STRINGSTRING
ENSCSEP00000012583 ENSCSEP00000012583 LOC103397939 LOC103397939 kpnb1 kpnb1 LOC103388483 LOC103388483 ENSCSEP00000011814 ENSCSEP00000011814 ENSCSEP00000011692 ENSCSEP00000011692 LOC103376747 LOC103376747 mvd mvd LOC103394548 LOC103394548 ENSCSEP00000011030 ENSCSEP00000011030 SREBF2 SREBF2 ran ran LOC103380225 LOC103380225 LOC103378914 LOC103378914 LOC103393291 LOC103393291 OSBPL2 OSBPL2 nr1h4 nr1h4 stard5 stard5 pias4 pias4 dhcr24 dhcr24 LOC103389439 LOC103389439 LOC103389542 LOC103389542 rxra rxra LOC103384911 LOC103384911 LOC103386109 LOC103386109 LOC103388433 LOC103388433 LOC103384850 LOC103384850 LOC103386049 LOC103386049 nfya nfya ENSCSEP00000006012 ENSCSEP00000006012 LOC103386014 LOC103386014 hsd11b2 hsd11b2 ENSCSEP00000005641 ENSCSEP00000005641 srd5a3 srd5a3 LOC103384745 LOC103384745 ENSCSEP00000005180 ENSCSEP00000005180 nfyb nfyb ENSCSEP00000004975 ENSCSEP00000004975 LOC103378812 LOC103378812 arv1 arv1 hsdl1 hsdl1 LOC103381159 LOC103381159 LOC103378402 LOC103378402 LOC103383557 LOC103383557 osbpl6 osbpl6 Hsd11b1l Hsd11b1l ENSCSEP00000004266 ENSCSEP00000004266 PTGIS PTGIS FADS6 FADS6 cga cga LOC103386984 LOC103386984 rusc1 rusc1 fdps fdps LOC103383449 LOC103383449 LOC103383468 LOC103383468 LOC103390476 LOC103390476 LOC103386947 LOC103386947 LOC103382280 LOC103382280 tspo tspo ch25h ch25h Insig1 Insig1 hsd17b12 hsd17b12 amacr amacr LOC103398772 LOC103398772 podn podn LOC103385737 LOC103385737 ebp ebp mbtps2 mbtps2 dhcr7 dhcr7 LOC103379744 LOC103379744 LOC103376981 LOC103376981 ENSCSEP00000016989 ENSCSEP00000016989 Scp2 Scp2 LOC107988900 LOC107988900 LOC103382877 LOC103382877 LOC103382863 LOC103382863 LOC103398034 LOC103398034 LOC103398029 LOC103398029 sqle sqle LOC103379286 LOC103379286 HSD17B7 HSD17B7 slc10a1 slc10a1 idi1 idi1 msmo1 msmo1 LOC103392195 LOC103392195 srd5a1 srd5a1 ENSCSEP00000017828 ENSCSEP00000017828 OSBPL1A OSBPL1A ube2i ube2i sdr42e1 sdr42e1 LOC103389902 LOC103389902 LOC103396792 LOC103396792 LOC103396791 LOC103396791 hsd3b7 hsd3b7 LOC103385600 LOC103385600 stard3nl stard3nl Hsd17b2 Hsd17b2 sdr16c5 sdr16c5 LOC103383286 LOC103383286 LOC103392551 LOC103392551 LOC103380837 LOC103380837 fdft1 fdft1 fdxr fdxr ENSCSEP00000031953 ENSCSEP00000031953 ENSCSEP00000031943 ENSCSEP00000031943 hsdl2 hsdl2 pmvk pmvk LOC103392506 LOC103392506 LOC103386736 LOC103386736 LOC103380768 LOC103380768 ENSCSEP00000029757 ENSCSEP00000029757 LOC103380731 LOC103380731 LOC103380705 LOC103380705 lbr lbr hsd17b4 hsd17b4 sugct sugct LOC103396185 LOC103396185 LOC103378502 LOC103378502 LOC103393769 LOC103393769 LOC103389147 LOC103389147 mvk mvk LOC103398902 LOC103398902 LOC103395421 LOC103395421 PLPP7 PLPP7 hsd17b1 hsd17b1 nfyc nfyc LOC103396539 LOC103396539 LOC103387725 LOC103387725 LOC103381921 LOC103381921 stard3 stard3 LOC103398814 LOC103398814 faxdc2 faxdc2 ENSCSEP00000025579 ENSCSEP00000025579 ADGRD1 ADGRD1 cdcp2 cdcp2 ENSCSEP00000025149 ENSCSEP00000025149 ENSCSEP00000025116 ENSCSEP00000025116 sc5d sc5d srebf1 srebf1 tm7sf2 tm7sf2 osbpl7 osbpl7 LOC103398716 LOC103398716 LOC103382927 LOC103382927 nsdhl nsdhl LOC103394220 LOC103394220 mbtps1 mbtps1 POMC POMC LOC103382928 LOC103382928 scap scap fdx2 fdx2 ncoa2 ncoa2 SLCO1C1 SLCO1C1 FDX1 FDX1 LOC103398656 LOC103398656 osbpl9 osbpl9 ggps1 ggps1 sumo2 sumo2 LOC103393550 LOC103393550 LOC103380466 LOC103380466 LOC103396384 LOC103396384 CYP19A1 CYP19A1 LOC103379054 LOC103379054 LOC103397457 LOC103397457 hsd3b1 hsd3b1 ebpl ebpl Cubn Cubn AKR1D1 AKR1D1 LOC103395713 LOC103395713 acot8 acot8 hmgcr hmgcr ENSCSEP00000013539 ENSCSEP00000013539 LOC103396908 LOC103396908 ENSCSEP00000012672 ENSCSEP00000012672
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSCSEP00000012583Uncharacterized protein. (90 aa)
LOC103397939acidPPc domain-containing protein. (297 aa)
kpnb1Karyopherin (importin) beta 1. (852 aa)
