79 items (Cynoglossus semilaevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC103386740	Tyrosine-protein kinase. (558 aa)
	eps15	Epidermal growth factor receptor pathway substrate 15. (1099 aa)
	ENSCSEP00000031725	SH3 domain containing 21. (398 aa)
	gab1	GRB2-associated binding protein 1. (835 aa)
	met	MET proto-oncogene, receptor tyrosine kinase. (1420 aa)
	ranbp9	RAN binding protein 9. (624 aa)
	LOC103385603	RAP1A, member of RAS oncogene family a. (185 aa)
	ENSCSEP00000033581	Protein tyrosine phosphatase non-receptor type 1. (326 aa)
	spint1	Serine peptidase inhibitor, Kunitz type 1 a. (510 aa)
	LOC103395101	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (175 aa)
	rab4a	RAB4a, member RAS oncogene family. (213 aa)
	ENSCSEP00000002131	LAM_G_DOMAIN domain-containing protein. (255 aa)
	ENSCSEP00000002136	Fibrillar collagen NC1 domain-containing protein. (111 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	ENSCSEP00000002927	ADP-ribosylation factor 6a. (114 aa)
	shc1	SHC (Src homology 2 domain containing) transforming protein 1. (731 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (917 aa)
	LOC103383561	Uncharacterized protein. (716 aa)
	sh3gl1	SH3-domain GRB2-like 1b. (352 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (1205 aa)
	stam2	Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2. (521 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (305 aa)
	LOC103382506	Uncharacterized protein. (184 aa)
	hgf	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (708 aa)
	LOC103377807	CRK proto-oncogene, adaptor protein. (315 aa)
	lrig1	Leucine-rich repeats and immunoglobulin-like domains 1. (1078 aa)
	LOC103389712	Uncharacterized protein. (353 aa)
	kras	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
	TNS1	Tensin 1. (1043 aa)
	LOC103381353	Uncharacterized protein. (621 aa)
	ENSCSEP00000010018	Fibrillar collagen NC1 domain-containing protein. (112 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1276 aa)
	ENSCSEP00000011448	PI3K-ABD domain-containing protein; Belongs to the PI3/PI4-kinase family. (123 aa)
	LOC103379201	SH3-domain GRB2-like 3a. (384 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	ENSCSEP00000012566	Uncharacterized protein. (130 aa)
	LOC103397946	Uncharacterized protein. (504 aa)
	LOC103378089	RAB4B, member RAS oncogene family. (236 aa)
	ENSCSEP00000013475	Laminin, alpha 5. (3616 aa)
	hgs	Hepatocyte growth factor-regulated tyrosine kinase substrate. (803 aa)
	ENSCSEP00000013843	Uncharacterized protein. (302 aa)
	LOC103383863	SH3 domain containing GRB2 like 2a, endophilin A1. (354 aa)
	TNS3-2	Tensin 3. (1364 aa)
	hpn	Hepsin; Belongs to the peptidase S1 family. (479 aa)
	gga3	Golgi associated, gamma adaptin ear containing, ARF binding protein 3b. (706 aa)
	Shc4	Uncharacterized protein. (342 aa)
	ptpn2	Tyrosine-protein phosphatase non-receptor type. (417 aa)
	LOC103392975	Zgc:55558. (187 aa)
	ranbp10	RAN binding protein 10. (605 aa)
	stam	Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1. (443 aa)
	grb2	Growth factor receptor-bound protein 2b. (220 aa)
	TNS4	Tensin 4. (580 aa)
	lamc1	Laminin, gamma 1. (1470 aa)
	LOC103385228	Tyrosine-protein kinase. (551 aa)
	ENSCSEP00000023261	Uncharacterized protein. (869 aa)
	Lamc3	Laminin N-terminal domain-containing protein. (267 aa)
	ENSCSEP00000023308	Uncharacterized protein. (127 aa)
	cblc	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (550 aa)
	LOC103394276	Tyrosine-protein phosphatase non-receptor type. (395 aa)
	ENSCSEP00000023759	Ubiquitin-like domain-containing protein. (92 aa)
	ENSCSEP00000023995	Rap guanine nucleotide exchange factor (GEF) 1b. (683 aa)
	LOC103395373	Uncharacterized protein. (319 aa)
	ENSCSEP00000025147	SH2 domain-containing protein. (605 aa)
