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LOC103397632 LOC103397632 pold3 pold3 ENSCSEP00000033782 ENSCSEP00000033782 rfc5 rfc5 gps1 gps1 EP300 EP300 uvssa uvssa LOC103386836 LOC103386836 polr2j polr2j cops3 cops3 pole4 pole4 cops7a cops7a ercc4 ercc4 pcna pcna rfc2 rfc2 rpa2 rpa2 gtf2h4 gtf2h4 usp7 usp7 POLE POLE polr2k polr2k ercc8 ercc8 ercc3 ercc3 cdk7 cdk7 uba52 uba52 UBB UBB tceanc2 tceanc2 LOC103397561 LOC103397561 pold4 pold4 polr2h polr2h ENSCSEP00000023855 ENSCSEP00000023855 ENSCSEP00000023759 ENSCSEP00000023759 gtf2h3 gtf2h3 lig3 lig3 ppp1r42 ppp1r42 cops5 cops5 pold1 pold1 tcea1 tcea1 rpa1 rpa1 LOC103394810 LOC103394810 ENSCSEP00000020203 ENSCSEP00000020203 xpa xpa ENSCSEP00000020096 ENSCSEP00000020096 cops2 cops2 LOC103395242 LOC103395242 ddb1 ddb1 rfc3 rfc3 ENSCSEP00000019257 ENSCSEP00000019257 polr2g polr2g xab2 xab2 Polk Polk cops4 cops4 ZNF830 ZNF830 pold2 pold2 prpf19 prpf19 ercc1 ercc1 LOC103385145 LOC103385145 ENSCSEP00000012655 ENSCSEP00000012655 ENSCSEP00000011696 ENSCSEP00000011696 ercc6 ercc6 POLR2E POLR2E rcbtb2 rcbtb2 polr2f polr2f Pold2 Pold2 rbx1 rbx1 ENSCSEP00000010137 ENSCSEP00000010137 gtf2h1 gtf2h1 ENSCSEP00000009964 ENSCSEP00000009964 ercc5 ercc5 polr2d polr2d kxd1 kxd1 ercc2 ercc2 pole3 pole3 polr2b polr2b tcea3 tcea3 TCEANC TCEANC phf3 phf3 rfc1 rfc1 RCBTB1 RCBTB1 aqr aqr pole2 pole2 Bivm Bivm COPS6 COPS6 usp40 usp40 polr2a polr2a polr2i polr2i Cul4b Cul4b polr2l polr2l polr2c polr2c rps27a rps27a mnat1 mnat1 meiob meiob LOC103378632 LOC103378632 rfc4 rfc4 nrde2 nrde2 ppie ppie
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103397632SCY domain-containing protein. (159 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (419 aa)
ENSCSEP00000033782DNA ligase. (633 aa)
rfc5Replication factor C (activator 1) 5. (338 aa)
gps1G protein pathway suppressor 1. (483 aa)
EP300E1A binding protein p300. (2880 aa)
uvssaUV-stimulated scaffold protein A. (760 aa)
LOC103386836ISY1 splicing factor homolog. (323 aa)
polr2jPolymerase (RNA) II (DNA directed) polypeptide J. (117 aa)
cops3COP9 signalosome subunit 3. (423 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (130 aa)
cops7aCOP9 constitutive photomorphogenic homolog subunit 7A. (268 aa)
ercc4Excision repair cross-complementation group 4. (899 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
rfc2Replication factor C (activator 1) 2. (355 aa)
rpa2Replication protein A2. (274 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (461 aa)
usp7Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1117 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1996 aa)
polr2kPolymerase (RNA) II (DNA directed) polypeptide K. (58 aa)
ercc8Excision repair cross-complementation group 8. (429 aa)
ercc3Excision repair cross-complementation group 3. (785 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (344 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (151 aa)
UBBUbiquitin B. (744 aa)
tceanc2TFIIS N-terminal domain-containing protein. (298 aa)
LOC103397561General transcription factor IIH subunit. (414 aa)
pold4Si:dkey-28b4.7. (109 aa)
polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (155 aa)
ENSCSEP00000023855COP9 signalosome subunit 8. (191 aa)
ENSCSEP00000023759Ubiquitin-like domain-containing protein. (92 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (327 aa)
lig3DNA ligase. (1015 aa)
ppp1r42Protein phosphatase 1, regulatory subunit 42. (309 aa)
cops5COP9 signalosome subunit 5. (339 aa)
