59 items (Cynoglossus semilaevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sumo2	Ubiquitin-like domain-containing protein. (149 aa)
	LOC103395242	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (633 aa)
	xpa	Xeroderma pigmentosum, complementation group A. (270 aa)
	LOC103379116	Protein inhibitor of activated STAT, 1a. (723 aa)
	rpa1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
	LOC103393630	Ubiquitin-like domain-containing protein. (179 aa)
	gtf2h3	General transcription factor IIH, polypeptide 3. (327 aa)
	ENSCSEP00000023759	Ubiquitin-like domain-containing protein. (92 aa)
	LOC103397561	General transcription factor IIH subunit. (414 aa)
	UBB	Ubiquitin B. (744 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (151 aa)
	cdk7	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (344 aa)
	ercc3	Excision repair cross-complementation group 3. (785 aa)
	LOC103389086	UBIQUITIN_CONJUGAT_2 domain-containing protein. (144 aa)
	LOC103398851	Potassium channel tetramerization domain containing 2. (237 aa)
	RAD23B	RAD23 homolog B, nucleotide excision repair protein. (382 aa)
	gtf2h4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (461 aa)
	rpa2	Replication protein A2. (274 aa)
	ercc4	Excision repair cross-complementation group 4. (899 aa)
	parp1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa)
	parp2	Poly [ADP-ribose] polymerase. (653 aa)
	LOC103385609	Ubiquitin-conjugating enzyme E2 variant 1. (147 aa)
	LOC103378632	Cullin 4A; Belongs to the cullin family. (759 aa)
	meiob	Methionine sulfoxide reductase B1b. (436 aa)
	mnat1	MNAT1 component of CDK activating kinase. (311 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	rnf111	Ring finger protein 111. (1040 aa)
	LOC103399826	RAD23 homolog A, nucleotide excision repair protein b. (386 aa)
	Cul4b	Cullin 4B; Belongs to the cullin family. (825 aa)
	Parp3	Poly [ADP-ribose] polymerase. (514 aa)
	LOC103383557	Small ubiquitin-related modifier. (96 aa)
	LOC103378402	Small ubiquitin-related modifier. (94 aa)
	Bivm	Basic, immunoglobulin-like variable motif containing. (389 aa)
	LOC103390697	Centrin 4. (217 aa)
	ENSCSEP00000024413	Von Willebrand factor A domain containing 5B2. (1111 aa)
	ENSCSEP00000011008	Helicase ATP-binding domain-containing protein. (357 aa)
	pias1	Protein inhibitor of activated STAT, 1b. (662 aa)
	ddb2	Damage-specific DNA binding protein 2. (499 aa)
	ENSCSEP00000011692	Ubiquitin-like domain-containing protein. (102 aa)
	usp45	Ubiquitin carboxyl-terminal hydrolase. (814 aa)
	LOC103382819	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
	ercc1	Excision repair cross-complementation group 1. (359 aa)
	ube2v2	Ubiquitin-conjugating enzyme E2 variant 2. (158 aa)
	ENSCSEP00000016477	Rad60-SLD domain-containing protein. (141 aa)
	LOC103392195	Small ubiquitin-related modifier. (100 aa)
	Wdr76	WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (546 aa)
	ube2i	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	ddb1	Damage-specific DNA binding protein 1. (1137 aa)
	sumo1	Small ubiquitin-related modifier. (101 aa)
	LOC103380153	Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
	ercc2	Excision repair cross-complementation group 2. (760 aa)
	xpc	Xeroderma pigmentosum, complementation group C. (924 aa)
	kxd1	KxDL motif containing 1. (180 aa)
	ercc5	Excision repair cross-complementation group 5. (1166 aa)
	LOC103393291	Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	ENSCSEP00000009964	Uncharacterized protein. (85 aa)
