41 items (Cynoglossus semilaevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103378498	Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
	txndc11	Thioredoxin domain containing 11. (864 aa)
	ENSCSEP00000029916	Death-domain associated protein. (681 aa)
	ENSCSEP00000029804	Uncharacterized protein. (143 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	usp7	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1117 aa)
	rnf34	Ring finger protein 34a. (380 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (151 aa)
	rffl	Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase. (356 aa)
	UBB	Ubiquitin B. (744 aa)
	LOC112486244	Ubiquitin carboxyl-terminal hydrolase. (400 aa)
	LOC103391208	Serine/threonine-protein phosphatase. (309 aa)
	LOC103391216	Cyclin G1; Belongs to the cyclin family. (299 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)
	ENSCSEP00000023759	Ubiquitin-like domain-containing protein. (92 aa)
	SGK1	Non-specific serine/threonine protein kinase. (619 aa)
	pdpk1	3-phosphoinositide dependent protein kinase 1b. (565 aa)
	rictor	RPTOR independent companion of MTOR, complex 2 a. (1534 aa)
	LOC103383890	V-akt murine thymoma viral oncogene homolog 3b; Belongs to the protein kinase superfamily. (484 aa)
	ppp2cb	Serine/threonine-protein phosphatase. (309 aa)
	phf20	PHD finger protein 20, a. (1016 aa)
	LOC103382796	Uncharacterized protein. (465 aa)
	chek2	Checkpoint kinase 2. (550 aa)
	ENSCSEP00000012549	RICTOR_N domain-containing protein. (204 aa)
	ENSCSEP00000012109	Metallophos domain-containing protein. (79 aa)
	mapkap1	MAPK associated protein 1. (542 aa)
	kxd1	KxDL motif containing 1. (180 aa)
	LOC103377788	Ubiquitin carboxyl-terminal hydrolase. (597 aa)
	mtor	Serine/threonine-protein kinase TOR. (2382 aa)
	mdm4	MDM4 regulator of p53; Belongs to the MDM2/MDM4 family. (495 aa)
	ccna2	Cyclin A2; Belongs to the cyclin family. (447 aa)
	cdk2	Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
	ENSCSEP00000005323	MDM2 proto-oncogene. (416 aa)
	LOC103387066	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (476 aa)
	LOC103377652	Non-specific serine/threonine protein kinase. (547 aa)
	Atm	Non-specific serine/threonine protein kinase. (3052 aa)
	cdk1	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (269 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	LOC103390455	Ring finger protein 34b. (426 aa)
	mlst8	MTOR associated protein, LST8 homolog (S. cerevisiae). (326 aa)
	akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT2	Atm	ENSCSEP00000029676	ENSCSEP00000003106	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.428
AKT2	ENSCSEP00000005323	ENSCSEP00000029676	ENSCSEP00000005323	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	MDM2 proto-oncogene.	0.754
AKT2	ENSCSEP00000012109	ENSCSEP00000029676	ENSCSEP00000012109	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Metallophos domain-containing protein.	0.537
AKT2	ENSCSEP00000012549	ENSCSEP00000029676	ENSCSEP00000012549	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	RICTOR_N domain-containing protein.	0.702
AKT2	ENSCSEP00000029804	ENSCSEP00000029676	ENSCSEP00000029804	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.417
AKT2	LOC103377788	ENSCSEP00000029676	ENSCSEP00000007863	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Ubiquitin carboxyl-terminal hydrolase.	0.401
AKT2	LOC103378498	ENSCSEP00000029676	ENSCSEP00000028334	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Protein phosphatase 2, regulatory subunit A, beta b.	0.576
AKT2	LOC103387066	ENSCSEP00000029676	ENSCSEP00000004739	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.928
AKT2	LOC103391208	ENSCSEP00000029676	ENSCSEP00000024173	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Serine/threonine-protein phosphatase.	0.537
AKT2	LOC112486244	ENSCSEP00000029676	ENSCSEP00000024761	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Ubiquitin carboxyl-terminal hydrolase.	0.401
AKT2	SGK1	ENSCSEP00000029676	ENSCSEP00000022341	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.550
AKT2	akt1	ENSCSEP00000029676	ENSCSEP00000000181	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.901
AKT2	mapkap1	ENSCSEP00000029676	ENSCSEP00000011334	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	MAPK associated protein 1.	0.696
AKT2	mdm4	ENSCSEP00000029676	ENSCSEP00000007236	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	MDM4 regulator of p53; Belongs to the MDM2/MDM4 family.	0.608
AKT2	mlst8	ENSCSEP00000029676	ENSCSEP00000001354	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	MTOR associated protein, LST8 homolog (S. cerevisiae).	0.610
AKT2	mtor	ENSCSEP00000029676	ENSCSEP00000007848	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Serine/threonine-protein kinase TOR.	0.975
AKT2	pdpk1	ENSCSEP00000029676	ENSCSEP00000019033	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	3-phosphoinositide dependent protein kinase 1b.	0.984
AKT2	phf20	ENSCSEP00000029676	ENSCSEP00000014636	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	PHD finger protein 20, a.	0.417
AKT2	ppp2ca	ENSCSEP00000029676	ENSCSEP00000023851	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Serine/threonine-protein phosphatase.	0.537
AKT2	ppp2cb	ENSCSEP00000029676	ENSCSEP00000015299	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Serine/threonine-protein phosphatase.	0.537