STRINGSTRING
ABK73576.1 ABK73576.1 ABK70024.1 ABK70024.1 ABK70350.1 ABK70350.1 ABK71342.1 ABK71342.1 ABK74307.1 ABK74307.1 ABK73660.1 ABK73660.1 ABK75680.1 ABK75680.1 ABK75405.1 ABK75405.1 ABK74414.1 ABK74414.1 ABK75524.1 ABK75524.1 ABK76088.1 ABK76088.1 ABK74294.1 ABK74294.1 ABK70714.1 ABK70714.1 ABK72663.1 ABK72663.1 ABK75049.1 ABK75049.1 ABK73820.1 ABK73820.1 ABK73736.1 ABK73736.1 ABK74247.1 ABK74247.1 ABK73922.1 ABK73922.1 ABK69642.1 ABK69642.1 ABK72258.1 ABK72258.1 ABK73406.1 ABK73406.1 ABK74229.1 ABK74229.1 ABK71081.1 ABK71081.1 ABK73458.1 ABK73458.1 ABK70910.1 ABK70910.1 ABK70182.1 ABK70182.1 ABK74703.1 ABK74703.1 ABK70678.1 ABK70678.1 ABK73400.1 ABK73400.1 ABK70445.1 ABK70445.1 ABK71069.1 ABK71069.1 ABK76239.1 ABK76239.1 ABK70939.1 ABK70939.1 ABK70754.1 ABK70754.1 ABK71336.1 ABK71336.1 ABK75925.1 ABK75925.1 ABK71318.1 ABK71318.1 ABK75075.1 ABK75075.1 ABK73993.1 ABK73993.1 ABK72504.1 ABK72504.1 ABK74699.1 ABK74699.1 mimA mimA mimD mimD ABK70393.1 ABK70393.1 ABK71963.1 ABK71963.1 ABK69576.1 ABK69576.1 ABK75568.1 ABK75568.1 ABK70900.1 ABK70900.1 ABK73724.1 ABK73724.1 ABK72024.1 ABK72024.1 ABK72971.1 ABK72971.1 ABK71152.1 ABK71152.1 ABK75646.1 ABK75646.1 ABK74980.1 ABK74980.1 ABK75492.1 ABK75492.1 ABK71945.1 ABK71945.1 ABK71459.1 ABK71459.1 ABK73097.1 ABK73097.1 ABK73356.1 ABK73356.1 ABK74993.1 ABK74993.1 ssuD ssuD ssuD-2 ssuD-2 ABK70591.1 ABK70591.1 ABK71859.1 ABK71859.1 ABK72155.1 ABK72155.1 ABK71230.1 ABK71230.1 ABK71452.1 ABK71452.1 ABK69720.1 ABK69720.1 ABK70888.1 ABK70888.1 ABK71655.1 ABK71655.1 ABK72152.1 ABK72152.1 ABK74355.1 ABK74355.1 ABK69974.1 ABK69974.1 ABK75146.1 ABK75146.1 ABK72784.1 ABK72784.1 ABK70976.1 ABK70976.1 ABK72115.1 ABK72115.1 ABK73619.1 ABK73619.1 ABK72493.1 ABK72493.1 ABK69647.1 ABK69647.1 ssuD-4 ssuD-4 ABK76152.1 ABK76152.1 ssuD-5 ssuD-5 ABK72738.1 ABK72738.1 ABK72567.1 ABK72567.1 ABK75942.1 ABK75942.1 ABK71361.1 ABK71361.1 ABK71803.1 ABK71803.1 ABK73860.1 ABK73860.1 ABK75988.1 ABK75988.1 ABK76074.1 ABK76074.1 ABK70003.1 ABK70003.1 ABK71667.1 ABK71667.1 ssuD-6 ssuD-6 ssuD-7 ssuD-7 ABK73667.1 ABK73667.1 ABK72736.1 ABK72736.1 ABK70288.1 ABK70288.1 ABK73430.1 ABK73430.1 ABK75448.1 ABK75448.1 ABK73604.1 ABK73604.1 ABK69528.1 ABK69528.1 ABK72320.1 ABK72320.1 mhpA mhpA ABK75246.1 ABK75246.1 ABK74324.1 ABK74324.1 ABK69678.1 ABK69678.1 ABK72693.1 ABK72693.1 ABK73801.1 ABK73801.1 ABK70209.1 ABK70209.1 ABK76019.1 ABK76019.1 ABK70246.1 ABK70246.1 ABK74809.1 ABK74809.1 ABK75456.1 ABK75456.1 ABK73207.1 ABK73207.1 ABK71599.1 ABK71599.1 ABK75192.1 ABK75192.1 ABK72501.1 ABK72501.1 cyp142 cyp142 kshA kshA cyp125 cyp125 ABK69721.1 ABK69721.1 ABK73596.1 ABK73596.1 ABK71346.1 ABK71346.1 kshB kshB ABK70526.1 ABK70526.1 ABK72340.1 ABK72340.1 egtB egtB ABK70618.1 ABK70618.1 ABK76191.1 ABK76191.1 ethA ethA ABK70280.1 ABK70280.1 ABK71893.1 ABK71893.1 ABK75575.1 ABK75575.1 ABK70871.1 ABK70871.1 ABK71257.1 ABK71257.1 ABK76236.1 ABK76236.1 ABK70982.1 ABK70982.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABK73576.1L-ornithine 5-monooxygenase. (440 aa)
ABK70024.1C-5 sterol desaturase. (304 aa)
ABK70350.1Steroid monooxygenase; Identified by match to protein family HMM PF01266; match to protein family HMM PF07992. (546 aa)
ABK71342.1Rieske [2Fe-2S] domain protein; Identified by match to protein family HMM PF00355. (421 aa)
ABK74307.1Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970. (358 aa)
ABK73660.1Rieske [2Fe-2S] domain protein; Identified by match to protein family HMM PF00355. (421 aa)