LOC103388483Cytochrome P450, family 21, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family. (523 aa)
ENSCSEP00000011814Uncharacterized protein. (78 aa)
ENSCSEP00000011692Ubiquitin-like domain-containing protein. (102 aa)
LOC103376747Hydroxysteroid (17-beta) dehydrogenase 7. (336 aa)
mvdDiphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (403 aa)
LOC103394548Cytochrome P450, family 51; Belongs to the cytochrome P450 family. (514 aa)
ENSCSEP00000011030Uncharacterized protein. (232 aa)
SREBF2Sterol regulatory element binding transcription factor 2. (579 aa)
ranGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (259 aa)
LOC103380225Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (497 aa)
LOC103378914Cytochrome P450, family 19, subfamily A, polypeptide 1a; Belongs to the cytochrome P450 family. (554 aa)
LOC103393291Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
OSBPL2Oxysterol-binding protein; Belongs to the OSBP family. (472 aa)
nr1h4Nuclear receptor subfamily 1, group H, member 4. (468 aa)
stard5StAR-related lipid transfer (START) domain containing 5. (211 aa)
pias4Protein inhibitor of activated STAT, 4a. (499 aa)
dhcr2424-dehydrocholesterol reductase. (507 aa)
LOC103389439Cytochrome P450, family 17, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family. (524 aa)
LOC103389542Si:ch211-113j14.1; Belongs to the cytochrome P450 family. (542 aa)
rxraRetinoid X receptor, alpha a. (498 aa)
LOC103384911Nuclear receptor subfamily 1, group H, member 5. (471 aa)
LOC103386109Vitamin D receptor b. (425 aa)
LOC103388433Oxysterol-binding protein; Belongs to the OSBP family. (879 aa)
LOC103384850Si:dkey-16n15.6. (415 aa)
LOC103386049Cytochrome P450, family 27, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (511 aa)
nfyaNuclear transcription factor Y, alpha, like. (354 aa)
ENSCSEP00000006012Oxysterol-binding protein; Belongs to the OSBP family. (840 aa)
LOC103386014Uncharacterized protein. (502 aa)
hsd11b2Hydroxysteroid (11-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (437 aa)
ENSCSEP00000005641Uncharacterized protein. (1183 aa)
srd5a3Steroid 5 alpha-reductase 3. (311 aa)
LOC103384745Uncharacterized protein. (411 aa)
ENSCSEP00000005180Cytochrome P450, family 11, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (598 aa)
nfybNuclear transcription factor Y, beta a. (203 aa)
ENSCSEP00000004975Uncharacterized protein. (415 aa)
LOC103378812Hydroxysteroid (17-beta) dehydrogenase 12b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa)
arv1ARV1 homolog, fatty acid homeostasis modulator. (239 aa)
hsdl1Hydroxysteroid dehydrogenase like 1. (325 aa)
LOC103381159Nuclear receptor coactivator 1. (1235 aa)
LOC103378402Small ubiquitin-related modifier. (94 aa)
LOC103383557Small ubiquitin-related modifier. (96 aa)
osbpl6Oxysterol-binding protein; Belongs to the OSBP family. (916 aa)
Hsd11b1lHydroxysteroid (11-beta) dehydrogenase 1-like a. (288 aa)
ENSCSEP00000004266Hydroxysteroid (11-beta) dehydrogenase 1-like a. (297 aa)
PTGISProstaglandin I2 synthase; Belongs to the cytochrome P450 family. (486 aa)
FADS6Fatty acid desaturase 6. (346 aa)
cgaGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (139 aa)
LOC103386984Oxysterol-binding protein; Belongs to the OSBP family. (787 aa)
rusc1Uncharacterized protein. (1843 aa)
fdpsUncharacterized protein; Belongs to the FPP/GGPP synthase family. (358 aa)
LOC103383449Retinol dehydrogenase 8b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
LOC103383468Oxysterol-binding protein; Belongs to the OSBP family. (767 aa)
LOC103390476Oxysterol-binding protein; Belongs to the OSBP family. (536 aa)
LOC103386947Luteinizing hormone, beta polypeptide. (158 aa)
LOC103382280Dehydrogenase/reductase (SDR family) member 7Cb. (311 aa)
tspoTranslocator protein. (232 aa)