	UBB	Ubiquitin B. (744 aa)
	ENSCSEP00000025193	Uncharacterized protein. (360 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (151 aa)
	cbl	Cbl proto-oncogene, E3 ubiquitin protein ligase. (952 aa)
	LOC103395395	Uncharacterized protein. (869 aa)
	LOC103396148	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
	ENSCSEP00000026654	Laminin, alpha 4. (1776 aa)
	LOC103386619	Uncharacterized protein. (1150 aa)
	ENSCSEP00000028257	Dedicator of cytokinesis 7; Belongs to the DOCK family. (621 aa)
	ENSCSEP00000028324	Uncharacterized protein. (423 aa)
	Lama3	Uncharacterized protein. (568 aa)
	ENSCSEP00000028367	Uncharacterized protein. (117 aa)
	sh3kbp1	SH3-domain kinase binding protein 1. (611 aa)
	ENSCSEP00000029255	DHR-2 domain-containing protein; Belongs to the DOCK family. (303 aa)
	LOC103386699	Uncharacterized protein. (185 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	ENSCSEP00000011448	ENSCSEP00000004032	ENSCSEP00000011448	Cold shock domain containing E1, RNA-binding.	PI3K-ABD domain-containing protein; Belongs to the PI3/PI4-kinase family.	0.525
CSDE1	ENSCSEP00000023759	ENSCSEP00000004032	ENSCSEP00000023759	Cold shock domain containing E1, RNA-binding.	Ubiquitin-like domain-containing protein.	0.454
CSDE1	ENSCSEP00000023995	ENSCSEP00000004032	ENSCSEP00000023995	Cold shock domain containing E1, RNA-binding.	Rap guanine nucleotide exchange factor (GEF) 1b.	0.403
CSDE1	LOC103382506	ENSCSEP00000004032	ENSCSEP00000006488	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein.	0.400
CSDE1	LOC103385603	ENSCSEP00000004032	ENSCSEP00000033583	Cold shock domain containing E1, RNA-binding.	RAP1A, member of RAS oncogene family a.	0.400
CSDE1	LOC103386699	ENSCSEP00000004032	ENSCSEP00000029508	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein.	0.400
CSDE1	LOC103396148	ENSCSEP00000004032	ENSCSEP00000026590	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.525
CSDE1	LOC103397946	ENSCSEP00000004032	ENSCSEP00000012744	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein.	0.403
CSDE1	PIK3CA	ENSCSEP00000004032	ENSCSEP00000030420	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.525
CSDE1	Shc4	ENSCSEP00000004032	ENSCSEP00000020040	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein.	0.432
CSDE1	UBB	ENSCSEP00000004032	ENSCSEP00000025180	Cold shock domain containing E1, RNA-binding.	Ubiquitin B.	0.539
CSDE1	grb2	ENSCSEP00000004032	ENSCSEP00000022549	Cold shock domain containing E1, RNA-binding.	Growth factor receptor-bound protein 2b.	0.680
CSDE1	met	ENSCSEP00000004032	ENSCSEP00000033286	Cold shock domain containing E1, RNA-binding.	MET proto-oncogene, receptor tyrosine kinase.	0.637
CSDE1	rps27a	ENSCSEP00000004032	ENSCSEP00000002392	Cold shock domain containing E1, RNA-binding.	Ribosomal protein S27a.	0.508
CSDE1	shc1	ENSCSEP00000004032	ENSCSEP00000003236	Cold shock domain containing E1, RNA-binding.	SHC (Src homology 2 domain containing) transforming protein 1.	0.432
CSDE1	uba52	ENSCSEP00000004032	ENSCSEP00000025345	Cold shock domain containing E1, RNA-binding.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.454
ENSCSEP00000002131	ENSCSEP00000002136	ENSCSEP00000002131	ENSCSEP00000002136	LAM_G_DOMAIN domain-containing protein.	Fibrillar collagen NC1 domain-containing protein.	0.852
ENSCSEP00000002131	ENSCSEP00000010018	ENSCSEP00000002131	ENSCSEP00000010018	LAM_G_DOMAIN domain-containing protein.	Fibrillar collagen NC1 domain-containing protein.	0.519
ENSCSEP00000002136	ENSCSEP00000002131	ENSCSEP00000002136	ENSCSEP00000002131	Fibrillar collagen NC1 domain-containing protein.	LAM_G_DOMAIN domain-containing protein.	0.852
ENSCSEP00000002927	LOC103377807	ENSCSEP00000002927	ENSCSEP00000008215	ADP-ribosylation factor 6a.	CRK proto-oncogene, adaptor protein.	0.546