STRINGSTRING
flrt3 flrt3 ENSCSEP00000033458 ENSCSEP00000033458 FGF6-2 FGF6-2 gab1 gab1 PLCG1 PLCG1 ENSCSEP00000032733 ENSCSEP00000032733 LOC103397742 LOC103397742 mknk1 mknk1 LOC103386740 LOC103386740 PIK3CA PIK3CA ENSCSEP00000029949 ENSCSEP00000029949 LOC103397828 LOC103397828 flrt2 flrt2 LOC103378498 LOC103378498 LOC103389109 LOC103389109 LOC103393219 LOC103393219 LOC103395232 LOC103395232 LOC103391274 LOC103391274 LOC103396148 LOC103396148 fgf8 fgf8 mknk2 mknk2 LOC103395395 LOC103395395 ENSCSEP00000025543 ENSCSEP00000025543 cbl cbl uba52 uba52 UBB UBB fgf5 fgf5 LOC103394884 LOC103394884 LOC103391208 LOC103391208 ppp2ca ppp2ca LOC103391194 LOC103391194 ENSCSEP00000023759 ENSCSEP00000023759 cblc cblc LOC103385228 LOC103385228 grb2 grb2 LOC103392975 LOC103392975 ENSCSEP00000020731 ENSCSEP00000020731 Shc4 Shc4 LOC103384120 LOC103384120 LOC103395214 LOC103395214 ppp2cb ppp2cb FGF10 FGF10 ANOS1 ANOS1 Spry2 Spry2 hras hras ENSCSEP00000012109 ENSCSEP00000012109 MAPK1 MAPK1 ENSCSEP00000011448 ENSCSEP00000011448 fndc3a fndc3a fgf4 fgf4 fgf3 fgf3 fgf23 fgf23 FGF6 FGF6 LOC103390897 LOC103390897 LOC103390821 LOC103390821 kras kras spred1 spred1 LOC103390704 LOC103390704 fgf2 fgf2 spred2 spred2 LOC103390636 LOC103390636 fndc3b fndc3b LOC103399916 LOC103399916 CSDE1 CSDE1 shc1 shc1 rps27a rps27a LOC103385760 LOC103385760 FGFRL1 FGFRL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
flrt3Fibronectin leucine rich transmembrane 3. (649 aa)
ENSCSEP00000033458Fibroblast growth factor receptor substrate 2b. (492 aa)
FGF6-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (278 aa)
gab1GRB2-associated binding protein 1. (835 aa)
PLCG1Phosphoinositide phospholipase C. (474 aa)
ENSCSEP00000032733Uncharacterized protein. (132 aa)
LOC103397742Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
mknk1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (464 aa)
LOC103386740Tyrosine-protein kinase. (558 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ENSCSEP00000029949Uncharacterized protein. (244 aa)
LOC103397828Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa)
flrt2Fibronectin leucine rich transmembrane protein 2. (664 aa)
LOC103378498Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
LOC103389109Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (359 aa)
LOC103393219Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (405 aa)
LOC103395232Anosmin 1b. (674 aa)
LOC103391274Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (393 aa)
LOC103396148Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
mknk2MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (475 aa)
LOC103395395Uncharacterized protein. (869 aa)
ENSCSEP00000025543Fibroblast growth factor receptor. (675 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (952 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (151 aa)
UBBUbiquitin B. (744 aa)
fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (235 aa)
LOC103394884Fibronectin type-III domain-containing protein. (682 aa)
LOC103391208Serine/threonine-protein phosphatase. (309 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
LOC103391194Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (156 aa)
ENSCSEP00000023759Ubiquitin-like domain-containing protein. (92 aa)
cblcCbl proto-oncogene C, E3 ubiquitin protein ligase. (550 aa)
LOC103385228Tyrosine-protein kinase. (551 aa)
grb2Growth factor receptor-bound protein 2b. (220 aa)
LOC103392975Zgc:55558. (187 aa)
ENSCSEP00000020731Anosmin 1a. (409 aa)
Shc4Uncharacterized protein. (342 aa)
LOC103384120Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
LOC103395214Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (149 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
ANOS1Anosmin 1. (675 aa)
Spry2Sprouty RTK signaling antagonist 2. (418 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
ENSCSEP00000012109Metallophos domain-containing protein. (79 aa)
MAPK1Mitogen-activated protein kinase 1. (172 aa)
ENSCSEP00000011448PI3K-ABD domain-containing protein; Belongs to the PI3/PI4-kinase family. (123 aa)
fndc3aFibronectin type III domain containing 3A. (1276 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (248 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (265 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (185 aa)
LOC103390897Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (211 aa)
LOC103390821Fibronectin leucine rich transmembrane protein 1b. (635 aa)
krasV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
spred1Sprouty related EVH1 domain containing 1. (436 aa)
LOC103390704Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
spred2Sprouty related EVH1 domain containing 2b. (463 aa)
LOC103390636Fibroblast growth factor receptor like 1a. (499 aa)
fndc3bFibronectin type III domain containing 3Ba. (1205 aa)
LOC103399916Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (917 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (731 aa)
rps27aRibosomal protein S27a. (156 aa)
LOC103385760Fibroblast growth factor receptor substrate 3. (616 aa)
FGFRL1Fibroblast growth factor receptor like 1. (496 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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