13 items (Mycolicibacterium smegmatis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ABK70809.1	Glyoxylate reductase; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (322 aa)
	ABK74733.1	HAD-superfamily protein subfamily protein IB hydrolase, TIGR01490; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490. (296 aa)
	serB	Phosphoserine phosphatase; Identified by match to protein family HMM PF00702; match to protein family HMM PF01842; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488. (413 aa)
	ABK69677.1	Molybdopterin biosynthesis protein MoeB; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237. (396 aa)
	serB-2	Phosphoserine phosphatase; Identified by match to protein family HMM PF00702; match to protein family HMM PF01842; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488. (413 aa)
	serA	D-3-phosphoglycerate dehydrogenase; Identified by match to protein family HMM PF00389; match to protein family HMM PF01842; match to protein family HMM PF02826; match to protein family HMM TIGR01327; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (528 aa)
	ABK73577.1	HAD-superfamily protein subfamily protein IB hydrolase; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490. (223 aa)
	cysM	Cysteine synthase B; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136. (323 aa)
	glyA	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (490 aa)
	serC	Phosphoserine aminotransferase, putative; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (370 aa)
	cysE	Serine O-acetyltransferase. (172 aa)
	ABK72506.1	Phosphoglycerate dehydrogenase; Identified by match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (334 aa)
	ABK71449.1	Morphological differentiation-associated protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490. (293 aa)

Your Current Organism:

Mycolicibacterium smegmatis

NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABK69677.1	ABK70809.1	MSMEG_1937	MSMEG_0604	Molybdopterin biosynthesis protein MoeB; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237.	Glyoxylate reductase; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.410
ABK69677.1	ABK72506.1	MSMEG_1937	MSMEG_6115	Molybdopterin biosynthesis protein MoeB; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237.	Phosphoglycerate dehydrogenase; Identified by match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.408
ABK69677.1	cysM	MSMEG_1937	MSMEG_4905	Molybdopterin biosynthesis protein MoeB; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237.	Cysteine synthase B; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136.	0.652
ABK69677.1	serA	MSMEG_1937	MSMEG_2378	Molybdopterin biosynthesis protein MoeB; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237.	D-3-phosphoglycerate dehydrogenase; Identified by match to protein family HMM PF00389; match to protein family HMM PF01842; match to protein family HMM PF02826; match to protein family HMM TIGR01327; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.414
ABK70809.1	ABK69677.1	MSMEG_0604	MSMEG_1937	Glyoxylate reductase; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Molybdopterin biosynthesis protein MoeB; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237.	0.410
ABK70809.1	ABK74733.1	MSMEG_0604	MSMEG_0949	Glyoxylate reductase; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	HAD-superfamily protein subfamily protein IB hydrolase, TIGR01490; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490.	0.438
ABK70809.1	glyA	MSMEG_0604	MSMEG_5249	Glyoxylate reductase; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.595
ABK70809.1	serC	MSMEG_0604	MSMEG_5684	Glyoxylate reductase; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Phosphoserine aminotransferase, putative; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.	0.740
ABK71449.1	serC	MSMEG_6173	MSMEG_5684	Morphological differentiation-associated protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490.	Phosphoserine aminotransferase, putative; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.	0.635
ABK72506.1	ABK69677.1	MSMEG_6115	MSMEG_1937	Phosphoglycerate dehydrogenase; Identified by match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Molybdopterin biosynthesis protein MoeB; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237.	0.408
ABK72506.1	ABK74733.1	MSMEG_6115	MSMEG_0949	Phosphoglycerate dehydrogenase; Identified by match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	HAD-superfamily protein subfamily protein IB hydrolase, TIGR01490; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490.	0.447
ABK72506.1	glyA	MSMEG_6115	MSMEG_5249	Phosphoglycerate dehydrogenase; Identified by match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.594
ABK72506.1	serC	MSMEG_6115	MSMEG_5684	Phosphoglycerate dehydrogenase; Identified by match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Phosphoserine aminotransferase, putative; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.	0.736
ABK73577.1	serC	MSMEG_3517	MSMEG_5684	HAD-superfamily protein subfamily protein IB hydrolase; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490.	Phosphoserine aminotransferase, putative; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.	0.554
ABK74733.1	ABK70809.1	MSMEG_0949	MSMEG_0604	HAD-superfamily protein subfamily protein IB hydrolase, TIGR01490; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490.	Glyoxylate reductase; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.438
ABK74733.1	ABK72506.1	MSMEG_0949	MSMEG_6115	HAD-superfamily protein subfamily protein IB hydrolase, TIGR01490; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490.	Phosphoglycerate dehydrogenase; Identified by match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.447
ABK74733.1	serA	MSMEG_0949	MSMEG_2378	HAD-superfamily protein subfamily protein IB hydrolase, TIGR01490; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490.	D-3-phosphoglycerate dehydrogenase; Identified by match to protein family HMM PF00389; match to protein family HMM PF01842; match to protein family HMM PF02826; match to protein family HMM TIGR01327; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.770
ABK74733.1	serB	MSMEG_0949	MSMEG_1041	HAD-superfamily protein subfamily protein IB hydrolase, TIGR01490; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490.	Phosphoserine phosphatase; Identified by match to protein family HMM PF00702; match to protein family HMM PF01842; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488.	0.419
ABK74733.1	serB-2	MSMEG_0949	MSMEG_2321	HAD-superfamily protein subfamily protein IB hydrolase, TIGR01490; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490.	Phosphoserine phosphatase; Identified by match to protein family HMM PF00702; match to protein family HMM PF01842; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488.	0.419
ABK74733.1	serC	MSMEG_0949	MSMEG_5684	HAD-superfamily protein subfamily protein IB hydrolase, TIGR01490; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490.	Phosphoserine aminotransferase, putative; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.	0.776