ch25hCholesterol 25-hydroxylase; Belongs to the sterol desaturase family. (251 aa)
Insig1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. (310 aa)
hsd17b12Hydroxysteroid (17-beta) dehydrogenase 12a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa)
amacrAlpha-methylacyl-CoA racemase. (382 aa)
LOC103398772Sterol carrier protein 2b. (135 aa)
podnPodocan. (600 aa)
LOC103385737Prostaglandin I2 (prostacyclin) synthase; Belongs to the cytochrome P450 family. (453 aa)
ebpEBP cholestenol delta-isomerase. (232 aa)
mbtps2Membrane-bound transcription factor peptidase, site 2. (498 aa)
dhcr77-dehydrocholesterol reductase. (471 aa)
LOC103379744Zgc:56622. (323 aa)
LOC103376981Solute carrier family 51 alpha subunit. (325 aa)
ENSCSEP00000016989Uncharacterized protein. (1785 aa)
Scp2Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (362 aa)
LOC107988900Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 2. (316 aa)
LOC103382877Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 2. (311 aa)
LOC103382863Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 1. (303 aa)
LOC103398034Steroidogenic acute regulatory protein. (283 aa)
LOC103398029Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7; Belongs to the serpin family. (412 aa)
sqleSqualene epoxidase a. (568 aa)
LOC103379286Cytochrome P450, family 2, subfamily R, polypeptide 1; Belongs to the cytochrome P450 family. (520 aa)
HSD17B7Hydroxysteroid 17-beta dehydrogenase 7. (345 aa)
slc10a1Uncharacterized protein. (360 aa)
idi1Isopentenyl-diphosphate delta isomerase 1. (257 aa)
msmo1Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. (291 aa)
LOC103392195Small ubiquitin-related modifier. (100 aa)
srd5a1S5A_REDUCTASE domain-containing protein. (281 aa)
ENSCSEP00000017828Cholesterol 25-hydroxylase like 2; Belongs to the sterol desaturase family. (305 aa)
OSBPL1AOxysterol-binding protein; Belongs to the OSBP family. (932 aa)
ube2iUbiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
sdr42e1Short chain dehydrogenase/reductase family 42E, member 1. (417 aa)
LOC1033899023-hydroxy-3-methylglutaryl coenzyme A reductase. (873 aa)
LOC103396792Uncharacterized protein. (442 aa)
LOC103396791Uncharacterized protein. (446 aa)
hsd3b7Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase. (408 aa)
LOC103385600Oxysterol-binding protein; Belongs to the OSBP family. (450 aa)
stard3nlSTARD3 N-terminal like. (199 aa)
Hsd17b2Hydroxysteroid (17-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (374 aa)
sdr16c5Short chain dehydrogenase/reductase family 16C, member 5a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (306 aa)
LOC1033832863-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (256 aa)
LOC103392551Hydroxysteroid (17-beta) dehydrogenase 14. (264 aa)
LOC103380837Uncharacterized protein. (238 aa)
fdft1Farnesyl-diphosphate farnesyltransferase 1. (418 aa)
fdxrNADPH:adrenodoxin oxidoreductase, mitochondrial. (480 aa)
ENSCSEP00000031953Uncharacterized protein. (187 aa)
ENSCSEP00000031943Uncharacterized protein. (80 aa)
hsdl2Hydroxysteroid dehydrogenase like 2. (418 aa)
pmvkPhosphomevalonate kinase. (203 aa)
LOC103392506Retinol dehydrogenase 8a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
LOC103386736Cytochrome P450, family 24, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (513 aa)
LOC103380768Cytochrome P450, family 27, subfamily A, polypeptide 7; Belongs to the cytochrome P450 family. (520 aa)
ENSCSEP00000029757Metal-regulatory transcription factor 1. (766 aa)
LOC103380731SERPIN domain-containing protein; Belongs to the serpin family. (450 aa)
LOC103380705Cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 4. (508 aa)
lbrLamin B receptor. (614 aa)
hsd17b4Hydroxysteroid (17-beta) dehydrogenase 4. (725 aa)
sugctSuccinyl-CoA:glutarate-CoA transferase. (424 aa)
