96 items (Cynoglossus semilaevis) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103393598	Cytochrome b561. (252 aa)
	LOC103397415	Cytochrome b561 family, member A3a. (312 aa)
	hmox1	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (270 aa)
	ENSCSEP00000023759	Ubiquitin-like domain-containing protein. (92 aa)
	skp1	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (193 aa)
	ENSCSEP00000025064	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (420 aa)
	ENSCSEP00000025082	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (255 aa)
	hmox2	Heme oxygenase 2b. (332 aa)
	UBB	Ubiquitin B. (744 aa)
	cul1	Cullin 1b; Belongs to the cullin family. (766 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (151 aa)
	lcn2	Lipocalin 15; Belongs to the calycin superfamily. Lipocalin family. (182 aa)
	LOC103393644	Mucolipin 1b. (573 aa)
	LOC103393642	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (177 aa)
	slc40a1	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (563 aa)
	atp6v1a	ATPase H+ transporting V1 subunit A. (617 aa)
	LOC103394440	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
	aco1	Aconitase 1, soluble; Belongs to the aconitase/IPM isomerase family. (876 aa)
	LOC103396196	Transferrin receptor 1a. (684 aa)
	ENSCSEP00000028946	ATPase H+ transporting accessory protein 1 like a. (185 aa)
	LOC103381986	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (153 aa)
	ENSCSEP00000029621	Major histocompatibility complex class I ZKA; Belongs to the MHC class I family. (459 aa)
	LOC103395470	Zgc:153704; Belongs to the calycin superfamily. Lipocalin family. (212 aa)
	ATP6V1A	ATPase H+ transporting V1 subunit A. (617 aa)
	cp	Ceruloplasmin; Belongs to the multicopper oxidase family. (1093 aa)
	ENSCSEP00000030311	Zgc:56095. (171 aa)
	LOC103395057	Lens intrinsic membrane protein 2.1. (173 aa)
	slc46a3	Solute carrier family 46 member 3. (498 aa)
	LOC103391409	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
	LOC103386799	TIP120 domain-containing protein. (1205 aa)
	LOC103380812	Feline leukemia virus subgroup C cellular receptor family, member 2b. (492 aa)
	atp6v1g1	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
	LOC103383197	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
	LOC103383323	ATP-binding cassette, sub-family G (WHITE), member 2d. (666 aa)
	LOC103396607	NEDD8 ubiquitin like modifier, like. (67 aa)
	mppe1	Metallophosphoesterase 1. (370 aa)
	ENSCSEP00000028461	ATPase, H+ transporting, lysosomal, V1 subunit B, member a. (205 aa)
	lim2	Lens intrinsic membrane protein 2.4. (173 aa)
	ENSCSEP00000026880	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (326 aa)
	ATP6V0A1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (847 aa)
	LOC103384428	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (375 aa)
	LOC103393222	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (153 aa)
	LOC103398910	Solute carrier family 22 member 31. (379 aa)
	ATP6V1B2	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (517 aa)
	cand1	Cullin-associated and neddylation-dissociated 1. (1211 aa)
	LOC103388364	Ubiquitin-like domain-containing protein. (81 aa)
	atp6v1d	ATPase H+ transporting V1 subunit D. (248 aa)
	LOC103380037	ATPase H+ transporting V1 subunit E1a. (226 aa)
	LOC103383567	Mucolipin 1a. (581 aa)
	ireb2	Iron-responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. (973 aa)
	LOC103399925	Cugbp, Elav-like family member 5a. (477 aa)
	LOC103388282	Cugbp, Elav-like family member 3b. (458 aa)
	LOC103383485	ATP-binding cassette, sub-family G (WHITE), member 2c. (616 aa)
	FLVCR2	Feline leukemia virus subgroup C cellular receptor family member 2. (480 aa)
	LOC103384534	ATPase H+ transporting accessory protein 1a. (530 aa)
	fbxl5	F-box and leucine-rich repeat protein 5. (699 aa)
	LOC103378707	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (181 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	LOC103390475	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (872 aa)
	LOC103384644	ATPase H+ transporting accessory protein 1 like b. (354 aa)
	SLC22A23	Solute carrier family 22 member 23. (637 aa)
	LOC103379949	Zgc:172145. (192 aa)
	LOC103388396	STEAP family member 4. (473 aa)
	ENSCSEP00000007753	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (359 aa)
	ENSCSEP00000007756	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (93 aa)
	LOC103389762	ATP-binding cassette, sub-family G (WHITE), member 2a. (679 aa)
	slc49a4	Solute carrier family 49 member 4. (464 aa)
	flvcr1	Feline leukemia virus subgroup C cellular receptor 1. (528 aa)
