node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK71532.1 | ABK75112.1 | MSMEG_5457 | MSMEG_6704 | Shikimate 5-dehydrogenase; Identified by match to protein family HMM PF01488. | Shikimate 5-dehydrogenase; Identified by match to protein family HMM PF01488. | 0.961 |
ABK71532.1 | aroA | MSMEG_5457 | MSMEG_1890 | Shikimate 5-dehydrogenase; Identified by match to protein family HMM PF01488. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.665 |
ABK71532.1 | aroB | MSMEG_5457 | MSMEG_3033 | Shikimate 5-dehydrogenase; Identified by match to protein family HMM PF01488. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.577 |
ABK71532.1 | aroC | MSMEG_5457 | MSMEG_3030 | Shikimate 5-dehydrogenase; Identified by match to protein family HMM PF01488. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.767 |
ABK71532.1 | aroK-2 | MSMEG_5457 | MSMEG_3031 | Shikimate 5-dehydrogenase; Identified by match to protein family HMM PF01488. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.950 |
ABK71532.1 | aroQ | MSMEG_5457 | MSMEG_1922 | Shikimate 5-dehydrogenase; Identified by match to protein family HMM PF01488. | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.930 |
ABK71532.1 | aroQ-2 | MSMEG_5457 | MSMEG_2532 | Shikimate 5-dehydrogenase; Identified by match to protein family HMM PF01488. | Dehydroquinase dehydratase, type II; Identified by match to protein family HMM PF01220. | 0.930 |
ABK72386.1 | aroA | MSMEG_2799 | MSMEG_1890 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.475 |
ABK72386.1 | aroB | MSMEG_2799 | MSMEG_3033 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.981 |
ABK72386.1 | aroC | MSMEG_2799 | MSMEG_3030 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.514 |
ABK72386.1 | aroG | MSMEG_2799 | MSMEG_4244 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 3-deoxy-7-phosphoheptulonate synthase; Catalyzes an aldol-like condensation reaction between phosphoenolpyruvate (PEP) and D-erythrose 4-phosphate (E4P) to generate 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAH7P) and inorganic phosphate. | 0.918 |
ABK72386.1 | aroK-2 | MSMEG_2799 | MSMEG_3031 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.727 |
ABK75112.1 | ABK71532.1 | MSMEG_6704 | MSMEG_5457 | Shikimate 5-dehydrogenase; Identified by match to protein family HMM PF01488. | Shikimate 5-dehydrogenase; Identified by match to protein family HMM PF01488. | 0.961 |
ABK75112.1 | aroA | MSMEG_6704 | MSMEG_1890 | Shikimate 5-dehydrogenase; Identified by match to protein family HMM PF01488. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.652 |
ABK75112.1 | aroB | MSMEG_6704 | MSMEG_3033 | Shikimate 5-dehydrogenase; Identified by match to protein family HMM PF01488. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.704 |
ABK75112.1 | aroC | MSMEG_6704 | MSMEG_3030 | Shikimate 5-dehydrogenase; Identified by match to protein family HMM PF01488. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.824 |
ABK75112.1 | aroK-2 | MSMEG_6704 | MSMEG_3031 | Shikimate 5-dehydrogenase; Identified by match to protein family HMM PF01488. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.961 |
ABK75112.1 | aroQ | MSMEG_6704 | MSMEG_1922 | Shikimate 5-dehydrogenase; Identified by match to protein family HMM PF01488. | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.941 |
ABK75112.1 | aroQ-2 | MSMEG_6704 | MSMEG_2532 | Shikimate 5-dehydrogenase; Identified by match to protein family HMM PF01488. | Dehydroquinase dehydratase, type II; Identified by match to protein family HMM PF01220. | 0.942 |
aroA | ABK71532.1 | MSMEG_1890 | MSMEG_5457 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate 5-dehydrogenase; Identified by match to protein family HMM PF01488. | 0.665 |