26 items (Cynoglossus semilaevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	lgr4	Leucine-rich repeat containing G protein-coupled receptor 4. (986 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	lrtm1	Leucine rich repeats and transmembrane domains 1. (393 aa)
	lrp4	Low density lipoprotein receptor-related protein 4. (1912 aa)
	fzd5	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
	lrp6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1621 aa)
	LOC103396896	RING-type domain-containing protein. (872 aa)
	rspo3	R-spondin 3. (330 aa)
	rspo2	R-spondin2. (244 aa)
	rnf43	RING-type domain-containing protein. (829 aa)
	fzd8	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (551 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
	usp8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1087 aa)
	fzd6	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (693 aa)
	ENSCSEP00000023759	Ubiquitin-like domain-containing protein. (92 aa)
	ENSCSEP00000023957	R-spondin 4. (209 aa)
	UBB	Ubiquitin B. (744 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (151 aa)
	ENSCSEP00000028399	LRRNT domain-containing protein. (580 aa)
	ENSCSEP00000028619	G_PROTEIN_RECEP_F1_2 domain-containing protein. (792 aa)
	fzd4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (533 aa)
	LOC103399030	Uncharacterized protein. (388 aa)
	rspo1	R-spondin1 protein. (277 aa)
	LOC103397863	Zinc and ring finger 3. (894 aa)
	LOC103379514	Low density lipoprotein receptor-related protein 5. (1626 aa)
	FZD8	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCSEP00000023759	LOC103396896	ENSCSEP00000023759	ENSCSEP00000012132	Ubiquitin-like domain-containing protein.	RING-type domain-containing protein.	0.616
ENSCSEP00000023759	LOC103397863	ENSCSEP00000023759	ENSCSEP00000032620	Ubiquitin-like domain-containing protein.	Zinc and ring finger 3.	0.616
ENSCSEP00000023759	UBB	ENSCSEP00000023759	ENSCSEP00000025180	Ubiquitin-like domain-containing protein.	Ubiquitin B.	0.961
ENSCSEP00000023759	rnf43	ENSCSEP00000023759	ENSCSEP00000016923	Ubiquitin-like domain-containing protein.	RING-type domain-containing protein.	0.670
ENSCSEP00000023759	rps27a	ENSCSEP00000023759	ENSCSEP00000002392	Ubiquitin-like domain-containing protein.	Ribosomal protein S27a.	0.990
ENSCSEP00000023759	usp8	ENSCSEP00000023759	ENSCSEP00000019475	Ubiquitin-like domain-containing protein.	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.	0.866
ENSCSEP00000023957	ENSCSEP00000028619	ENSCSEP00000023957	ENSCSEP00000028619	R-spondin 4.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.959
ENSCSEP00000023957	LOC103396896	ENSCSEP00000023957	ENSCSEP00000012132	R-spondin 4.	RING-type domain-containing protein.	0.942
ENSCSEP00000023957	LOC103397863	ENSCSEP00000023957	ENSCSEP00000032620	R-spondin 4.	Zinc and ring finger 3.	0.942
ENSCSEP00000023957	lgr4	ENSCSEP00000023957	ENSCSEP00000001845	R-spondin 4.	Leucine-rich repeat containing G protein-coupled receptor 4.	0.959
ENSCSEP00000023957	rnf43	ENSCSEP00000023957	ENSCSEP00000016923	R-spondin 4.	RING-type domain-containing protein.	0.945
ENSCSEP00000028399	LOC103399030	ENSCSEP00000028399	ENSCSEP00000030126	LRRNT domain-containing protein.	Uncharacterized protein.	0.858
ENSCSEP00000028399	rnf43	ENSCSEP00000028399	ENSCSEP00000016923	LRRNT domain-containing protein.	RING-type domain-containing protein.	0.442
ENSCSEP00000028399	rspo1	ENSCSEP00000028399	ENSCSEP00000031665	LRRNT domain-containing protein.	R-spondin1 protein.	0.643
ENSCSEP00000028619	ENSCSEP00000023957	ENSCSEP00000028619	ENSCSEP00000023957	G_PROTEIN_RECEP_F1_2 domain-containing protein.	R-spondin 4.	0.959
ENSCSEP00000028619	LOC103396896	ENSCSEP00000028619	ENSCSEP00000012132	G_PROTEIN_RECEP_F1_2 domain-containing protein.	RING-type domain-containing protein.	0.801
ENSCSEP00000028619	LOC103397863	ENSCSEP00000028619	ENSCSEP00000032620	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Zinc and ring finger 3.	0.801
ENSCSEP00000028619	UBB	ENSCSEP00000028619	ENSCSEP00000025180	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Ubiquitin B.	0.504
ENSCSEP00000028619	lgr4	ENSCSEP00000028619	ENSCSEP00000001845	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Leucine-rich repeat containing G protein-coupled receptor 4.	0.932
ENSCSEP00000028619	rnf43	ENSCSEP00000028619	ENSCSEP00000016923	G_PROTEIN_RECEP_F1_2 domain-containing protein.	RING-type domain-containing protein.	0.849