ABK75680.12-nitropropane dioxygenase, NPD; Identified by match to protein family HMM PF03060. (311 aa)
ABK75405.1Conserved hypothetical protein. (346 aa)
ABK74414.1Flavoprotein involved in K+ transport; Identified by match to protein family HMM PF07992. (423 aa)
ABK75524.1Conserved hypothetical protein. (98 aa)
ABK76088.1Rieske 2Fe-2S domain protein; Identified by match to protein family HMM PF00355. (394 aa)
ABK74294.1Putative cytochrome P450 144; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (405 aa)
ABK70714.1P450 heme-thiolate protein; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (422 aa)
ABK72663.1Flavohemoprotein; Identified by match to protein family HMM PF00042; match to protein family HMM PF00175; match to protein family HMM PF00970; Belongs to the globin family. (379 aa)
ABK75049.1Rieske [2Fe-2S] domain protein; Identified by match to protein family HMM PF00355. (359 aa)
ABK73820.1Cytochrome P450 FAS1; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (401 aa)
ABK73736.1Flavin-binding monooxygenase; Identified by match to protein family HMM PF01266; match to protein family HMM PF07992. (494 aa)
ABK74247.1Cytochrome P450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (455 aa)
ABK73922.1Oxygenase. (105 aa)
ABK69642.1Cytochrome P450; Identified by match to protein family HMM PF00067. (484 aa)
ABK72258.12-nitropropane dioxygenase, NPD; Identified by match to protein family HMM PF03060. (375 aa)
ABK73406.1Cytochrome p450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (494 aa)
ABK74229.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (292 aa)
ABK71081.1Monooxygenase. (499 aa)
ABK73458.1Nitrilotriacetate monooxygenase component A. (448 aa)
ABK70910.1Cytochrome P450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (479 aa)
ABK70182.1Cytochrome P450 monooxygenase; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (437 aa)
ABK74703.1Cytochrome P450-terp; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (416 aa)
ABK70678.1Cytochrome P450-terp; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (431 aa)
ABK73400.1Rieske [2Fe-2S] domain protein; Identified by match to protein family HMM PF00355. (116 aa)
ABK70445.1Ferredoxin; Identified by match to protein family HMM PF00355. (117 aa)
ABK71069.1Oxygenase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494. (501 aa)
ABK76239.1FAD dependent oxidoreductase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494. (514 aa)
ABK70939.1Oxidoreductase, 2-nitropropane dioxygenase family protein; Identified by match to protein family HMM PF03060. (289 aa)
ABK70754.1Flavin-containing monooxygenase FMO. (421 aa)
ABK71336.1Putative ammonia monooxygenase superfamily protein; Identified by match to protein family HMM PF05145; match to protein family HMM TIGR03082. (369 aa)
ABK75925.1Pentachlorophenol 4-monooxygenase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494. (382 aa)
ABK71318.1Putative monooxygenase. (293 aa)
ABK75075.1Cytochrome P450 monooxygenase. (457 aa)
ABK73993.1Secreted protein. (469 aa)
ABK72504.1Alkane 1-monooxygenase; Identified by match to protein family HMM PF00487. (410 aa)
ABK74699.1Benzoate 1,2-dioxygenase alpha subunit; Identified by match to protein family HMM PF00355; match to protein family HMM PF00848. (454 aa)
