STRINGSTRING
ENSCSEP00000022777 ENSCSEP00000022777 LOC103378260 LOC103378260 psmd9 psmd9 LOC103381864 LOC103381864 ENSCSEP00000023759 ENSCSEP00000023759 skp1 skp1 ppp2ca ppp2ca psme2 psme2 psme3 psme3 LOC103391208 LOC103391208 fnbp4 fnbp4 Cdc25b Cdc25b psmc6 psmc6 Mcm9 Mcm9 UBB UBB cul1 cul1 uba52 uba52 psmb3 psmb3 cdk7 cdk7 LOC103382982 LOC103382982 mcm8 mcm8 gmnn gmnn cdc7 cdc7 POLE POLE ENSCSEP00000028052 ENSCSEP00000028052 LOC103389149 LOC103389149 LOC103378498 LOC103378498 ENSCSEP00000028678 ENSCSEP00000028678 psmd10 psmd10 Mcm6 Mcm6 LOC103381415 LOC103381415 kxd1 kxd1 pole3 pole3 psmd13 psmd13 psmb6 psmb6 psmd7 psmd7 psmd6 psmd6 psmd2 psmd2 psmc1 psmc1 LOC103389192 LOC103389192 AKT2 AKT2 psma6 psma6 rpa2 rpa2 psmb8 psmb8 LOC103393839 LOC103393839 LOC103393840 LOC103393840 psmb4 psmb4 cdc45 cdc45 psmc3 psmc3 ppp4r1 ppp4r1 Mcm10 Mcm10 pole4 pole4 LOC103397632 LOC103397632 LOC103386842 LOC103386842 ccne2 ccne2 mcm2 mcm2 prim1 prim1 LOC103396604 LOC103396604 LOC103385602 LOC103385602 PPP2R3B PPP2R3B LOC107989765 LOC107989765 pole2 pole2 pola2 pola2 psma5 psma5 ccna2 ccna2 cdk4 cdk4 cdk2 cdk2 LOC103380040 LOC103380040 Ppp2r3a Ppp2r3a mcm7 mcm7 LOC103387066 LOC103387066 LOC103378807 LOC103378807 LOC103377652 LOC103377652 orc3 orc3 LOC103379956 LOC103379956 rbbp8nl rbbp8nl Ppp2r3c Ppp2r3c akt1 akt1 psmb1 psmb1 LOC103398252 LOC103398252 ccne1 ccne1 psmd14 psmd14 meiob meiob psma1 psma1 wee1 wee1 orc1 orc1 CCND1 CCND1 psmd5 psmd5 LOC103385882 LOC103385882 PSMD4 PSMD4 LOC103379914 LOC103379914 dbf4 dbf4 rps27a rps27a mnat1 mnat1 psme1 psme1 ppp2cb ppp2cb cdc6 cdc6 mcm4 mcm4 ENSCSEP00000016476 ENSCSEP00000016476 LOC103383890 LOC103383890 mcm3 mcm3 psmb2 psmb2 pola1 pola1 psma2 psma2 cables1 cables1 LOC103382906 LOC103382906 LOC103382905 LOC103382905 ENSCSEP00000018052 ENSCSEP00000018052 psma3 psma3 PSMC5 PSMC5 ENSCSEP00000009900 ENSCSEP00000009900 ENSCSEP00000009964 ENSCSEP00000009964 orc4 orc4 Orc5 Orc5 ENSCSEP00000011109 ENSCSEP00000011109 LOC103394542 LOC103394542 LOC103389639 LOC103389639 LOC103394526 LOC103394526 LOC103399400 LOC103399400 ENSCSEP00000012109 ENSCSEP00000012109 psmd3 psmd3 LOC103385141 LOC103385141 kiaa1468 kiaa1468 LOC103385164 LOC103385164 ENSCSEP00000013775 ENSCSEP00000013775 cdkn1b cdkn1b psmc4 psmc4 psmd12 psmd12 LOC103379080 LOC103379080 LOC103398645 LOC103398645 LOC103395242 LOC103395242 LOC103393606 LOC103393606 ENSCSEP00000020203 ENSCSEP00000020203 rpa1 rpa1 psmd1 psmd1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSCSEP00000022777DNA helicase; Belongs to the MCM family. (683 aa)
LOC103378260Proteasome subunit alpha type. (267 aa)
psmd9Proteasome 26S subunit, non-ATPase 9. (212 aa)
LOC103381864Proteasome 26S subunit, non-ATPase 11b. (422 aa)
ENSCSEP00000023759Ubiquitin-like domain-containing protein. (92 aa)
skp1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (193 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
psme2Proteasome activator subunit 2. (245 aa)
psme3Proteasome activator subunit 3. (240 aa)
LOC103391208Serine/threonine-protein phosphatase. (309 aa)
fnbp4Formin binding protein 4. (880 aa)
Cdc25bRhodanese domain-containing protein. (568 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (407 aa)
Mcm9Uncharacterized protein. (131 aa)
UBBUbiquitin B. (744 aa)
