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| | YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b; Belongs to the 14-3-3 family. (244 aa) |
| | psmb1 | Proteasome subunit beta. (237 aa) |
| | ccnb3 | Cyclin B3; Belongs to the cyclin family. (419 aa) |
| | rfc4 | Replication factor C (activator 1) 4. (358 aa) |
| | tdrd3 | Tudor domain containing 3. (773 aa) |
| | abraxas1 | Abraxas 1, BRCA1 A complex subunit. (346 aa) |
| | psmd14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | meiob | Methionine sulfoxide reductase B1b. (436 aa) |
| | psma1 | Proteasome subunit alpha type. (266 aa) |
| | wee1 | Wee1-like protein kinase. (616 aa) |
| | orc1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (903 aa) |
| | LOC103377125 | Si:dkey-21a6.5. (269 aa) |
| | psmd5 | Proteasome 26S subunit, non-ATPase 5. (504 aa) |
| | rps27a | Ribosomal protein S27a. (156 aa) |
| | cdk1 | Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (269 aa) |
| | LOC103377546 | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a; Belongs to the 14-3-3 family. (258 aa) |
| | dbf4 | DBF4 zinc finger. (528 aa) |
| | LOC103379914 | Proteasome subunit alpha type. (261 aa) |
| | PSMD4 | VWFA domain-containing protein. (375 aa) |
| | Atm | Non-specific serine/threonine protein kinase. (3052 aa) |
| | orc3 | Origin recognition complex, subunit 3. (719 aa) |
| | cntd2 | Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (393 aa) |
| | babam2 | BRISC and BRCA1 A complex member 2. (386 aa) |
| | mcm7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa) |
| | ENSCSEP00000005051 | Histone H2B; Belongs to the histone H2B family. (112 aa) |
| | LOC103380040 | Wee1-like protein kinase. (546 aa) |
| | atr | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2429 aa) |
| | ENSCSEP00000006274 | Histone H2B; Belongs to the histone H2B family. (114 aa) |
| | ENSCSEP00000006303 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (95 aa) |
| | cdk2 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | psma5 | Proteasome subunit alpha type. (241 aa) |
| | RCBTB1 | Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (637 aa) |
| | ywhae | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (254 aa) |
| | cdca7 | Cell division cycle associated 7a. (401 aa) |
| | psmd6 | Proteasome 26S subunit, non-ATPase 6. (389 aa) |
| | psmd7 | Proteasome 26S subunit, non-ATPase 7. (330 aa) |
| | pias4 | Protein inhibitor of activated STAT, 4a. (499 aa) |
| | LOC103380153 | Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (154 aa) |
| | psmb6 | Proteasome subunit beta. (234 aa) |
| | psmd13 | Proteasome 26S subunit, non-ATPase 13. (391 aa) |
| | Rnf169 | Ring finger protein 169. (665 aa) |
| | psme4 | Proteasome activator subunit 4a. (1847 aa) |
| | kxd1 | KxDL motif containing 1. (180 aa) |
| | LOC103381415 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (398 aa) |
| | PSMC5 | 26S proteasome regulatory subunit 8. (398 aa) |
| | ENSCSEP00000009900 | PI31_Prot_N domain-containing protein. (194 aa) |
| | top3a | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1037 aa) |
| | ENSCSEP00000009964 | Uncharacterized protein. (85 aa) |
| | ENSCSEP00000010388 | Histone H2B; Belongs to the histone H2B family. (122 aa) |
| | ENSCSEP00000010689 | Histone H2B; Belongs to the histone H2B family. (114 aa) |
| | orc4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (434 aa) |
| | ENSCSEP00000010737 | Histone H2B; Belongs to the histone H2B family. (117 aa) |
| | rcbtb2 | Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (554 aa) |
| | Orc5 | Origin recognition complex, subunit 5. (435 aa) |
| | rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (394 aa) |
| | ENSCSEP00000011109 | Proteasome 26S subunit, non-ATPase 8. (257 aa) |
| | LOC103394542 | Proteasome 26S subunit, non-ATPase 4a. (371 aa) |
| | brca1 | Uncharacterized protein. (1217 aa) |
