STRINGSTRING
LOC103390697 LOC103390697 pole2 pole2 RCBTB1 RCBTB1 rfc1 rfc1 ENSCSEP00000008320 ENSCSEP00000008320 actr8 actr8 sumo1 sumo1 LOC103380153 LOC103380153 pole3 pole3 ercc2 ercc2 xpc xpc kxd1 kxd1 ercc5 ercc5 LOC103393291 LOC103393291 ENSCSEP00000009964 ENSCSEP00000009964 gtf2h1 gtf2h1 rbx1 rbx1 Pold2 Pold2 cetn3 cetn3 rcbtb2 rcbtb2 ENSCSEP00000011008 ENSCSEP00000011008 pias1 pias1 ddb2 ddb2 ENSCSEP00000011692 ENSCSEP00000011692 ENSCSEP00000011696 ENSCSEP00000011696 LOC103395242 LOC103395242 sumo2 sumo2 ddb1 ddb1 rfc3 rfc3 ube2i ube2i Wdr76 Wdr76 Polk Polk LOC103392195 LOC103392195 cops4 cops4 pold2 pold2 ENSCSEP00000016477 ENSCSEP00000016477 ube2v2 ube2v2 ercc1 ercc1 LOC103382819 LOC103382819 ENSCSEP00000015249 ENSCSEP00000015249 nfrkb nfrkb usp45 usp45 ino80c ino80c ENSCSEP00000012655 ENSCSEP00000012655 ENSCSEP00000024490 ENSCSEP00000024490 rpap3 rpap3 ENSCSEP00000024413 ENSCSEP00000024413 ENSCSEP00000023855 ENSCSEP00000023855 cops5 cops5 LOC103393630 LOC103393630 pold1 pold1 rpa1 rpa1 LOC103379116 LOC103379116 ENSCSEP00000020203 ENSCSEP00000020203 xpa xpa ENSCSEP00000020096 ENSCSEP00000020096 cops2 cops2 pold3 pold3 LOC103385609 LOC103385609 parp2 parp2 rfc5 rfc5 parp1 parp1 gps1 gps1 cops3 cops3 LOC103397632 LOC103397632 pole4 pole4 cops7a cops7a actr5 actr5 ino80e ino80e ercc4 ercc4 pcna pcna ino80 ino80 LOC103399026 LOC103399026 actb actb rfc2 rfc2 rpa2 rpa2 gtf2h4 gtf2h4 POLE POLE RAD23B RAD23B LOC103398851 LOC103398851 LOC103389086 LOC103389086 ercc3 ercc3 cdk7 cdk7 uba52 uba52 UBB UBB LOC103397561 LOC103397561 pold4 pold4 rfc4 rfc4 LOC103378632 LOC103378632 meiob meiob mnat1 mnat1 rps27a rps27a LOC103376874 LOC103376874 rnf111 rnf111 LOC103399826 LOC103399826 YY1 YY1 Cul4b Cul4b LOC103383494 LOC103383494 Parp3 Parp3 LOC103383536 LOC103383536 LOC103383557 LOC103383557 LOC103378402 LOC103378402 ino80d ino80d ruvbl1 ruvbl1 COPS6 COPS6 Bivm Bivm tfpt tfpt ino80b ino80b mcrs1 mcrs1 ENSCSEP00000023759 ENSCSEP00000023759 gtf2h3 gtf2h3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103390697Centrin 4. (217 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
RCBTB1Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (637 aa)
rfc1Replication factor C subunit 1. (1083 aa)
ENSCSEP00000008320Si:ch73-290k24.6. (224 aa)
actr8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (638 aa)
sumo1Small ubiquitin-related modifier. (101 aa)
LOC103380153Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (149 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
xpcXeroderma pigmentosum, complementation group C. (924 aa)
kxd1KxDL motif containing 1. (180 aa)
ercc5Excision repair cross-complementation group 5. (1166 aa)
LOC103393291Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
ENSCSEP00000009964Uncharacterized protein. (85 aa)
gtf2h1General transcription factor IIH, polypeptide 1. (551 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
Pold2Uncharacterized protein. (78 aa)
cetn3Uncharacterized protein. (170 aa)
rcbtb2Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (554 aa)
ENSCSEP00000011008Helicase ATP-binding domain-containing protein. (357 aa)
pias1Protein inhibitor of activated STAT, 1b. (662 aa)
ddb2Damage-specific DNA binding protein 2. (499 aa)
ENSCSEP00000011692Ubiquitin-like domain-containing protein. (102 aa)
ENSCSEP00000011696Uncharacterized protein. (103 aa)
LOC103395242Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (633 aa)
sumo2Ubiquitin-like domain-containing protein. (149 aa)
ddb1Damage-specific DNA binding protein 1. (1137 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
ube2iUbiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
Wdr76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (546 aa)
PolkPolymerase (DNA directed) kappa. (867 aa)
LOC103392195Small ubiquitin-related modifier. (100 aa)
cops4COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis). (489 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (519 aa)
ENSCSEP00000016477Rad60-SLD domain-containing protein. (141 aa)
ube2v2Ubiquitin-conjugating enzyme E2 variant 2. (158 aa)