	atp6v1f	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
	kxd1	KxDL motif containing 1. (180 aa)
	LOC103382684	ATPase H+ transporting V1 subunit E1b. (237 aa)
	celf4	CUGBP, Elav-like family member 4. (526 aa)
	LOC103378983	Si:dkey-205h23.2. (469 aa)
	slc46a1	Solute carrier family 46 member 1. (492 aa)
	rrp12	Ribosomal RNA processing 12 homolog. (1288 aa)
	LOC103376894	Prostaglandin D2 synthase b, tandem duplicate 1; Belongs to the calycin superfamily. Lipocalin family. (185 aa)
	LOC103394576	Cugbp, Elav-like family member 3a. (453 aa)
	FTH1	Ferritin heavy chain 1. (132 aa)
	ENSCSEP00000012363	Uncharacterized protein. (56 aa)
	atp6v1c1	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (383 aa)
	steap4	STEAP4 metalloreductase. (472 aa)
	SLC22A17	Solute carrier family 22 member 17. (580 aa)
	ENSCSEP00000014305	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (357 aa)
	STEAP3	STEAP family member 3, metalloreductase. (493 aa)
	steap2	STEAP family member 2, metalloreductase. (516 aa)
	hephl1	Hephaestin-like 1b; Belongs to the multicopper oxidase family. (1087 aa)
	LOC103385173	ATPase H+ transporting accessory protein 1b. (451 aa)
	LOC103396290	Uncharacterized protein. (762 aa)
	tcirg1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (809 aa)
	LOC103398525	Consortin, connexin sorting protein b. (374 aa)
	LOC103381661	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (976 aa)
	glrx3	Glutaredoxin 3. (325 aa)
	atp6v0b	ATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (211 aa)
	LOC103398615	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (833 aa)
	SLC49A3	Solute carrier family 49 member 3. (494 aa)
	atp6v1h	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (484 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP6V0A1	ATP6V1A	ENSCSEP00000026933	ENSCSEP00000029825	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	ATPase H+ transporting V1 subunit A.	0.965
ATP6V0A1	ATP6V1B2	ENSCSEP00000026933	ENSCSEP00000027871	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.970
ATP6V0A1	ENSCSEP00000014305	ENSCSEP00000026933	ENSCSEP00000014305	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	0.985
ATP6V0A1	ENSCSEP00000025064	ENSCSEP00000026933	ENSCSEP00000025064	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.702
ATP6V0A1	ENSCSEP00000025082	ENSCSEP00000026933	ENSCSEP00000025082	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.704
ATP6V0A1	ENSCSEP00000026880	ENSCSEP00000026933	ENSCSEP00000026880	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	0.935
ATP6V0A1	ENSCSEP00000028461	ENSCSEP00000026933	ENSCSEP00000028461	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	ATPase, H+ transporting, lysosomal, V1 subunit B, member a.	0.956
ATP6V0A1	ENSCSEP00000028946	ENSCSEP00000026933	ENSCSEP00000028946	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	ATPase H+ transporting accessory protein 1 like a.	0.666
ATP6V0A1	LOC103380037	ENSCSEP00000026933	ENSCSEP00000005314	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	ATPase H+ transporting V1 subunit E1a.	0.962
ATP6V0A1	LOC103381986	ENSCSEP00000026933	ENSCSEP00000029501	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.986
ATP6V0A1	LOC103382684	ENSCSEP00000026933	ENSCSEP00000010728	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	ATPase H+ transporting V1 subunit E1b.	0.962
ATP6V0A1	LOC103383197	ENSCSEP00000026933	ENSCSEP00000032433	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.945
ATP6V0A1	LOC103384428	ENSCSEP00000026933	ENSCSEP00000026955	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.831
ATP6V0A1	LOC103384534	ENSCSEP00000026933	ENSCSEP00000000876	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	ATPase H+ transporting accessory protein 1a.	0.887
ATP6V0A1	LOC103384644	ENSCSEP00000026933	ENSCSEP00000003378	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	ATPase H+ transporting accessory protein 1 like b.	0.666
ATP6V0A1	LOC103385173	ENSCSEP00000026933	ENSCSEP00000015487	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	ATPase H+ transporting accessory protein 1b.	0.887
ATP6V0A1	LOC103390475	ENSCSEP00000026933	ENSCSEP00000002576	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.701
ATP6V0A1	LOC103391409	ENSCSEP00000026933	ENSCSEP00000031123	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.945
ATP6V0A1	LOC103393222	ENSCSEP00000026933	ENSCSEP00000027543	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.986
ATP6V0A1	LOC103394440	ENSCSEP00000026933	ENSCSEP00000028476	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.951