| | LOC103389639 | Proteasome subunit beta. (277 aa) |
| | LOC103399400 | ANK_REP_REGION domain-containing protein. (81 aa) |
| | ENSCSEP00000011696 | Uncharacterized protein. (103 aa) |
| | rhno1 | Si:ch73-352p4.5. (301 aa) |
| | ENSCSEP00000012570 | Histone H2A; Belongs to the histone H2A family. (218 aa) |
| | chek2 | Checkpoint kinase 2. (550 aa) |
| | psmd3 | Proteasome 26S subunit, non-ATPase 3. (520 aa) |
| | LOC103379018 | Cyclin B2; Belongs to the cyclin family. (394 aa) |
| | ENSCSEP00000013775 | Uncharacterized protein. (292 aa) |
| | cdca7l | Cell division cycle associated 7b. (416 aa) |
| | Rnf168 | RING-type domain-containing protein. (117 aa) |
| | ENSCSEP00000014019 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (89 aa) |
| | rad17 | RAD17 checkpoint clamp loader component. (640 aa) |
| | ENSCSEP00000014113 | Histone domain-containing protein; Belongs to the histone H2B family. (109 aa) |
| | pkmyt1 | Protein kinase, membrane associated tyrosine/threonine 1. (586 aa) |
| | psme1 | Proteasome activator subunit 1. (249 aa) |
| | exd2 | Exonuclease 3'-5' domain containing 2. (728 aa) |
| | tp53bp1 | Tumor protein p53 binding protein, 1. (1101 aa) |
| | cdc6 | Cell division cycle 6 homolog (S. cerevisiae). (526 aa) |
| | LOC103382819 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa) |
| | atrip | Uncharacterized protein. (600 aa) |
| | chek1 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (488 aa) |
| | LOC103381548 | Uncharacterized protein. (1808 aa) |
| | ube2v2 | Ubiquitin-conjugating enzyme E2 variant 2. (158 aa) |
| | mcm4 | DNA helicase; Belongs to the MCM family. (859 aa) |
| | Rad9b | Uncharacterized protein. (177 aa) |
| | mcm3 | DNA helicase; Belongs to the MCM family. (813 aa) |
| | psmb2 | Proteasome subunit beta. (187 aa) |
| | CLSPN | Claspin. (1352 aa) |
| | LOC103395178 | 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1; Belongs to the 14-3-3 family. (247 aa) |
| | LOC103378165 | 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2; Belongs to the 14-3-3 family. (247 aa) |
| | LOC103396322 | Histone H2B; Belongs to the histone H2B family. (116 aa) |
| | psma8 | Proteasome subunit alpha type. (251 aa) |
| | psma2 | Proteasome subunit alpha type. (234 aa) |
| | rbbp8 | CtIP_N domain-containing protein. (539 aa) |
| | ENSCSEP00000018191 | SAE2 domain-containing protein. (90 aa) |
| | psma3 | Proteasome subunit alpha type. (255 aa) |
| | psmc4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | psmd12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) |
| | rfc3 | Replication factor C (activator 1) 3. (356 aa) |
| | rmi1 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (642 aa) |
| | LOC103398645 | Proteasome subunit alpha type. (261 aa) |
| | LOC103395242 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (633 aa) |
| | LOC103393606 | PCI domain-containing protein. (422 aa) |
| | rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa) |
| | ywhaz | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa) |
| | wdr41 | WD repeat domain 41. (450 aa) |
| | blm | BLM RecQ like helicase. (1300 aa) |
| | Whsc1 | Nuclear receptor binding SET domain protein 2. (931 aa) |
| | dna2 | DNA replication helicase/nuclease 2. (1185 aa) |
| | psmd1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (959 aa) |
| | slf1 | Uncharacterized protein. (788 aa) |
| | ENSCSEP00000022777 | DNA helicase; Belongs to the MCM family. (683 aa) |
| | kat5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (540 aa) |
| | ENSCSEP00000023029 | Histone H2B; Belongs to the histone H2B family. (113 aa) |
| | ENSCSEP00000023037 | annotation not available (67 aa) |
| | HIST1H4J | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa) |
| | ENSCSEP00000023079 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa) |
| | ENSCSEP00000023097 | Histone H2B; Belongs to the histone H2B family. (114 aa) |