mimAPropane monooxygenase hydroxylase large subunit; Component of the propane 2-monooxygenase multicomponent enzyme system which is involved in the degradation of propane via the O2-dependent hydroxylation of propane. Also involved in the degradation of acetone via the O2-dependent hydroxylation of acetone. Also able to catalyze the oxidation of phenol, methylethylketone (2-butanone), 1-propanol and 2-propanol. (542 aa)
mimDPropane monooxygenase coupling protein; Effector component of the propane 2-monooxygenase multicomponent enzyme system which is involved in the degradation of propane via the O2-dependent hydroxylation of propane. (114 aa)
ABK70393.1Identified by match to protein family HMM PF01266. (519 aa)
ABK71963.1Monoxygenase; Identified by match to protein family HMM PF00296. (454 aa)
ABK69576.1Nitrilotriacetate monooxygenase component A. (458 aa)
ABK75568.1Dimethylaniline monooxygenase [N-oxide-forming] 5; Identified by match to protein family HMM PF00743. (454 aa)
ABK70900.1Cytochrome P450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (402 aa)
ABK73724.1Rieske [2Fe-2S] domain protein; Identified by match to protein family HMM PF00355. (338 aa)
ABK72024.1Flavin-type hydroxylase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494. (494 aa)
ABK72971.1Cytochrome P450-terp; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (411 aa)
ABK71152.1Cytochrome p450; Identified by match to protein family HMM PF00067. (494 aa)
ABK75646.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (292 aa)
ABK74980.1Monooxygenase. (499 aa)
ABK75492.1Monooxygenase, FAD-binding; Identified by match to protein family HMM PF01494. (535 aa)
ABK71945.1NikQ protein; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (418 aa)
ABK71459.1Cytochrome P450 superfamily protein; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (412 aa)
ABK73097.1Probable monooxygenase. (504 aa)
ABK73356.1C-5 sterol desaturase. (290 aa)
ABK74993.1Putative monooxygenase. (481 aa)
ssuDNitrilotriacetate monooxygenase component A. (431 aa)
ssuD-2Nitrilotriacetate monooxygenase component A. (451 aa)
ABK70591.1Oxygenase KshA; Identified by match to protein family HMM PF00355. (386 aa)
ABK71859.1Cyclohexanone monooxygenase. (640 aa)
ABK72155.1Oxidoreductase, NAD/FAD-binding; Identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970. (351 aa)
ABK71230.1Steroid monooxygenase; Identified by match to protein family HMM PF01266. (540 aa)
ABK71452.1MmcI protein. (130 aa)
ABK69720.1Conserved hypothetical protein. (274 aa)
ABK70888.1Steroid monooxygenase; Identified by match to protein family HMM PF01266. (548 aa)
ABK71655.1Cytochrome P450 107B1; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (421 aa)
ABK72152.1Oxidoreductase, 2-nitropropane dioxygenase family protein; Identified by match to protein family HMM PF03060. (376 aa)
ABK74355.1Linalool 8-monooxygenase; Belongs to the cytochrome P450 family. (430 aa)
ABK69974.1Linalool 8-monooxygenase; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (425 aa)
ABK75146.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (309 aa)
ABK72784.1C-5 sterol desaturase. (307 aa)
ABK70976.1Cytochrome P450 monooxygenase; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (407 aa)
ABK72115.14-hydroxyacetophenone monooxygenase. (485 aa)
ABK73619.1Monoxygenase. (448 aa)
ABK72493.1Putative monooxygenase. (471 aa)
ABK69647.1Nitrilotriacetate monooxygenase component A. (427 aa)
ssuD-4Nitrilotriacetate monooxygenase component A. (444 aa)
ABK76152.1Putative monooxygenase. (305 aa)
ssuD-5Nitrilotriacetate monooxygenase component A. (411 aa)
ABK72738.1Cytochrome P450. (152 aa)
