38 items (Cynoglossus semilaevis) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:
	ENSCSEP00000033458	Fibroblast growth factor receptor substrate 2b. (492 aa)
	LOC103395214	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (149 aa)
	LOC103384120	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
	grb2	Growth factor receptor-bound protein 2b. (220 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	LOC103385228	Tyrosine-protein kinase. (551 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (1205 aa)
	fgf2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	LOC103390704	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
	LOC103390897	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (211 aa)
	FGF6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (185 aa)
	fgf23	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (265 aa)
	fgf4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
	fgf19	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1276 aa)
	MAPK1	Mitogen-activated protein kinase 1. (172 aa)
	ENSCSEP00000012109	Metallophos domain-containing protein. (79 aa)
	Spry2	Sprouty RTK signaling antagonist 2. (418 aa)
	ppp2cb	Serine/threonine-protein phosphatase. (309 aa)
	fgf16	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
	cblc	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (550 aa)
	ENSCSEP00000023759	Ubiquitin-like domain-containing protein. (92 aa)
	LOC103391194	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (156 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)
	LOC103391208	Serine/threonine-protein phosphatase. (309 aa)
	UBB	Ubiquitin B. (744 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (151 aa)
	cbl	Cbl proto-oncogene, E3 ubiquitin protein ligase. (952 aa)
	LOC103395395	Uncharacterized protein. (869 aa)
	mknk2	MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (475 aa)
	fgf8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	LOC103391274	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (393 aa)
	LOC103393219	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (405 aa)
	LOC103378498	Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
	LOC103397828	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa)
	LOC103386740	Tyrosine-protein kinase. (558 aa)
	mknk1	MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (464 aa)
	FGF6-2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (278 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCSEP00000012109	ENSCSEP00000023759	ENSCSEP00000012109	ENSCSEP00000023759	Metallophos domain-containing protein.	Ubiquitin-like domain-containing protein.	0.603
ENSCSEP00000012109	LOC103378498	ENSCSEP00000012109	ENSCSEP00000028334	Metallophos domain-containing protein.	Protein phosphatase 2, regulatory subunit A, beta b.	0.947
ENSCSEP00000012109	LOC103393219	ENSCSEP00000012109	ENSCSEP00000027614	Metallophos domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.442
ENSCSEP00000012109	LOC103397828	ENSCSEP00000012109	ENSCSEP00000029876	Metallophos domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.442
ENSCSEP00000012109	MAPK1	ENSCSEP00000012109	ENSCSEP00000011950	Metallophos domain-containing protein.	Mitogen-activated protein kinase 1.	0.442
ENSCSEP00000012109	Spry2	ENSCSEP00000012109	ENSCSEP00000014660	Metallophos domain-containing protein.	Sprouty RTK signaling antagonist 2.	0.458
ENSCSEP00000012109	UBB	ENSCSEP00000012109	ENSCSEP00000025180	Metallophos domain-containing protein.	Ubiquitin B.	0.532
ENSCSEP00000012109	grb2	ENSCSEP00000012109	ENSCSEP00000022549	Metallophos domain-containing protein.	Growth factor receptor-bound protein 2b.	0.506
ENSCSEP00000012109	rps27a	ENSCSEP00000012109	ENSCSEP00000002392	Metallophos domain-containing protein.	Ribosomal protein S27a.	0.515
ENSCSEP00000012109	uba52	ENSCSEP00000012109	ENSCSEP00000025345	Metallophos domain-containing protein.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.521
ENSCSEP00000023759	ENSCSEP00000012109	ENSCSEP00000023759	ENSCSEP00000012109	Ubiquitin-like domain-containing protein.	Metallophos domain-containing protein.	0.603
ENSCSEP00000023759	LOC103378498	ENSCSEP00000023759	ENSCSEP00000028334	Ubiquitin-like domain-containing protein.	Protein phosphatase 2, regulatory subunit A, beta b.	0.592
ENSCSEP00000023759	LOC103390704	ENSCSEP00000023759	ENSCSEP00000007011	Ubiquitin-like domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.400
ENSCSEP00000023759	LOC103390897	ENSCSEP00000023759	ENSCSEP00000009982	Ubiquitin-like domain-containing protein.	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.	0.400
ENSCSEP00000023759	LOC103391194	ENSCSEP00000023759	ENSCSEP00000023803	Ubiquitin-like domain-containing protein.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.400
ENSCSEP00000023759	LOC103391208	ENSCSEP00000023759	ENSCSEP00000024173	Ubiquitin-like domain-containing protein.	Serine/threonine-protein phosphatase.	0.605
ENSCSEP00000023759	LOC103393219	ENSCSEP00000023759	ENSCSEP00000027614	Ubiquitin-like domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.404
ENSCSEP00000023759	LOC103395214	ENSCSEP00000023759	ENSCSEP00000018906	Ubiquitin-like domain-containing protein.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.400
ENSCSEP00000023759	LOC103395395	ENSCSEP00000023759	ENSCSEP00000025865	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.671
ENSCSEP00000023759	LOC103397828	ENSCSEP00000023759	ENSCSEP00000029876	Ubiquitin-like domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.404