STRINGSTRING
murB murB alr alr ddl ddl ABK76053.1 ABK76053.1 ABK76142.1 ABK76142.1 sepF sepF ABK72274.1 ABK72274.1 ABK69811.1 ABK69811.1 ftsZ ftsZ ABK73546.1 ABK73546.1 ftsQ ftsQ murC murC murG murG ftsW ftsW murD murD mraY mraY murF murF murE murE pbpB pbpB ABK72118.1 ABK72118.1 mraW mraW mraZ mraZ ABK76060.1 ABK76060.1 murA murA ABK70790.1 ABK70790.1 ABK72238.1 ABK72238.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (363 aa)
alrAlanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (389 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation. (373 aa)
ABK76053.1Penicillin-binding protein, putative; Identified by match to protein family HMM PF00905; match to protein family HMM PF05223. (606 aa)
ABK76142.1Possible conserved transmembrane protein. (96 aa)
sepFConserved hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (214 aa)
ABK72274.1Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. (291 aa)
ABK69811.1Conserved hypothetical protein; Identified by match to protein family HMM PF02578; match to protein family HMM TIGR00726; Belongs to the multicopper oxidase YfiH/RL5 family. (237 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (385 aa)
ABK73546.1Hypothetical protein; Identified by Glimmer2; putative. (42 aa)
ftsQPutative Cell division protein FtsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. (333 aa)
murCUDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (482 aa)
murGUndecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (385 aa)
ftsWCell division protein FtsW; Identified by match to protein family HMM PF01098; match to protein family HMM TIGR02614; Belongs to the SEDS family. (568 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (493 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (359 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (509 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (520 aa)
pbpBPenicillin binding protein transpeptidase domain protein; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717; Belongs to the transpeptidase family. (648 aa)
ABK72118.1Conserved hypothetical protein. (380 aa)
mraWS-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (326 aa)
mraZMraZ protein; Identified by match to protein family HMM PF02381; match to protein family HMM TIGR00242; Belongs to the MraZ family. (143 aa)
ABK76060.1Penicillin binding protein transpeptidase domain protein; Identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM PF03793. (803 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (418 aa)
ABK70790.1Transglycosylase; Identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM PF03793. (788 aa)
ABK72238.1Penicillin-binding protein, transpeptidase; Identified by match to protein family HMM PF00905; match to protein family HMM PF05223. (592 aa)
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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