(9 nodes) Terpenoid backbone biosynthesis network (Dichelobacter nodosus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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Predicted Interactions

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Your Input:
	DNO_0489	Identified by match to protein family HMM PF00288. (303 aa)
	mvaD	Diphosphomevalonate decarboxylase; Identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01240. (328 aa)
	ispA	Geranyltranstransferase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. (280 aa)
	uppS	Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. (247 aa)
	DNO_0797	Hydroxymethylglutaryl-coenzyme A reductase; Identified by match to protein family HMM PF00368. (350 aa)
	fni	Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (344 aa)
	DNO_0799	hydroxymethylglutaryl-CoA synthase; Identified by match to protein family HMM PF01154; match to protein family HMM PF08540; match to protein family HMM TIGR01835. (384 aa)
	DNO_0800	Identified by match to protein family HMM PF00288. (352 aa)
	DNO_0945	Polyprenyl synthase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. (348 aa)

Your Current Organism:

Dichelobacter nodosus

NCBI taxonomy Id: 246195
Other names: D. nodosus VCS1703A, Dichelobacter nodosus VCS1703A, Dichelobacter nodosus str. VCS1703A

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DNO_0489	DNO_0797	DNO_0489	DNO_0797	Identified by match to protein family HMM PF00288.	Hydroxymethylglutaryl-coenzyme A reductase; Identified by match to protein family HMM PF00368.	0.981
DNO_0489	DNO_0799	DNO_0489	DNO_0799	Identified by match to protein family HMM PF00288.	hydroxymethylglutaryl-CoA synthase; Identified by match to protein family HMM PF01154; match to protein family HMM PF08540; match to protein family HMM TIGR01835.	0.826
DNO_0489	DNO_0800	DNO_0489	DNO_0800	Identified by match to protein family HMM PF00288.	Identified by match to protein family HMM PF00288.	0.978
DNO_0489	fni	DNO_0489	DNO_0798	Identified by match to protein family HMM PF00288.	Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).	0.789
DNO_0489	mvaD	DNO_0489	DNO_0504	Identified by match to protein family HMM PF00288.	Diphosphomevalonate decarboxylase; Identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01240.	0.909
DNO_0797	DNO_0489	DNO_0797	DNO_0489	Hydroxymethylglutaryl-coenzyme A reductase; Identified by match to protein family HMM PF00368.	Identified by match to protein family HMM PF00288.	0.981
DNO_0797	DNO_0799	DNO_0797	DNO_0799	Hydroxymethylglutaryl-coenzyme A reductase; Identified by match to protein family HMM PF00368.	hydroxymethylglutaryl-CoA synthase; Identified by match to protein family HMM PF01154; match to protein family HMM PF08540; match to protein family HMM TIGR01835.	0.999
DNO_0797	DNO_0800	DNO_0797	DNO_0800	Hydroxymethylglutaryl-coenzyme A reductase; Identified by match to protein family HMM PF00368.	Identified by match to protein family HMM PF00288.	0.995
DNO_0797	fni	DNO_0797	DNO_0798	Hydroxymethylglutaryl-coenzyme A reductase; Identified by match to protein family HMM PF00368.	Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).	0.906
DNO_0797	mvaD	DNO_0797	DNO_0504	Hydroxymethylglutaryl-coenzyme A reductase; Identified by match to protein family HMM PF00368.	Diphosphomevalonate decarboxylase; Identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01240.	0.837
DNO_0799	DNO_0489	DNO_0799	DNO_0489	hydroxymethylglutaryl-CoA synthase; Identified by match to protein family HMM PF01154; match to protein family HMM PF08540; match to protein family HMM TIGR01835.	Identified by match to protein family HMM PF00288.	0.826
DNO_0799	DNO_0797	DNO_0799	DNO_0797	hydroxymethylglutaryl-CoA synthase; Identified by match to protein family HMM PF01154; match to protein family HMM PF08540; match to protein family HMM TIGR01835.	Hydroxymethylglutaryl-coenzyme A reductase; Identified by match to protein family HMM PF00368.	0.999
DNO_0799	DNO_0800	DNO_0799	DNO_0800	hydroxymethylglutaryl-CoA synthase; Identified by match to protein family HMM PF01154; match to protein family HMM PF08540; match to protein family HMM TIGR01835.	Identified by match to protein family HMM PF00288.	0.985
DNO_0799	fni	DNO_0799	DNO_0798	hydroxymethylglutaryl-CoA synthase; Identified by match to protein family HMM PF01154; match to protein family HMM PF08540; match to protein family HMM TIGR01835.	Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).	0.947
DNO_0799	mvaD	DNO_0799	DNO_0504	hydroxymethylglutaryl-CoA synthase; Identified by match to protein family HMM PF01154; match to protein family HMM PF08540; match to protein family HMM TIGR01835.	Diphosphomevalonate decarboxylase; Identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01240.	0.914
DNO_0800	DNO_0489	DNO_0800	DNO_0489	Identified by match to protein family HMM PF00288.	Identified by match to protein family HMM PF00288.	0.978
DNO_0800	DNO_0797	DNO_0800	DNO_0797	Identified by match to protein family HMM PF00288.	Hydroxymethylglutaryl-coenzyme A reductase; Identified by match to protein family HMM PF00368.	0.995
DNO_0800	DNO_0799	DNO_0800	DNO_0799	Identified by match to protein family HMM PF00288.	hydroxymethylglutaryl-CoA synthase; Identified by match to protein family HMM PF01154; match to protein family HMM PF08540; match to protein family HMM TIGR01835.	0.985
DNO_0800	fni	DNO_0800	DNO_0798	Identified by match to protein family HMM PF00288.	Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).	0.940
DNO_0800	mvaD	DNO_0800	DNO_0504	Identified by match to protein family HMM PF00288.	Diphosphomevalonate decarboxylase; Identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01240.	0.907