ercc1Excision repair cross-complementation group 1. (359 aa)
LOC103382819UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
ENSCSEP00000015249Uncharacterized protein. (146 aa)
nfrkbNuclear factor related to kappaB binding protein. (1221 aa)
usp45Ubiquitin carboxyl-terminal hydrolase. (814 aa)
ino80cINO80 complex subunit C. (201 aa)
ENSCSEP00000012655DNA_pol_D_N domain-containing protein. (396 aa)
ENSCSEP00000024490TPR_REGION domain-containing protein. (128 aa)
rpap3RNA polymerase II associated protein 3. (650 aa)
ENSCSEP00000024413Von Willebrand factor A domain containing 5B2. (1111 aa)
ENSCSEP00000023855COP9 signalosome subunit 8. (191 aa)
cops5COP9 signalosome subunit 5. (339 aa)
LOC103393630Ubiquitin-like domain-containing protein. (179 aa)
pold1DNA polymerase. (1077 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
LOC103379116Protein inhibitor of activated STAT, 1a. (723 aa)
ENSCSEP00000020203DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (315 aa)
xpaXeroderma pigmentosum, complementation group A. (270 aa)
ENSCSEP00000020096Uncharacterized protein. (707 aa)
cops2COP9 signalosome subunit 2. (452 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (419 aa)
LOC103385609Ubiquitin-conjugating enzyme E2 variant 1. (147 aa)
parp2Poly [ADP-ribose] polymerase. (653 aa)
rfc5Replication factor C (activator 1) 5. (338 aa)
parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa)
gps1G protein pathway suppressor 1. (483 aa)
cops3COP9 signalosome subunit 3. (423 aa)
LOC103397632SCY domain-containing protein. (159 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (130 aa)
cops7aCOP9 constitutive photomorphogenic homolog subunit 7A. (268 aa)
actr5Actin related protein 5; Belongs to the actin family. (635 aa)
ino80eINO80 complex subunit E. (231 aa)
ercc4Excision repair cross-complementation group 4. (899 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
ino80INO80 complex ATPase subunit. (1453 aa)
LOC103399026Uncharacterized protein. (52 aa)
actbPutative beta-actin. (375 aa)
rfc2Replication factor C (activator 1) 2. (355 aa)
rpa2Replication protein A2. (274 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (461 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1996 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (382 aa)
LOC103398851Potassium channel tetramerization domain containing 2. (237 aa)
LOC103389086UBIQUITIN_CONJUGAT_2 domain-containing protein. (144 aa)
ercc3Excision repair cross-complementation group 3. (785 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (344 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (151 aa)
UBBUbiquitin B. (744 aa)
LOC103397561General transcription factor IIH subunit. (414 aa)
pold4Si:dkey-28b4.7. (109 aa)
rfc4Replication factor C (activator 1) 4. (358 aa)
LOC103378632Cullin 4A; Belongs to the cullin family. (759 aa)
meiobMethionine sulfoxide reductase B1b. (436 aa)
mnat1MNAT1 component of CDK activating kinase. (311 aa)
rps27aRibosomal protein S27a. (156 aa)
LOC103376874Uncharacterized protein. (350 aa)
rnf111Ring finger protein 111. (1040 aa)
LOC103399826RAD23 homolog A, nucleotide excision repair protein b. (386 aa)
YY1YY1 transcription factor b. (361 aa)
Cul4bCullin 4B; Belongs to the cullin family. (825 aa)
LOC103383494Uncharacterized protein. (375 aa)
Parp3Poly [ADP-ribose] polymerase. (514 aa)
LOC103383536Uncharacterized protein. (539 aa)
LOC103383557Small ubiquitin-related modifier. (96 aa)
LOC103378402Small ubiquitin-related modifier. (94 aa)
ino80dINO80 complex subunit Da. (974 aa)
ruvbl1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
COPS6COP9 signalosome subunit 6. (323 aa)
BivmBasic, immunoglobulin-like variable motif containing. (389 aa)
tfptTCF3 (E2A) fusion partner. (199 aa)
ino80bINO80 complex subunit B. (337 aa)
mcrs1Microspherule protein 1. (479 aa)
ENSCSEP00000023759Ubiquitin-like domain-containing protein. (92 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (327 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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