LOC103396185acidPPc domain-containing protein. (266 aa)
LOC103378502Solute carrier organic anion transporter family member. (705 aa)
LOC103393769POMC-b. (178 aa)
LOC1033891473-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (519 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (397 aa)
LOC103398902Hydroxysteroid (17-beta) dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (313 aa)
LOC103395421Hydroxysteroid (20-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa)
PLPP7Phospholipid phosphatase 7 (inactive). (288 aa)
hsd17b1Hydroxysteroid (17-beta) dehydrogenase 1. (290 aa)
nfycNuclear transcription factor Y, gamma. (345 aa)
LOC103396539Cytochrome P450, family 7, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (513 aa)
LOC103387725Cytochrome P450, family 17, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (530 aa)
LOC103381921START domain-containing protein. (271 aa)
stard3StAR-related lipid transfer (START) domain containing 3. (451 aa)
LOC103398814Cytochrome P450, family 27, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (513 aa)
faxdc2Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. (345 aa)
ENSCSEP00000025579Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (696 aa)
ADGRD1Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family. (770 aa)
cdcp2CUB domain containing protein 2. (391 aa)
ENSCSEP00000025149CUB domain-containing protein. (127 aa)
ENSCSEP00000025116RIMS binding protein 2. (1271 aa)
sc5dSterol-C5-desaturase; Belongs to the sterol desaturase family. (294 aa)
srebf1Sterol regulatory element binding transcription factor 1. (1172 aa)
tm7sf2Transmembrane 7 superfamily member 2. (425 aa)
osbpl7Oxysterol-binding protein; Belongs to the OSBP family. (840 aa)
LOC103398716Uncharacterized protein. (547 aa)
LOC103382927Solute carrier organic anion transporter family member. (711 aa)
nsdhlNAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (365 aa)
LOC103394220Oxysterol-binding protein; Belongs to the OSBP family. (817 aa)
mbtps1Membrane-bound transcription factor peptidase, site 1. (1042 aa)
POMCProopiomelanocortin. (213 aa)
LOC103382928Solute carrier organic anion transporter family member. (684 aa)
scapSREBF chaperone. (1275 aa)
fdx2Ferredoxin 2. (188 aa)
ncoa2Nuclear receptor coactivator 2. (1552 aa)
SLCO1C1Solute carrier organic anion transporter family member. (663 aa)
FDX1Ferredoxin 1. (168 aa)
LOC103398656Oxysterol-binding protein; Belongs to the OSBP family. (784 aa)
osbpl9Oxysterol-binding protein; Belongs to the OSBP family. (740 aa)
ggps1Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. (317 aa)
sumo2Ubiquitin-like domain-containing protein. (149 aa)
LOC103393550Oxysterol-binding protein; Belongs to the OSBP family. (900 aa)
LOC103380466Uncharacterized protein. (620 aa)
LOC103396384Cytochrome P450, family 8, subfamily B, polypeptide 2; Belongs to the cytochrome P450 family. (478 aa)
CYP19A1Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (498 aa)
LOC103379054Solute carrier family 27 member 2a. (620 aa)
LOC103397457Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family. (262 aa)
hsd3b1Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family. (373 aa)
ebplEBP like. (207 aa)
CubnCubilin (intrinsic factor-cobalamin receptor). (3606 aa)
AKR1D1Aldo-keto reductase family 1 member D1. (326 aa)
LOC103395713Uncharacterized protein. (366 aa)
acot8Acyl-CoA thioesterase 8. (332 aa)
hmgcr3-hydroxy-3-methylglutaryl coenzyme A reductase. (883 aa)
ENSCSEP00000013539Cholesterol 25-hydroxylase like 1, tandem duplicate 2; Belongs to the sterol desaturase family. (275 aa)
LOC103396908Steroidogenic acute regulatory protein. (283 aa)
ENSCSEP00000012672Phospholipid phosphatase 6. (160 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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