	gtf2h1	General transcription factor IIH, polypeptide 1. (551 aa)
	rbx1	Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
	cetn3	Uncharacterized protein. (170 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bivm	Cul4b	ENSCSEP00000005308	ENSCSEP00000003233	Basic, immunoglobulin-like variable motif containing.	Cullin 4B; Belongs to the cullin family.	0.587
Bivm	ENSCSEP00000009964	ENSCSEP00000005308	ENSCSEP00000009964	Basic, immunoglobulin-like variable motif containing.	Uncharacterized protein.	0.640
Bivm	ENSCSEP00000011008	ENSCSEP00000005308	ENSCSEP00000011008	Basic, immunoglobulin-like variable motif containing.	Helicase ATP-binding domain-containing protein.	0.696
Bivm	ENSCSEP00000011692	ENSCSEP00000005308	ENSCSEP00000011692	Basic, immunoglobulin-like variable motif containing.	Ubiquitin-like domain-containing protein.	0.478
Bivm	ENSCSEP00000016477	ENSCSEP00000005308	ENSCSEP00000016477	Basic, immunoglobulin-like variable motif containing.	Rad60-SLD domain-containing protein.	0.464
Bivm	ENSCSEP00000024413	ENSCSEP00000005308	ENSCSEP00000024413	Basic, immunoglobulin-like variable motif containing.	Von Willebrand factor A domain containing 5B2.	0.491
Bivm	LOC103378402	ENSCSEP00000005308	ENSCSEP00000004643	Basic, immunoglobulin-like variable motif containing.	Small ubiquitin-related modifier.	0.478
Bivm	LOC103378632	ENSCSEP00000005308	ENSCSEP00000000797	Basic, immunoglobulin-like variable motif containing.	Cullin 4A; Belongs to the cullin family.	0.587
Bivm	LOC103380153	ENSCSEP00000005308	ENSCSEP00000009133	Basic, immunoglobulin-like variable motif containing.	Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.	0.504
Bivm	LOC103382819	ENSCSEP00000005308	ENSCSEP00000015663	Basic, immunoglobulin-like variable motif containing.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.504
Bivm	LOC103383557	ENSCSEP00000005308	ENSCSEP00000004585	Basic, immunoglobulin-like variable motif containing.	Small ubiquitin-related modifier.	0.478
Bivm	LOC103385609	ENSCSEP00000005308	ENSCSEP00000033572	Basic, immunoglobulin-like variable motif containing.	Ubiquitin-conjugating enzyme E2 variant 1.	0.455
Bivm	LOC103389086	ENSCSEP00000005308	ENSCSEP00000026278	Basic, immunoglobulin-like variable motif containing.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.455
Bivm	LOC103390697	ENSCSEP00000005308	ENSCSEP00000006977	Basic, immunoglobulin-like variable motif containing.	Centrin 4.	0.540
Bivm	LOC103392195	ENSCSEP00000005308	ENSCSEP00000017973	Basic, immunoglobulin-like variable motif containing.	Small ubiquitin-related modifier.	0.478
Bivm	LOC103393630	ENSCSEP00000005308	ENSCSEP00000022083	Basic, immunoglobulin-like variable motif containing.	Ubiquitin-like domain-containing protein.	0.587
Bivm	LOC103395242	ENSCSEP00000005308	ENSCSEP00000019947	Basic, immunoglobulin-like variable motif containing.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.684
Bivm	LOC103397561	ENSCSEP00000005308	ENSCSEP00000024966	Basic, immunoglobulin-like variable motif containing.	General transcription factor IIH subunit.	0.892
Bivm	LOC103399826	ENSCSEP00000005308	ENSCSEP00000002970	Basic, immunoglobulin-like variable motif containing.	RAD23 homolog A, nucleotide excision repair protein b.	0.640
Bivm	Parp3	ENSCSEP00000005308	ENSCSEP00000004002	Basic, immunoglobulin-like variable motif containing.	Poly [ADP-ribose] polymerase.	0.496