70 items (Cynoglossus semilaevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Polk	Polymerase (DNA directed) kappa. (867 aa)
	rfc4	Replication factor C (activator 1) 4. (358 aa)
	LOC103383408	Uncharacterized protein. (551 aa)
	meiob	Methionine sulfoxide reductase B1b. (436 aa)
	Polh	Polymerase (DNA directed), eta. (294 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	LOC103383434	Uncharacterized protein. (612 aa)
	usp10	Ubiquitin carboxyl-terminal hydrolase. (879 aa)
	usp43	Ubiquitin specific peptidase 43a; Belongs to the peptidase C19 family. (1233 aa)
	rev1	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1175 aa)
	pole2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
	RCBTB1	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (637 aa)
	rfc1	Replication factor C subunit 1. (1083 aa)
	LOC103388454	Uncharacterized protein. (597 aa)
	pole3	Polymerase (DNA directed), epsilon 3 (p17 subunit). (149 aa)
	kxd1	KxDL motif containing 1. (180 aa)
	ENSCSEP00000009964	Uncharacterized protein. (85 aa)
	LOC103387326	FinTRIM family, member 14-like. (587 aa)
	Pold2	Uncharacterized protein. (78 aa)
	rcbtb2	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (554 aa)
	ENSCSEP00000011469	Uncharacterized protein. (217 aa)
	ENSCSEP00000011696	Uncharacterized protein. (103 aa)
	LOC103399484	Uncharacterized protein. (192 aa)
	ENSCSEP00000012655	DNA_pol_D_N domain-containing protein. (396 aa)
	LOC103391970	Uncharacterized protein. (706 aa)
	ENSCSEP00000014350	Uncharacterized protein. (206 aa)
	ENSCSEP00000014952	B30.2/SPRY domain-containing protein. (201 aa)
	ENSCSEP00000016388	Ubiquitin specific peptidase 31; Belongs to the peptidase C19 family. (1241 aa)
	pold2	Polymerase (DNA directed), delta 2, regulatory subunit. (519 aa)
	ENSCSEP00000016996	Uncharacterized protein. (238 aa)
	ENSCSEP00000017733	RING-type domain-containing protein. (249 aa)
	LOC103395196	FinTRIM family, member 82. (574 aa)
	LOC103389945	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
	LOC103384111	Uncharacterized protein. (575 aa)
	rfc3	Replication factor C (activator 1) 3. (356 aa)
	LOC103395242	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (633 aa)
	ENSCSEP00000020096	Uncharacterized protein. (707 aa)
	LOC103396403	FinTRIM family, member 67. (432 aa)
	ENSCSEP00000020203	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (315 aa)
	ENSCSEP00000020293	Uncharacterized protein. (564 aa)
	rpa1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
	ENSCSEP00000021183	RING-type domain-containing protein. (229 aa)
	pold1	DNA polymerase. (1077 aa)
	LOC103389779	Tripartite motif containing 25, like. (585 aa)
	ENSCSEP00000023759	Ubiquitin-like domain-containing protein. (92 aa)
	pold4	Si:dkey-28b4.7. (109 aa)
	UBB	Ubiquitin B. (744 aa)
	ENSCSEP00000025195	Uncharacterized protein. (554 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (151 aa)
	ENSCSEP00000025713	RING-type domain-containing protein. (88 aa)
	LOC103384865	Bloodthirsty-related gene family, member 12. (576 aa)
	LOC103384879	Si:dkey-46i9.6. (699 aa)
	ENSCSEP00000027098	B30.2/SPRY domain-containing protein. (666 aa)
	POLE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1996 aa)
	LOC103384513	Uncharacterized protein. (567 aa)
	LOC103384925	Uncharacterized protein. (540 aa)
	ENSCSEP00000028126	RING-type domain-containing protein. (98 aa)
	ENSCSEP00000028128	RING-type domain-containing protein. (72 aa)
