48 items (Cynoglossus semilaevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ldlrap1	Low density lipoprotein receptor adaptor protein 1b. (312 aa)
	npc2	Niemann-Pick disease, type C2. (151 aa)
	LOC103386604	High density lipoprotein binding protein b. (1267 aa)
	LOC103378667	Ig-like domain-containing protein. (718 aa)
	ENSCSEP00000001678	Uncharacterized protein. (418 aa)
	vldlr	Very low density lipoprotein receptor. (882 aa)
	ENSCSEP00000002382	TSNAXIP1_N domain-containing protein. (430 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	LOC103382254	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (414 aa)
	ildr2	Immunoglobulin-like domain containing receptor 2. (674 aa)
	pcsk9	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (597 aa)
	kxd1	KxDL motif containing 1. (180 aa)
	LOC103378929	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (960 aa)
	scarb1	Scavenger receptor class B, member 1; Belongs to the CD36 family. (507 aa)
	ap2s1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	LOC103392855	Vitellogenin 3, phosvitinless. (1271 aa)
	hdlbp	High density lipoprotein binding protein a. (1266 aa)
	LOC103379249	Si:ch211-71n6.4. (590 aa)
	LOC103395083	AP complex subunit beta. (953 aa)
	Cubn	Cubilin (intrinsic factor-cobalamin receptor). (3606 aa)
	LOC103383992	EGF-like domain-containing protein. (889 aa)
	LOC103393985	Apolipoprotein Ea. (253 aa)
	ENSCSEP00000016631	O-acyltransferase. (434 aa)
	amn	Amnion associated transmembrane protein. (474 aa)
	npc1	Niemann-Pick disease, type C1. (1272 aa)
	ap2a1	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (904 aa)
	LOC103394110	Low density lipoprotein receptor adaptor protein 1a. (303 aa)
	ENSCSEP00000019274	Ig-like domain-containing protein. (186 aa)
	ap2m1	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (442 aa)
	nr1h3	Nuclear receptor subfamily 1, group H, member 3. (462 aa)
	LOC103392297	Uncharacterized protein. (1651 aa)
	clta	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (230 aa)
	ENSCSEP00000020503	Uncharacterized protein. (1571 aa)
	LOC103393235	O-acyltransferase. (567 aa)
	LOC103380524	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (560 aa)
	LOC103378271	Uncharacterized protein. (256 aa)
	ENSCSEP00000023105	Low density lipoprotein receptor a. (852 aa)
	ENSCSEP00000023616	Uncharacterized protein. (78 aa)
	LOC103389012	Apolipoprotein Eb. (346 aa)
	ENSCSEP00000023759	Ubiquitin-like domain-containing protein. (92 aa)
	apob	Apolipoprotein Ba. (4379 aa)
	ENSCSEP00000025149	CUB domain-containing protein. (127 aa)
	cdcp2	CUB domain containing protein 2. (391 aa)
	UBB	Ubiquitin B. (744 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (151 aa)
	ENSCSEP00000027680	Myosin regulatory light chain interacting protein a. (485 aa)
	ENSCSEP00000032636	Vitellogenin domain-containing protein. (722 aa)
	LOC103380907	Apolipoprotein Bb, tandem duplicate 2. (3802 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cubn	amn	ENSCSEP00000014233	ENSCSEP00000017007	Cubilin (intrinsic factor-cobalamin receptor).	Amnion associated transmembrane protein.	0.890
ENSCSEP00000002382	LOC103395083	ENSCSEP00000002382	ENSCSEP00000013981	TSNAXIP1_N domain-containing protein.	AP complex subunit beta.	0.749
ENSCSEP00000002382	ap2a1	ENSCSEP00000002382	ENSCSEP00000018399	TSNAXIP1_N domain-containing protein.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.772
ENSCSEP00000002382	ap2m1	ENSCSEP00000002382	ENSCSEP00000019465	TSNAXIP1_N domain-containing protein.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.727
ENSCSEP00000002382	ap2s1	ENSCSEP00000002382	ENSCSEP00000012769	TSNAXIP1_N domain-containing protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.693
ENSCSEP00000002382	clta	ENSCSEP00000002382	ENSCSEP00000020143	TSNAXIP1_N domain-containing protein.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.833
ENSCSEP00000002382	rps27a	ENSCSEP00000002382	ENSCSEP00000002392	TSNAXIP1_N domain-containing protein.	Ribosomal protein S27a.	0.501
ENSCSEP00000016631	LOC103382254	ENSCSEP00000016631	ENSCSEP00000002902	O-acyltransferase.	Lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.402
ENSCSEP00000020503	ENSCSEP00000023616	ENSCSEP00000020503	ENSCSEP00000023616	Uncharacterized protein.	Uncharacterized protein.	0.514
ENSCSEP00000020503	LOC103378271	ENSCSEP00000020503	ENSCSEP00000023088	Uncharacterized protein.	Uncharacterized protein.	0.646
ENSCSEP00000020503	LOC103382254	ENSCSEP00000020503	ENSCSEP00000002902	Uncharacterized protein.	Lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.544
ENSCSEP00000020503	LOC103389012	ENSCSEP00000020503	ENSCSEP00000023628	Uncharacterized protein.	Apolipoprotein Eb.	0.618
ENSCSEP00000020503	LOC103393985	ENSCSEP00000020503	ENSCSEP00000015525	Uncharacterized protein.	Apolipoprotein Ea.	0.618
ENSCSEP00000020503	npc2	ENSCSEP00000020503	ENSCSEP00000000642	Uncharacterized protein.	Niemann-Pick disease, type C2.	0.559
ENSCSEP00000020503	rps27a	ENSCSEP00000020503	ENSCSEP00000002392	Uncharacterized protein.	Ribosomal protein S27a.	0.400
ENSCSEP00000020503	scarb1	ENSCSEP00000020503	ENSCSEP00000011659	Uncharacterized protein.	Scavenger receptor class B, member 1; Belongs to the CD36 family.	0.406
ENSCSEP00000023105	ENSCSEP00000027680	ENSCSEP00000023105	ENSCSEP00000027680	Low density lipoprotein receptor a.	Myosin regulatory light chain interacting protein a.	0.577
ENSCSEP00000023105	LOC103380907	ENSCSEP00000023105	ENSCSEP00000032638	Low density lipoprotein receptor a.	Apolipoprotein Bb, tandem duplicate 2.	0.545
ENSCSEP00000023105	LOC103389012	ENSCSEP00000023105	ENSCSEP00000023628	Low density lipoprotein receptor a.	Apolipoprotein Eb.	0.470
ENSCSEP00000023105	LOC103394110	ENSCSEP00000023105	ENSCSEP00000018551	Low density lipoprotein receptor a.	Low density lipoprotein receptor adaptor protein 1a.	0.417