STRINGSTRING
LOC103397632 LOC103397632 polr2j polr2j ppie ppie nrde2 nrde2 rfc4 rfc4 LOC103378632 LOC103378632 meiob meiob mnat1 mnat1 rps27a rps27a polr2c polr2c polr2l polr2l Cul4b Cul4b polr2i polr2i polr2a polr2a pold3 pold3 usp40 usp40 Bivm Bivm pole2 pole2 aqr aqr RCBTB1 RCBTB1 rfc1 rfc1 phf3 phf3 TCEANC TCEANC tcea3 tcea3 polr2b polr2b pole3 pole3 ercc2 ercc2 kxd1 kxd1 polr2d polr2d ercc5 ercc5 ENSCSEP00000009964 ENSCSEP00000009964 gtf2h1 gtf2h1 ENSCSEP00000010137 ENSCSEP00000010137 rbx1 rbx1 Pold2 Pold2 polr2f polr2f rcbtb2 rcbtb2 POLR2E POLR2E ercc6 ercc6 uvssa uvssa ENSCSEP00000011696 ENSCSEP00000011696 ENSCSEP00000012655 ENSCSEP00000012655 LOC103385145 LOC103385145 ercc1 ercc1 prpf19 prpf19 pold2 pold2 ZNF830 ZNF830 Polk Polk xab2 xab2 polr2g polr2g rfc3 rfc3 ddb1 ddb1 LOC103395242 LOC103395242 ENSCSEP00000020096 ENSCSEP00000020096 xpa xpa ENSCSEP00000020203 ENSCSEP00000020203 LOC103394810 LOC103394810 rpa1 rpa1 tcea1 tcea1 pold1 pold1 gtf2h3 gtf2h3 ENSCSEP00000023759 ENSCSEP00000023759 polr2h polr2h pold4 pold4 LOC103397561 LOC103397561 tceanc2 tceanc2 UBB UBB uba52 uba52 cdk7 cdk7 ercc3 ercc3 ercc8 ercc8 polr2k polr2k POLE POLE usp7 usp7 gtf2h4 gtf2h4 rpa2 rpa2 rfc5 rfc5 rfc2 rfc2 pcna pcna ercc4 ercc4 pole4 pole4 LOC103386836 LOC103386836 EP300 EP300
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103397632SCY domain-containing protein. (159 aa)
polr2jPolymerase (RNA) II (DNA directed) polypeptide J. (117 aa)
ppiePeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (304 aa)
nrde2NRDE-2, necessary for RNA interference, domain containing. (1106 aa)
rfc4Replication factor C (activator 1) 4. (358 aa)
LOC103378632Cullin 4A; Belongs to the cullin family. (759 aa)
meiobMethionine sulfoxide reductase B1b. (436 aa)
mnat1MNAT1 component of CDK activating kinase. (311 aa)
rps27aRibosomal protein S27a. (156 aa)
polr2cPolymerase (RNA) II (DNA directed) polypeptide C. (275 aa)
polr2lPolymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
Cul4bCullin 4B; Belongs to the cullin family. (825 aa)
polr2iPolymerase (RNA) II (DNA directed) polypeptide I. (287 aa)
polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1965 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (419 aa)
usp40Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (1230 aa)
BivmBasic, immunoglobulin-like variable motif containing. (389 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
aqrAquarius intron-binding spliceosomal factor. (1377 aa)
RCBTB1Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (637 aa)
rfc1Replication factor C subunit 1. (1083 aa)
phf3PHD finger protein 3. (1661 aa)
TCEANCTranscription elongation factor A N-terminal and central domain containing. (293 aa)
tcea3Transcription elongation factor A (SII), 3. (606 aa)
polr2bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (149 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
kxd1KxDL motif containing 1. (180 aa)
polr2dPolymerase (RNA) II (DNA directed) polypeptide D. (144 aa)
ercc5Excision repair cross-complementation group 5. (1166 aa)
ENSCSEP00000009964Uncharacterized protein. (85 aa)
gtf2h1General transcription factor IIH, polypeptide 1. (551 aa)
ENSCSEP00000010137E1A binding protein p300 b. (2546 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
Pold2Uncharacterized protein. (78 aa)
polr2fPolymerase (RNA) II (DNA directed) polypeptide F. (127 aa)
rcbtb2Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (554 aa)
POLR2ERNA polymerase II subunit E. (229 aa)
ercc6Excision repair cross-complementation group 6. (1444 aa)
uvssaUV-stimulated scaffold protein A. (760 aa)
ENSCSEP00000011696Uncharacterized protein. (103 aa)
ENSCSEP00000012655DNA_pol_D_N domain-containing protein. (396 aa)
LOC103385145Transcription elongation factor A (SII), 2. (297 aa)
ercc1Excision repair cross-complementation group 1. (359 aa)
prpf19Pre-mRNA processing factor 19. (504 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (519 aa)
ZNF830Zinc finger protein 830. (347 aa)
PolkPolymerase (DNA directed) kappa. (867 aa)
xab2XPA binding protein 2. (851 aa)
polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (190 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
ddb1Damage-specific DNA binding protein 1. (1137 aa)
LOC103395242Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (633 aa)
ENSCSEP00000020096Uncharacterized protein. (707 aa)
xpaXeroderma pigmentosum, complementation group A. (270 aa)
ENSCSEP00000020203DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (315 aa)
LOC103394810Si:ch73-1a9.3. (82 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
tcea1Transcription elongation factor A (SII), 1. (327 aa)
pold1DNA polymerase. (1077 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (327 aa)
ENSCSEP00000023759Ubiquitin-like domain-containing protein. (92 aa)
polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (155 aa)
pold4Si:dkey-28b4.7. (109 aa)
LOC103397561General transcription factor IIH subunit. (414 aa)
tceanc2TFIIS N-terminal domain-containing protein. (298 aa)
UBBUbiquitin B. (744 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (151 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (344 aa)
ercc3Excision repair cross-complementation group 3. (785 aa)
ercc8Excision repair cross-complementation group 8. (429 aa)
polr2kPolymerase (RNA) II (DNA directed) polypeptide K. (58 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1996 aa)
usp7Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1117 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (461 aa)
rpa2Replication protein A2. (274 aa)
rfc5Replication factor C (activator 1) 5. (338 aa)
rfc2Replication factor C (activator 1) 2. (355 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
ercc4Excision repair cross-complementation group 4. (899 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (130 aa)
LOC103386836ISY1 splicing factor homolog. (323 aa)
EP300E1A binding protein p300. (2880 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.