45 items (Cynoglossus semilaevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rps27a	Ribosomal protein S27a. (156 aa)
	ENSCSEP00000033458	Fibroblast growth factor receptor substrate 2b. (492 aa)
	FGF6-2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (278 aa)
	LOC103397742	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
	mknk1	MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (464 aa)
	LOC103386740	Tyrosine-protein kinase. (558 aa)
	ENSCSEP00000029949	Uncharacterized protein. (244 aa)
	LOC103397828	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa)
	LOC103378498	Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
	LOC103389109	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (359 aa)
	LOC103393219	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (405 aa)
	LOC103395232	Anosmin 1b. (674 aa)
	LOC103391274	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (393 aa)
	fgf8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	mknk2	MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (475 aa)
	LOC103395395	Uncharacterized protein. (869 aa)
	ENSCSEP00000025543	Fibroblast growth factor receptor. (675 aa)
	cbl	Cbl proto-oncogene, E3 ubiquitin protein ligase. (952 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (151 aa)
	UBB	Ubiquitin B. (744 aa)
	fgf5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (235 aa)
	LOC103391208	Serine/threonine-protein phosphatase. (309 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)
	LOC103391194	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (156 aa)
	ENSCSEP00000023759	Ubiquitin-like domain-containing protein. (92 aa)
	cblc	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (550 aa)
	LOC103385228	Tyrosine-protein kinase. (551 aa)
	grb2	Growth factor receptor-bound protein 2b. (220 aa)
	ENSCSEP00000020731	Anosmin 1a. (409 aa)
	LOC103384120	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
	LOC103395214	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (149 aa)
	ppp2cb	Serine/threonine-protein phosphatase. (309 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
	ANOS1	Anosmin 1. (675 aa)
	Spry2	Sprouty RTK signaling antagonist 2. (418 aa)
	ENSCSEP00000012109	Metallophos domain-containing protein. (79 aa)
	MAPK1	Mitogen-activated protein kinase 1. (172 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1276 aa)
	fgf4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
	fgf3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (248 aa)
	fgf23	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (265 aa)
	FGF6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (185 aa)
	fgf2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (1205 aa)
	LOC103399916	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANOS1	ENSCSEP00000025543	ENSCSEP00000014994	ENSCSEP00000025543	Anosmin 1.	Fibroblast growth factor receptor.	0.593
ANOS1	ENSCSEP00000029949	ENSCSEP00000014994	ENSCSEP00000029949	Anosmin 1.	Uncharacterized protein.	0.593
ANOS1	LOC103384120	ENSCSEP00000014994	ENSCSEP00000019883	Anosmin 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.471
ANOS1	LOC103391194	ENSCSEP00000014994	ENSCSEP00000023803	Anosmin 1.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.471
ANOS1	LOC103391274	ENSCSEP00000014994	ENSCSEP00000027035	Anosmin 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.471
ANOS1	LOC103395214	ENSCSEP00000014994	ENSCSEP00000018906	Anosmin 1.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.471
ANOS1	fgf2	ENSCSEP00000014994	ENSCSEP00000006974	Anosmin 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.454
ANOS1	fgf23	ENSCSEP00000014994	ENSCSEP00000010801	Anosmin 1.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.533
ANOS1	fgf4	ENSCSEP00000014994	ENSCSEP00000010997	Anosmin 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.523
ANOS1	fgf5	ENSCSEP00000014994	ENSCSEP00000024357	Anosmin 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.429
ENSCSEP00000012109	ENSCSEP00000023759	ENSCSEP00000012109	ENSCSEP00000023759	Metallophos domain-containing protein.	Ubiquitin-like domain-containing protein.	0.603
ENSCSEP00000012109	LOC103378498	ENSCSEP00000012109	ENSCSEP00000028334	Metallophos domain-containing protein.	Protein phosphatase 2, regulatory subunit A, beta b.	0.947
ENSCSEP00000012109	LOC103393219	ENSCSEP00000012109	ENSCSEP00000027614	Metallophos domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.442
ENSCSEP00000012109	LOC103397828	ENSCSEP00000012109	ENSCSEP00000029876	Metallophos domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.442
ENSCSEP00000012109	MAPK1	ENSCSEP00000012109	ENSCSEP00000011950	Metallophos domain-containing protein.	Mitogen-activated protein kinase 1.	0.442
ENSCSEP00000012109	Spry2	ENSCSEP00000012109	ENSCSEP00000014660	Metallophos domain-containing protein.	Sprouty RTK signaling antagonist 2.	0.458
ENSCSEP00000012109	UBB	ENSCSEP00000012109	ENSCSEP00000025180	Metallophos domain-containing protein.	Ubiquitin B.	0.532
ENSCSEP00000012109	grb2	ENSCSEP00000012109	ENSCSEP00000022549	Metallophos domain-containing protein.	Growth factor receptor-bound protein 2b.	0.506
ENSCSEP00000012109	rps27a	ENSCSEP00000012109	ENSCSEP00000002392	Metallophos domain-containing protein.	Ribosomal protein S27a.	0.515
ENSCSEP00000012109	uba52	ENSCSEP00000012109	ENSCSEP00000025345	Metallophos domain-containing protein.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.521