ABK72567.1Cytochrome P450 hydroxylase; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (385 aa)
ABK75942.1Ubiquinol-cytochrome c reductase iron-sulfur subunit; Identified by match to protein family HMM PF00355. (408 aa)
ABK71361.1Conserved hypothetical protein; Identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM TIGR01777. (302 aa)
ABK71803.1Putative monooxygenase. (460 aa)
ABK73860.1Capreomycidine hydroxylase; Identified by match to protein family HMM PF00355. (364 aa)
ABK75988.1Monooxygenase, NtaA/SnaA/SoxA family protein. (456 aa)
ABK76074.1Probable monooxygenase. (570 aa)
ABK70003.1MbtG protein. (435 aa)
ABK71667.1Monoxygenase. (460 aa)
ssuD-6Nitrilotriacetate monooxygenase component A; Identified by match to protein family HMM PF00296. (434 aa)
ssuD-7Nitrilotriacetate monooxygenase component A. (445 aa)
ABK73667.1Putative cytochrome P450 126; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (419 aa)
ABK72736.1Cytochrome p450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (437 aa)
ABK70288.1Cytochrome P450 superfamily protein; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (453 aa)
ABK73430.1Putative cytochrome P450 123; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (400 aa)
ABK75448.1Cytochrome p450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (428 aa)
ABK73604.1Cytochrome P450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (396 aa)
ABK69528.1Rieske [2Fe-2S] domain protein; Identified by match to protein family HMM PF00355. (447 aa)
ABK72320.1Cytochrome P450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (410 aa)
mhpA3-(3-hydroxy-phenyl)propionate hydroxylase; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI). (563 aa)
ABK75246.1Cytochrome P450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (400 aa)
ABK74324.1Oxidoreductase; Identified by match to protein family HMM PF03060. (340 aa)
ABK69678.1Conserved hypothetical protein; Belongs to the UPF0311 family. (160 aa)
ABK72693.1Putative cytochrome P450 123; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (406 aa)
ABK73801.12-Nitropropane dioxygenase; Identified by match to protein family HMM PF03060. (337 aa)
ABK70209.1Hypothetical protein; Identified by Glimmer2; putative. (505 aa)
ABK76019.1Cyclododecanone monooxygenase; Identified by match to protein family HMM PF01266. (612 aa)
ABK70246.1Rieske [2Fe-2S] domain protein; Identified by match to protein family HMM PF00355. (462 aa)
ABK74809.1Putative monooxygenase. (469 aa)
ABK75456.1NikQ protein; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (401 aa)
ABK73207.1Cytochrome P450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (411 aa)
ABK71599.1Cytochrome P450 109; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (400 aa)
ABK75192.1Cytochrome P450 51; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (451 aa)
ABK72501.1Dioxygenase; Identified by match to protein family HMM PF03060. (373 aa)
cyp142P450 heme-thiolate protein; Involved in the utilization of cholesterol as the sole carbon and energy source by degrading the side chain. Primarily catalyzes the sequential oxidation of the terminal methyl of cholest-4-en-3-one into (25R)-26-hydroxycholest-4-en-3-one (alcohol), (25R)-26-oxocholest-4-en- 3-one (aldehyde), to finally yield the carboxylic acid (25R)-3- oxocholest-4-en-26-oate. Also able to sequentially oxidize cholesterol itself, not only cholest-4-en-3-one. (401 aa)