pold1DNA polymerase. (1077 aa)
tcea1Transcription elongation factor A (SII), 1. (327 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
LOC103394810Si:ch73-1a9.3. (82 aa)
ENSCSEP00000020203DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (315 aa)
xpaXeroderma pigmentosum, complementation group A. (270 aa)
ENSCSEP00000020096Uncharacterized protein. (707 aa)
cops2COP9 signalosome subunit 2. (452 aa)
LOC103395242Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (633 aa)
ddb1Damage-specific DNA binding protein 1. (1137 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
ENSCSEP00000019257X-ray repair complementing defective repair in Chinese hamster cells 1. (567 aa)
polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (190 aa)
xab2XPA binding protein 2. (851 aa)
PolkPolymerase (DNA directed) kappa. (867 aa)
cops4COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis). (489 aa)
ZNF830Zinc finger protein 830. (347 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (519 aa)
prpf19Pre-mRNA processing factor 19. (504 aa)
ercc1Excision repair cross-complementation group 1. (359 aa)
LOC103385145Transcription elongation factor A (SII), 2. (297 aa)
ENSCSEP00000012655DNA_pol_D_N domain-containing protein. (396 aa)
ENSCSEP00000011696Uncharacterized protein. (103 aa)
ercc6Excision repair cross-complementation group 6. (1444 aa)
POLR2ERNA polymerase II subunit E. (229 aa)
rcbtb2Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (554 aa)
polr2fPolymerase (RNA) II (DNA directed) polypeptide F. (127 aa)
Pold2Uncharacterized protein. (78 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
ENSCSEP00000010137E1A binding protein p300 b. (2546 aa)
gtf2h1General transcription factor IIH, polypeptide 1. (551 aa)
ENSCSEP00000009964Uncharacterized protein. (85 aa)
ercc5Excision repair cross-complementation group 5. (1166 aa)
polr2dPolymerase (RNA) II (DNA directed) polypeptide D. (144 aa)
kxd1KxDL motif containing 1. (180 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (149 aa)
polr2bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
tcea3Transcription elongation factor A (SII), 3. (606 aa)
TCEANCTranscription elongation factor A N-terminal and central domain containing. (293 aa)
phf3PHD finger protein 3. (1661 aa)
rfc1Replication factor C subunit 1. (1083 aa)
RCBTB1Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (637 aa)
aqrAquarius intron-binding spliceosomal factor. (1377 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
BivmBasic, immunoglobulin-like variable motif containing. (389 aa)
COPS6COP9 signalosome subunit 6. (323 aa)
usp40Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (1230 aa)
polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1965 aa)
polr2iPolymerase (RNA) II (DNA directed) polypeptide I. (287 aa)
Cul4bCullin 4B; Belongs to the cullin family. (825 aa)
polr2lPolymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
polr2cPolymerase (RNA) II (DNA directed) polypeptide C. (275 aa)
rps27aRibosomal protein S27a. (156 aa)
mnat1MNAT1 component of CDK activating kinase. (311 aa)
meiobMethionine sulfoxide reductase B1b. (436 aa)
LOC103378632Cullin 4A; Belongs to the cullin family. (759 aa)
rfc4Replication factor C (activator 1) 4. (358 aa)
nrde2NRDE-2, necessary for RNA interference, domain containing. (1106 aa)
ppiePeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (304 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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