30 items (Cynoglossus semilaevis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	LOC103389143	Dual specificity phosphatase 11 (RNA/RNP complex 1-interacting). (360 aa)
	mnat1	MNAT1 component of CDK activating kinase. (311 aa)
	polr2c	Polymerase (RNA) II (DNA directed) polypeptide C. (275 aa)
	polr2l	Polymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
	polr2i	Polymerase (RNA) II (DNA directed) polypeptide I. (287 aa)
	polr2a	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1965 aa)
	rngtt	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (601 aa)
	polr2b	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
	ercc2	Excision repair cross-complementation group 2. (760 aa)
	polr2d	Polymerase (RNA) II (DNA directed) polypeptide D. (144 aa)
	gtf2h1	General transcription factor IIH, polypeptide 1. (551 aa)
	polr2f	Polymerase (RNA) II (DNA directed) polypeptide F. (127 aa)
	POLR2E	RNA polymerase II subunit E. (229 aa)
	polr2g	Polymerase (RNA) II (DNA directed) polypeptide G-like. (190 aa)
	NCBP1	Nuclear cap binding protein subunit 1. (822 aa)
	LOC103392281	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (277 aa)
	gtf2f1	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (533 aa)
	gtf2h3	General transcription factor IIH, polypeptide 3. (327 aa)
	polr2h	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (155 aa)
	supt5h	Transcription elongation factor SPT5. (991 aa)
	LOC103397561	General transcription factor IIH subunit. (414 aa)
	cdk7	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (344 aa)
	gtf2f2	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (270 aa)
	ercc3	Excision repair cross-complementation group 3. (785 aa)
	ENSCSEP00000026853	Uncharacterized protein. (795 aa)
	polr2k	Polymerase (RNA) II (DNA directed) polypeptide K. (58 aa)
	ENSCSEP00000028466	RNA (guanine-7-) methyltransferase. (295 aa)
	gtf2h4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (461 aa)
	ENSCSEP00000029688	TYR_PHOSPHATASE_2 domain-containing protein. (247 aa)
	polr2j	Polymerase (RNA) II (DNA directed) polypeptide J. (117 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCSEP00000026853	ENSCSEP00000028466	ENSCSEP00000026853	ENSCSEP00000028466	Uncharacterized protein.	RNA (guanine-7-) methyltransferase.	0.840
ENSCSEP00000026853	ENSCSEP00000029688	ENSCSEP00000026853	ENSCSEP00000029688	Uncharacterized protein.	TYR_PHOSPHATASE_2 domain-containing protein.	0.802
ENSCSEP00000026853	LOC103389143	ENSCSEP00000026853	ENSCSEP00000027911	Uncharacterized protein.	Dual specificity phosphatase 11 (RNA/RNP complex 1-interacting).	0.802
ENSCSEP00000026853	LOC103392281	ENSCSEP00000026853	ENSCSEP00000020853	Uncharacterized protein.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.851
ENSCSEP00000026853	NCBP1	ENSCSEP00000026853	ENSCSEP00000019395	Uncharacterized protein.	Nuclear cap binding protein subunit 1.	0.718
ENSCSEP00000026853	POLR2E	ENSCSEP00000026853	ENSCSEP00000011072	Uncharacterized protein.	RNA polymerase II subunit E.	0.969
ENSCSEP00000026853	cdk7	ENSCSEP00000026853	ENSCSEP00000025765	Uncharacterized protein.	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily.	0.706
ENSCSEP00000026853	ercc3	ENSCSEP00000026853	ENSCSEP00000025795	Uncharacterized protein.	Excision repair cross-complementation group 3.	0.652
ENSCSEP00000026853	gtf2f1	ENSCSEP00000026853	ENSCSEP00000020911	Uncharacterized protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.731
ENSCSEP00000026853	gtf2f2	ENSCSEP00000026853	ENSCSEP00000025766	Uncharacterized protein.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.851
ENSCSEP00000026853	gtf2h1	ENSCSEP00000026853	ENSCSEP00000010037	Uncharacterized protein.	General transcription factor IIH, polypeptide 1.	0.802
ENSCSEP00000026853	gtf2h3	ENSCSEP00000026853	ENSCSEP00000023306	Uncharacterized protein.	General transcription factor IIH, polypeptide 3.	0.719
ENSCSEP00000026853	gtf2h4	ENSCSEP00000026853	ENSCSEP00000029297	Uncharacterized protein.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.753
ENSCSEP00000026853	mnat1	ENSCSEP00000026853	ENSCSEP00000002272	Uncharacterized protein.	MNAT1 component of CDK activating kinase.	0.699
ENSCSEP00000026853	polr2a	ENSCSEP00000026853	ENSCSEP00000004081	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.970
ENSCSEP00000026853	polr2b	ENSCSEP00000026853	ENSCSEP00000008316	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.973
ENSCSEP00000026853	polr2c	ENSCSEP00000026853	ENSCSEP00000002623	Uncharacterized protein.	Polymerase (RNA) II (DNA directed) polypeptide C.	0.969
ENSCSEP00000026853	polr2d	ENSCSEP00000026853	ENSCSEP00000009584	Uncharacterized protein.	Polymerase (RNA) II (DNA directed) polypeptide D.	0.968
ENSCSEP00000026853	polr2f	ENSCSEP00000026853	ENSCSEP00000010669	Uncharacterized protein.	Polymerase (RNA) II (DNA directed) polypeptide F.	0.961
ENSCSEP00000026853	polr2g	ENSCSEP00000026853	ENSCSEP00000018850	Uncharacterized protein.	Polymerase (RNA) II (DNA directed) polypeptide G-like.	0.969