cul1Cullin 1b; Belongs to the cullin family. (766 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (151 aa)
psmb3Proteasome subunit beta. (205 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (344 aa)
LOC103382982Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
mcm8Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (859 aa)
gmnnGeminin DNA replication inhibitor. (225 aa)
cdc7Cell division cycle 7 homolog (S. cerevisiae). (582 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1996 aa)
ENSCSEP00000028052Chromatin licensing and DNA replication factor 1. (633 aa)
LOC103389149Proteasome subunit beta. (276 aa)
LOC103378498Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
ENSCSEP00000028678Retinoblastoma 1. (872 aa)
psmd10Proteasome 26S subunit, non-ATPase 10. (209 aa)
Mcm6DNA helicase; Belongs to the MCM family. (688 aa)
LOC103381415Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (398 aa)
kxd1KxDL motif containing 1. (180 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (149 aa)
psmd13Proteasome 26S subunit, non-ATPase 13. (391 aa)
psmb6Proteasome subunit beta. (234 aa)
psmd7Proteasome 26S subunit, non-ATPase 7. (330 aa)
psmd6Proteasome 26S subunit, non-ATPase 6. (389 aa)
psmd226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (833 aa)
psmc1Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (440 aa)
LOC103389192S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (425 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
psma6Proteasome subunit alpha type. (246 aa)
rpa2Replication protein A2. (274 aa)
psmb8Proteasome subunit beta. (271 aa)
LOC103393839Proteasome subunit beta 13a. (281 aa)
LOC103393840Proteasome subunit beta 12. (217 aa)
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (226 aa)
cdc45CDC45 cell division cycle 45 homolog (S. cerevisiae). (568 aa)
psmc3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (404 aa)
ppp4r1WRNPLPNID domain-containing protein. (1060 aa)
Mcm10Zf-primase domain-containing protein. (203 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (130 aa)
LOC103397632SCY domain-containing protein. (159 aa)
LOC103386842Proteasome inhibitor subunit 1. (280 aa)
ccne2Cyclin E2; Belongs to the cyclin family. (399 aa)
mcm2DNA helicase; Belongs to the MCM family. (885 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (396 aa)
LOC103396604Proteasome subunit beta. (278 aa)
LOC103385602Cdk5 and Abl enzyme substrate 2a; Belongs to the cyclin family. (354 aa)
PPP2R3BEF-hand domain-containing protein. (579 aa)
LOC107989765Uncharacterized protein. (800 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (601 aa)
psma5Proteasome subunit alpha type. (241 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (447 aa)
cdk4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (305 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
LOC103380040Wee1-like protein kinase. (546 aa)
Ppp2r3aProtein phosphatase 2, regulatory subunit B'', alpha. (1106 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa)
LOC103387066Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (476 aa)
LOC103378807Uncharacterized protein. (176 aa)
LOC103377652Non-specific serine/threonine protein kinase. (547 aa)
orc3Origin recognition complex, subunit 3. (719 aa)
LOC103379956Cyclin-dependent kinase inhibitor 1Cb. (273 aa)
rbbp8nlRetinoblastoma binding protein 8-like. (593 aa)