	poli	Polymerase (DNA directed) iota. (726 aa)
	rpa2	Replication protein A2. (274 aa)
	rfc2	Replication factor C (activator 1) 2. (355 aa)
	LOC103381995	USP domain-containing protein; Belongs to the peptidase C19 family. (1255 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	pole4	Polymerase (DNA-directed), epsilon 4, accessory subunit. (130 aa)
	LOC103397632	SCY domain-containing protein. (159 aa)
	rfc5	Replication factor C (activator 1) 5. (338 aa)
	LOC103396593	B30.2/SPRY domain-containing protein. (1345 aa)
	ENSCSEP00000033650	Uncharacterized protein. (207 aa)
	pold3	Polymerase (DNA-directed), delta 3, accessory subunit. (419 aa)
	pclaf	PCNA clamp associated factor. (116 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCSEP00000009964	ENSCSEP00000011696	ENSCSEP00000009964	ENSCSEP00000011696	Uncharacterized protein.	Uncharacterized protein.	0.734
ENSCSEP00000009964	ENSCSEP00000012655	ENSCSEP00000009964	ENSCSEP00000012655	Uncharacterized protein.	DNA_pol_D_N domain-containing protein.	0.626
ENSCSEP00000009964	ENSCSEP00000020096	ENSCSEP00000009964	ENSCSEP00000020096	Uncharacterized protein.	Uncharacterized protein.	0.647
ENSCSEP00000009964	ENSCSEP00000020203	ENSCSEP00000009964	ENSCSEP00000020203	Uncharacterized protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.720
ENSCSEP00000009964	LOC103389945	ENSCSEP00000009964	ENSCSEP00000018272	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.529
ENSCSEP00000009964	LOC103395242	ENSCSEP00000009964	ENSCSEP00000019947	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.973
ENSCSEP00000009964	LOC103397632	ENSCSEP00000009964	ENSCSEP00000031535	Uncharacterized protein.	SCY domain-containing protein.	0.672
ENSCSEP00000009964	POLE	ENSCSEP00000009964	ENSCSEP00000027709	Uncharacterized protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.720
ENSCSEP00000009964	Pold2	ENSCSEP00000009964	ENSCSEP00000010635	Uncharacterized protein.	Uncharacterized protein.	0.626
ENSCSEP00000009964	Polh	ENSCSEP00000009964	ENSCSEP00000001349	Uncharacterized protein.	Polymerase (DNA directed), eta.	0.650
ENSCSEP00000009964	Polk	ENSCSEP00000009964	ENSCSEP00000018474	Uncharacterized protein.	Polymerase (DNA directed) kappa.	0.618
ENSCSEP00000009964	UBB	ENSCSEP00000009964	ENSCSEP00000025180	Uncharacterized protein.	Ubiquitin B.	0.653
ENSCSEP00000009964	meiob	ENSCSEP00000009964	ENSCSEP00000001347	Uncharacterized protein.	Methionine sulfoxide reductase B1b.	0.962
ENSCSEP00000009964	pclaf	ENSCSEP00000009964	ENSCSEP00000033965	Uncharacterized protein.	PCNA clamp associated factor.	0.647
ENSCSEP00000009964	pcna	ENSCSEP00000009964	ENSCSEP00000030429	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.728
ENSCSEP00000009964	pold1	ENSCSEP00000009964	ENSCSEP00000021597	Uncharacterized protein.	DNA polymerase.	0.793
ENSCSEP00000009964	pold2	ENSCSEP00000009964	ENSCSEP00000016634	Uncharacterized protein.	Polymerase (DNA directed), delta 2, regulatory subunit.	0.626
ENSCSEP00000009964	pole2	ENSCSEP00000009964	ENSCSEP00000007344	Uncharacterized protein.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.722
ENSCSEP00000009964	pole3	ENSCSEP00000009964	ENSCSEP00000009339	Uncharacterized protein.	Polymerase (DNA directed), epsilon 3 (p17 subunit).	0.689
ENSCSEP00000009964	pole4	ENSCSEP00000009964	ENSCSEP00000031533	Uncharacterized protein.	Polymerase (DNA-directed), epsilon 4, accessory subunit.	0.723