kshARieske [2Fe-2S] domain protein; Involved in the degradation of cholesterol. Catalyzes the introduction of a 9a-hydroxyl moiety into 1,4-androstadiene-3,17-dione (ADD) to yield the 9alpha-hydroxy-1,4-androstadiene-3,17-dione (9OHADD) intermediate which spontaneously form 3-hydroxy-9,10-seconandrost- 1,3,5(10)-triene-9,17-dione (HSA) via the meta-cleavage of ring B with concomitant aromatization of ring A. (383 aa)
cyp125P450 heme-thiolate protein; Involved in the utilization of cholesterol as the sole carbon and energy source by degrading the side chain. Primarily catalyzes the sequential oxidation of the terminal methyl of cholest-4-en-3-one into (25S)-26-hydroxycholest-4-en-3-one (alcohol), (25S)-26-oxocholest-4-en- 3-one (aldehyde), to finally yield the carboxylic acid (25S)-3- oxocholest-4-en-26-oate. Also able to sequentially oxidize cholesterol itself, not only cholest-4-en-3-one. (427 aa)
ABK69721.1Oxidoreductase, 2-nitropropane dioxygenase family protein; Identified by similarity to GB:AAF98273.1; match to protein family HMM PF03060. (358 aa)
ABK73596.1Cytochrome p450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (429 aa)
ABK71346.1Pigment production hydroxylase; Identified by match to protein family HMM PF08028. (396 aa)
kshBOxidoreductase, electron transfer component; Involved in the degradation of cholesterol. Catalyzes the introduction of a 9a-hydroxyl moiety into 1,4-androstadiene-3,17-dione (ADD) to yield the 9alpha-hydroxy-1,4-androstadiene-3,17-dione (9OHADD) intermediate which spontaneously form 3-hydroxy-9,10-seconandrost- 1,3,5(10)-triene-9,17-dione (HSA) via the meta-cleavage of ring B with concomitant aromatization of ring A. (353 aa)
ABK70526.1Antibiotic biosynthesis monooxygenase domain protein; Identified by match to protein family HMM PF03992. (105 aa)
ABK72340.1Limonene 1,2-monooxygenase; Identified by match to protein family HMM PF00296. (395 aa)
egtBConserved hypothetical protein; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. Cannot use the alternative thiols cysteine, N- acetylcysteine, or glutathione instead of gamma-glutamylcysteine as substrates, and histidine is a poor sulfur acceptor substrate compared to hercynine; Belongs to the EgtB family. (428 aa)
ABK70618.1Cytochrome P450 107B1; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (414 aa)
ABK76191.1Identified by match to protein family HMM PF00355. (518 aa)
ethAMonooxygenase, flavin-binding family protein; Monooxygenase able to convert a wide range of ketones to the corresponding esters or lactones via a Baeyer-Villiger oxidation reaction. Can act on long-chain aliphatic ketones (2-hexanone to 2- dodecanone) and on aromatic ketones (phenylacetone and benzylacetone). Is also able to catalyze enantioselective sulfoxidation of methyl-p- tolylsulfide. In vivo, likely functions as a BVMO, but the exact nature of the physiological substrate(s) remains to be established. (492 aa)
ABK70280.1Putative cytochrome P450 135B1; Identified by match to protein family HMM PF00067. (447 aa)
ABK71893.1Cytochrome P450 monooxygenase; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (396 aa)
ABK75575.1Nitrilotriacetate monooxygenase component A. (453 aa)
ABK70871.1Cytochrome P450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (400 aa)
ABK71257.1Dibenzothiophene desulfurization enzyme A. (437 aa)
ABK76236.1MmcI protein. (274 aa)
ABK70982.1MmcI protein. (257 aa)
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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