Ppp2r3cProtein phosphatase 2, regulatory subunit B'', gamma. (452 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
psmb1Proteasome subunit beta. (237 aa)
LOC103398252Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (76 aa)
ccne1Cyclin E1; Belongs to the cyclin family. (426 aa)
psmd14Proteasome 26S subunit, non-ATPase 14. (310 aa)
meiobMethionine sulfoxide reductase B1b. (436 aa)
psma1Proteasome subunit alpha type. (266 aa)
wee1Wee1-like protein kinase. (616 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (903 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (293 aa)
psmd5Proteasome 26S subunit, non-ATPase 5. (504 aa)
LOC103385882Cyclin-dependent kinase inhibitor 1A. (167 aa)
PSMD4VWFA domain-containing protein. (375 aa)
LOC103379914Proteasome subunit alpha type. (261 aa)
dbf4DBF4 zinc finger. (528 aa)
rps27aRibosomal protein S27a. (156 aa)
mnat1MNAT1 component of CDK activating kinase. (311 aa)
psme1Proteasome activator subunit 1. (249 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
cdc6Cell division cycle 6 homolog (S. cerevisiae). (526 aa)
mcm4DNA helicase; Belongs to the MCM family. (859 aa)
ENSCSEP00000016476DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (473 aa)
LOC103383890V-akt murine thymoma viral oncogene homolog 3b; Belongs to the protein kinase superfamily. (484 aa)
mcm3DNA helicase; Belongs to the MCM family. (813 aa)
psmb2Proteasome subunit beta. (187 aa)
pola1DNA polymerase. (1429 aa)
psma2Proteasome subunit alpha type. (234 aa)
cables1Cdk5 and Abl enzyme substrate 1. (550 aa)
LOC103382906Uncharacterized protein. (179 aa)
LOC103382905Uncharacterized protein. (171 aa)
ENSCSEP00000018052Uncharacterized protein. (138 aa)
psma3Proteasome subunit alpha type. (255 aa)
PSMC526S proteasome regulatory subunit 8. (398 aa)
ENSCSEP00000009900PI31_Prot_N domain-containing protein. (194 aa)
ENSCSEP00000009964Uncharacterized protein. (85 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (434 aa)
Orc5Origin recognition complex, subunit 5. (435 aa)
ENSCSEP00000011109Proteasome 26S subunit, non-ATPase 8. (257 aa)
LOC103394542Proteasome 26S subunit, non-ATPase 4a. (371 aa)
LOC103389639Proteasome subunit beta. (277 aa)
LOC103394526Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (109 aa)
LOC103399400ANK_REP_REGION domain-containing protein. (81 aa)
ENSCSEP00000012109Metallophos domain-containing protein. (79 aa)
psmd3Proteasome 26S subunit, non-ATPase 3. (520 aa)
LOC103385141Cdk5 and Abl enzyme substrate 2b. (538 aa)
kiaa1468RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1208 aa)
LOC103385164Tyrosine-protein kinase. (506 aa)
ENSCSEP00000013775Uncharacterized protein. (292 aa)
cdkn1bCyclin-dependent kinase inhibitor 1Bb. (184 aa)
psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
psmd12Proteasome 26S subunit, non-ATPase 12. (456 aa)
LOC103379080Cyclin D1; Belongs to the cyclin family. (293 aa)
LOC103398645Proteasome subunit alpha type. (261 aa)
LOC103395242Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (633 aa)
LOC103393606PCI domain-containing protein. (422 aa)
ENSCSEP00000020203DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (315 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (959 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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