (554 aa)
toe1Target of EGR1, exonuclease. (527 aa)
Cnot1CCR4-NOT transcription complex, subunit 1. (829 aa)
ENSCSEP00000033498CCR4-NOT transcription complex, subunit 1. (1499 aa)
pan2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1195 aa)
ENSCSEP00000026776Uncharacterized protein. (180 aa)
eif4a2Eukaryotic translation initiation factor 4A, isoform 2; Belongs to the DEAD box helicase family. (440 aa)
LOC103393786CCR4-NOT transcription complex, subunit 3b. (873 aa)
ENSCSEP00000026459Uncharacterized protein. (337 aa)
LOC103391261Decapping enzyme, scavenger. (330 aa)
c4h19orf54Zgc:153119. (306 aa)
dcp2Decapping mRNA 2. (390 aa)
tent2Terminal nucleotidyltransferase 2. (475 aa)
ENSCSEP00000025902Exosome component 2. (135 aa)
LOC103390172Exosome component 2. (291 aa)
pan3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (794 aa)
cnot9CCR4-NOT transcription complex subunit 9. (299 aa)
lsm4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (142 aa)
cnot2CCR4-NOT transcription complex, subunit 2. (484 aa)
Cnot2Uncharacterized protein. (75 aa)
ttc37Tetratricopeptide repeat domain 37. (1765 aa)
lsm5LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated. (59 aa)
LOC103394269Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (633 aa)
cnot4CCR4-NOT transcription complex, subunit 4a. (838 aa)
lsm3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (133 aa)
lsm7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (120 aa)
eif4a1Eukaryotic translation initiation factor 4A1B; Belongs to the DEAD box helicase family. (402 aa)
exosc9Exosome component 9. (400 aa)
exosc6Exosome component 6. (270 aa)
edc4Enhancer of mRNA decapping 4. (1397 aa)
cnot6lCCR4-NOT transcription complex, subunit 6-like. (553 aa)
pabpc1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (632 aa)
edc3Enhancer of mRNA decapping 3 homolog (S. cerevisiae). (478 aa)
Tut1Terminal uridylyl transferase 1, U6 snRNA-specific. (791 aa)
skiv2lSKI2 homolog, superkiller viralicidic activity 2-like. (1234 aa)
exosc7Exosome component 7. (291 aa)
LOC103390988CCR4-NOT transcription complex, subunit 6a. (559 aa)
exosc4Exosome component 4. (245 aa)
lsm1U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (145 aa)
cnot10CCR4-NOT transcription complex, subunit 10. (735 aa)
LOC103397020Endo/exonuclease/phosphatase domain-containing protein. (426 aa)
LOC103393952Uncharacterized protein; Belongs to the DEAD box helicase family. (489 aa)
LOC103397001Poly(A) binding protein interacting protein 1. (411 aa)
Patl2PAT1 homolog 2. (676 aa)
Dcp1bDecapping mRNA 1B. (646 aa)
LOC103396910U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (184 aa)
patl1PAT1 homolog 1, processing body mRNA decay factor. (833 aa)
dis3lDIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1047 aa)
exosc1Exosome component 1. (175 aa)
ENSCSEP00000011914Q_MOTIF domain-containing protein. (74 aa)
exosc5Exosome component 5. (219 aa)
TUT7Terminal uridylyl transferase 7. (725 aa)
mtpapMitochondrial poly(A) polymerase. (563 aa)
ENSCSEP00000011006Uncharacterized protein. (147 aa)
ENSCSEP00000010999C2H2-type domain-containing protein. (213 aa)
ddx6DEAD (Asp-Glu-Ala-Asp) box helicase 6; Belongs to the DEAD box helicase family. (482 aa)
LOC103387320Eukaryotic translation initiation factor 4E family member 1c; Belongs to the eukaryotic initiation factor 4E family. (215 aa)
exosc3Exosome component 3. (244 aa)
eif4bEukaryotic translation initiation factor 4Bb. (658 aa)
cnot3CCR4-NOT transcription complex, subunit 3a. (922 aa)
LOC103390638Eukaryotic translation initiation factor 4ea; Belongs to the eukaryotic initiation factor 4E family. (252 aa)
wdr61WD repeat domain 61. (276 aa)
dis3DIS3 exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (948 aa)
lsm2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
hbs1lHBS1-like translational GTPase. (868 aa)
TUT4Terminal uridylyl transferase 4. (662 aa)
ENSCSEP00000003783Uncharacterized protein. (122 aa)
ENSCSEP00000003777Uncharacterized protein. (152 aa)
ENSCSEP00000003772Uncharacterized protein. (193 aa)
parnPoly(A)-specific ribonuclease (deadenylation nuclease). (692 aa)
lsm6LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (98 aa)
ENSCSEP00000000582Uncharacterized protein. (140 aa)
pabpc4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (627 aa)
LOC103379348Eukaryotic translation initiation factor 4eb; Belongs to the eukaryotic initiation factor 4E family. (232 aa)
LOC103391308CCR4-NOT transcription complex, subunit 7. (286 aa)
dis3l2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1034 aa)
exosc8Exosome component 8. (277 aa)
LOC103397741Poly(A) binding protein interacting protein 1. (429 aa)
LOC103383092NOT2_3_5 domain-containing protein. (564 aa)
cnot8CCR4-NOT transcription complex, subunit 8. (286 aa)
Cnot11CCR4-NOT transcription complex, subunit 11. (430 aa)
eif4a3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (406 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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