STRINGSTRING
LOC103380525 LOC103380525 LOC103389253 LOC103389253 gss gss LOC103386933 LOC103386933 ENSCSEP00000001955 ENSCSEP00000001955 mat2a mat2a AHCYL1 AHCYL1 Mtr Mtr mtap mtap apip apip LOC103391608 LOC103391608 LOC103381119 LOC103381119 LOC103399977 LOC103399977 ahcyl1 ahcyl1 il4i1 il4i1 srm srm LOC103380166 LOC103380166 got2 got2 LOC112486238 LOC112486238 got1 got1 LOC103380388 LOC103380388 mat2b mat2b LOC103387328 LOC103387328 LOC103380384 LOC103380384 cth cth LOC103385167 LOC103385167 sms sms mdh2 mdh2 MAT1A MAT1A mdh1 mdh1 gclc gclc enoph1 enoph1 mri1 mri1 AHCYL2 AHCYL2 phgdh phgdh ENSCSEP00000019051 ENSCSEP00000019051 LOC103390007 LOC103390007 LOC103380556 LOC103380556 amd1 amd1 SDS SDS cdo1 cdo1 LOC103397629 LOC103397629 Agxt2 Agxt2 gclm gclm ahcy ahcy GOT1 GOT1 LOC103392550 LOC103392550 ENSCSEP00000033616 ENSCSEP00000033616
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103380525Serine dehydratase-like. (328 aa)
LOC103389253Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (584 aa)
gssGlutathione synthetase. (481 aa)
LOC103386933Malate dehydrogenase. (335 aa)
ENSCSEP00000001955Uncharacterized protein. (292 aa)
mat2aS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (396 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (550 aa)
MtrMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1235 aa)
mtapS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (284 aa)
apipMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis. (253 aa)
LOC103391608Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (565 aa)
LOC103381119DNA (cytosine-5-)-methyltransferase 3 alpha a; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (851 aa)
LOC103399977Zgc:172121; Involved in the regulation of homocysteine metabolism. (326 aa)
ahcyl1Adenosylhomocysteinase-like 1; Belongs to the adenosylhomocysteinase family. (555 aa)
il4i1Amine oxidase. (578 aa)
srmSpermidine synthase; Belongs to the spermidine/spermine synthase family. (289 aa)
LOC103380166AdoHcyase_NAD domain-containing protein. (403 aa)
got2Aspartate aminotransferase. (428 aa)
LOC112486238Sulfurtransferase. (296 aa)
got1Aspartate aminotransferase. (410 aa)
LOC103380388DNA (cytosine-5-)-methyltransferase 3 alpha b; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1015 aa)
mat2bMethionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (348 aa)
LOC103387328S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (387 aa)
LOC103380384L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
cthCystathionase (cystathionine gamma-lyase), like. (409 aa)
LOC103385167DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (823 aa)
smsSpermine synthase. (378 aa)
mdh2Malate dehydrogenase. (337 aa)
MAT1AS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (412 aa)
mdh1Malate dehydrogenase. (316 aa)
gclcGlutamate-cysteine ligase, catalytic subunit. (630 aa)
enoph1Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (261 aa)
mri1Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (353 aa)
AHCYL2Adenosylhomocysteinase-like 2. (306 aa)
phgdhD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (529 aa)
ENSCSEP00000019051Aminotran_1_2 domain-containing protein. (269 aa)
LOC103390007Betaine-homocysteine methyltransferase; Involved in the regulation of homocysteine metabolism. (399 aa)
LOC103380556L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (333 aa)
amd1S-adenosylmethionine decarboxylase proenzyme. (335 aa)
SDSSerine dehydratase. (219 aa)
cdo1Cysteine dioxygenase. (201 aa)
LOC103397629Hcy-binding domain-containing protein. (413 aa)
Agxt2Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (474 aa)
gclmGlutamate-cysteine ligase, modifier subunit. (276 aa)
ahcyAdenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. (428 aa)
GOT1Aspartate aminotransferase. (410 aa)
LOC103392550Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (403 aa)
ENSCSEP00000033616DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a. (1400 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.