50 items (Cynoglossus semilaevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSCSEP00000011696	Uncharacterized protein. (103 aa)
	ddb2	Damage-specific DNA binding protein 2. (499 aa)
	ENSCSEP00000011008	Helicase ATP-binding domain-containing protein. (357 aa)
	rcbtb2	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (554 aa)
	Pold2	Uncharacterized protein. (78 aa)
	rbx1	Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
	gtf2h1	General transcription factor IIH, polypeptide 1. (551 aa)
	ENSCSEP00000009964	Uncharacterized protein. (85 aa)
	ercc5	Excision repair cross-complementation group 5. (1166 aa)
	kxd1	KxDL motif containing 1. (180 aa)
	ercc2	Excision repair cross-complementation group 2. (760 aa)
	pole3	Polymerase (DNA directed), epsilon 3 (p17 subunit). (149 aa)
	rfc1	Replication factor C subunit 1. (1083 aa)
	RCBTB1	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (637 aa)
	pole2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
	Parp3	Poly [ADP-ribose] polymerase. (514 aa)
	Cul4b	Cullin 4B; Belongs to the cullin family. (825 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	LOC103378632	Cullin 4A; Belongs to the cullin family. (759 aa)
	rfc4	Replication factor C (activator 1) 4. (358 aa)
	Bivm	Basic, immunoglobulin-like variable motif containing. (389 aa)
	pold3	Polymerase (DNA-directed), delta 3, accessory subunit. (419 aa)
	parp2	Poly [ADP-ribose] polymerase. (653 aa)
	rfc5	Replication factor C (activator 1) 5. (338 aa)
	parp1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa)
	pole4	Polymerase (DNA-directed), epsilon 4, accessory subunit. (130 aa)
	ercc4	Excision repair cross-complementation group 4. (899 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	rfc2	Replication factor C (activator 1) 2. (355 aa)
	rpa2	Replication protein A2. (274 aa)
	gtf2h4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (461 aa)
	POLE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1996 aa)
	ercc3	Excision repair cross-complementation group 3. (785 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (151 aa)
	UBB	Ubiquitin B. (744 aa)
	LOC103397561	General transcription factor IIH subunit. (414 aa)
	pold4	Si:dkey-28b4.7. (109 aa)
	ENSCSEP00000023759	Ubiquitin-like domain-containing protein. (92 aa)
	gtf2h3	General transcription factor IIH, polypeptide 3. (327 aa)
	pold1	DNA polymerase. (1077 aa)
	rpa1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
	ENSCSEP00000020203	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (315 aa)
	xpa	Xeroderma pigmentosum, complementation group A. (270 aa)
	LOC103395242	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (633 aa)
	ddb1	Damage-specific DNA binding protein 1. (1137 aa)
	rfc3	Replication factor C (activator 1) 3. (356 aa)
	Polk	Polymerase (DNA directed) kappa. (867 aa)
	pold2	Polymerase (DNA directed), delta 2, regulatory subunit. (519 aa)
	ercc1	Excision repair cross-complementation group 1. (359 aa)
	ENSCSEP00000012655	DNA_pol_D_N domain-containing protein. (396 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bivm	Cul4b	ENSCSEP00000005308	ENSCSEP00000003233	Basic, immunoglobulin-like variable motif containing.	Cullin 4B; Belongs to the cullin family.	0.587
Bivm	ENSCSEP00000009964	ENSCSEP00000005308	ENSCSEP00000009964	Basic, immunoglobulin-like variable motif containing.	Uncharacterized protein.	0.640
Bivm	ENSCSEP00000011008	ENSCSEP00000005308	ENSCSEP00000011008	Basic, immunoglobulin-like variable motif containing.	Helicase ATP-binding domain-containing protein.	0.696
Bivm	ENSCSEP00000011696	ENSCSEP00000005308	ENSCSEP00000011696	Basic, immunoglobulin-like variable motif containing.	Uncharacterized protein.	0.508
Bivm	ENSCSEP00000012655	ENSCSEP00000005308	ENSCSEP00000012655	Basic, immunoglobulin-like variable motif containing.	DNA_pol_D_N domain-containing protein.	0.659
Bivm	ENSCSEP00000020203	ENSCSEP00000005308	ENSCSEP00000020203	Basic, immunoglobulin-like variable motif containing.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.645
Bivm	LOC103378632	ENSCSEP00000005308	ENSCSEP00000000797	Basic, immunoglobulin-like variable motif containing.	Cullin 4A; Belongs to the cullin family.	0.587
Bivm	LOC103395242	ENSCSEP00000005308	ENSCSEP00000019947	Basic, immunoglobulin-like variable motif containing.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.684
Bivm	LOC103397561	ENSCSEP00000005308	ENSCSEP00000024966	Basic, immunoglobulin-like variable motif containing.	General transcription factor IIH subunit.	0.892
Bivm	POLE	ENSCSEP00000005308	ENSCSEP00000027709	Basic, immunoglobulin-like variable motif containing.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.645
Bivm	Parp3	ENSCSEP00000005308	ENSCSEP00000004002	Basic, immunoglobulin-like variable motif containing.	Poly [ADP-ribose] polymerase.	0.496
Bivm	Pold2	ENSCSEP00000005308	ENSCSEP00000010635	Basic, immunoglobulin-like variable motif containing.	Uncharacterized protein.	0.659
Bivm	Polk	ENSCSEP00000005308	ENSCSEP00000018474	Basic, immunoglobulin-like variable motif containing.	Polymerase (DNA directed) kappa.	0.560
Bivm	UBB	ENSCSEP00000005308	ENSCSEP00000025180	Basic, immunoglobulin-like variable motif containing.	Ubiquitin B.	0.587
Bivm	ddb1	ENSCSEP00000005308	ENSCSEP00000019584	Basic, immunoglobulin-like variable motif containing.	Damage-specific DNA binding protein 1.	0.760
Bivm	ddb2	ENSCSEP00000005308	ENSCSEP00000011378	Basic, immunoglobulin-like variable motif containing.	Damage-specific DNA binding protein 2.	0.698
Bivm	ercc1	ENSCSEP00000005308	ENSCSEP00000015922	Basic, immunoglobulin-like variable motif containing.	Excision repair cross-complementation group 1.	0.857
Bivm	ercc2	ENSCSEP00000005308	ENSCSEP00000009411	Basic, immunoglobulin-like variable motif containing.	Excision repair cross-complementation group 2.	0.946
Bivm	ercc3	ENSCSEP00000005308	ENSCSEP00000025795	Basic, immunoglobulin-like variable motif containing.	Excision repair cross-complementation group 3.	0.960
Bivm	ercc4	ENSCSEP00000005308	ENSCSEP00000030704	Basic, immunoglobulin-like variable motif containing.	Excision repair cross-complementation group 4.	0.879