| | ENSCSEP00000023236 | RecQ helicase-like 4. (807 aa) |
| | LOC103378260 | Proteasome subunit alpha type. (267 aa) |
| | psmd9 | Proteasome 26S subunit, non-ATPase 9. (212 aa) |
| | rad50 | RAD50 homolog, double strand break repair protein. (1319 aa) |
| | LOC103381864 | Proteasome 26S subunit, non-ATPase 11b. (422 aa) |
| | LOC103386524 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (244 aa) |
| | ENSCSEP00000023783 | PIEZO domain-containing protein. (1341 aa) |
| | ENSCSEP00000023807 | Piezo_RRas_bdg domain-containing protein. (584 aa) |
| | LOC103394270 | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; Belongs to the 14-3-3 family. (247 aa) |
| | psme2 | Proteasome activator subunit 2. (245 aa) |
| | psme3 | Proteasome activator subunit 3. (240 aa) |
| | ccnb1 | Cyclin B1; Belongs to the cyclin family. (400 aa) |
| | Cdc25b | Rhodanese domain-containing protein. (568 aa) |
| | psmc6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (407 aa) |
| | ENSCSEP00000024591 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa) |
| | Mcm9 | Uncharacterized protein. (131 aa) |
| | ENSCSEP00000025093 | Uncharacterized protein. (194 aa) |
| | UBB | Ubiquitin B. (744 aa) |
| | psmb3 | Proteasome subunit beta. (205 aa) |
| | ENSCSEP00000025964 | XPGN domain-containing protein. (140 aa) |
| | exo1 | Exonuclease 1. (597 aa) |
| | babam1 | BRISC and BRCA1 A complex member 1. (316 aa) |
| | LOC103382982 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa) |
| | LOC103389086 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (144 aa) |
| | ankrd12 | Ankyrin repeat domain 12. (1932 aa) |
| | mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (718 aa) |
| | PIEZO2 | Piezo-type mechanosensitive ion channel component. (2783 aa) |
| | mcm8 | Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (859 aa) |
| | brcc3 | BRCA1/BRCA2-containing complex, subunit 3. (236 aa) |
| | ENSCSEP00000027503 | Piezo-type mechanosensitive ion channel component. (2315 aa) |
| | cdc7 | Cell division cycle 7 homolog (S. cerevisiae). (582 aa) |
| | ENSCSEP00000027862 | Ankyrin repeat domain 11. (2775 aa) |
| | LOC103389149 | Proteasome subunit beta. (276 aa) |
| | hus1 | Checkpoint protein; Belongs to the HUS1 family. (281 aa) |
| | psmd10 | Proteasome 26S subunit, non-ATPase 10. (209 aa) |
| | Mcm6 | DNA helicase; Belongs to the MCM family. (688 aa) |
| | psmc1 | Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (440 aa) |
| | psma6 | Proteasome subunit alpha type. (246 aa) |
| | rpa2 | Replication protein A2. (274 aa) |
| | rfc2 | Replication factor C (activator 1) 2. (355 aa) |
| | psmb8 | Proteasome subunit beta. (271 aa) |
| | LOC103393840 | Proteasome subunit beta 12. (217 aa) |
| | topbp1 | DNA topoisomerase II binding protein 1. (1517 aa) |
| | psmb4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (226 aa) |
| | cdc45 | CDC45 cell division cycle 45 homolog (S. cerevisiae). (568 aa) |
| | psmc3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (404 aa) |
| | ENSCSEP00000030782 | Uncharacterized protein. (506 aa) |
| | ENSCSEP00000030790 | Uncharacterized protein. (303 aa) |
| | rad1 | RAD1 homolog (S. pombe). (277 aa) |
| | ENSCSEP00000031260 | Uncharacterized protein; Belongs to the histone H2B family. (112 aa) |
| | Mcm10 | Zf-primase domain-containing protein. (203 aa) |
| | LOC103386842 | Proteasome inhibitor subunit 1. (280 aa) |
| | rnf8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (540 aa) |
| | mcm2 | DNA helicase; Belongs to the MCM family. (885 aa) |
| | rfc5 | Replication factor C (activator 1) 5. (338 aa) |
| | LOC103396604 | Proteasome subunit beta. (278 aa) |
| | PSMB11 | Proteasome subunit beta. (304 aa) |
| | ENSCSEP00000033017 | GTSE1_N domain-containing protein. (700 aa) |
| | rmi2 | RecQ mediated genome instability 2. (163 aa) |
| | LOC103385609 | Ubiquitin-conjugating enzyme E2 variant 1. (147 aa) |
