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mthfd1 mthfd1 tyms tyms atic atic Mtr Mtr ENSCSEP00000004588 ENSCSEP00000004588 aldh1l2 aldh1l2 gart gart mthfr mthfr amt amt shmt1 shmt1 mthfs mthfs mtfmt mtfmt ftcd ftcd LOC103380400 LOC103380400 shmt2 shmt2 LOC103397081 LOC103397081 dhfr dhfr ENSCSEP00000027705 ENSCSEP00000027705 LOC103397730 LOC103397730
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mthfd1Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b. (934 aa)
tymsThymidylate synthetase. (440 aa)
atic5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. (591 aa)
MtrMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1235 aa)
ENSCSEP00000004588Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (879 aa)
aldh1l210-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (901 aa)
gartTrifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1027 aa)
mthfrMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (655 aa)
amtAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (354 aa)
shmt1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (466 aa)
mthfs5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (203 aa)
mtfmtMitochondrial methionyl-tRNA formyltransferase. (369 aa)
ftcdFormimidoyltransferase cyclodeaminase. (540 aa)
LOC103380400Zgc:153031. (196 aa)
shmt2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (501 aa)
LOC103397081Uncharacterized protein. (338 aa)
dhfrDihydrofolate reductase. (189 aa)
ENSCSEP0000002770510-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (898 aa)
LOC103397730Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. (411 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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