STRINGSTRING
ABK70836.1 ABK70836.1 truA truA ABK76013.1 ABK76013.1 ABK70019.1 ABK70019.1 tsaD tsaD ABK71064.1 ABK71064.1 ABK73802.1 ABK73802.1 ABK75687.1 ABK75687.1 ABK72629.1 ABK72629.1 ABK71634.1 ABK71634.1 trmU trmU ABK76183.1 ABK76183.1 trmD trmD rlmN rlmN truB truB miaB miaB ABK75612.1 ABK75612.1 fmt fmt sun sun ABK73618.1 ABK73618.1 ABK72713.1 ABK72713.1 rluB rluB ABK71160.1 ABK71160.1 ABK76023.1 ABK76023.1 mraW mraW ABK70439.1 ABK70439.1 ABK74045.1 ABK74045.1 ksgA ksgA rsmI rsmI ABK71293.1 ABK71293.1 ABK76164.1 ABK76164.1 ABK75506.1 ABK75506.1 tilS tilS gltX-2 gltX-2 tgt tgt tadA tadA gidB gidB ABK72876.1 ABK72876.1 trmB trmB
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ABK70836.1Spou rRNA methylase family protein; Identified by match to protein family HMM PF00588. (214 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (291 aa)
ABK76013.1Conserved hypothetical protein; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. (155 aa)
ABK70019.1Peptidase M22, glycoprotease; Identified by match to protein family HMM PF00814. (214 aa)
tsaDO-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (340 aa)
ABK71064.1RNA methyltransferase, TrmH family protein, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. (154 aa)
ABK73802.1Ribosomal RNA adenine dimethylase family protein; Identified by match to protein family HMM PF00398; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (386 aa)
ABK75687.1RNA pseudouridine synthase family protein; Identified by match to protein family HMM PF00849. (291 aa)
ABK72629.1Conserved hypothetical protein. (232 aa)
ABK71634.1Identified by match to protein family HMM PF00899. (723 aa)
trmUtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (356 aa)
ABK76183.1Putative methyltransferase; Identified by match to protein family HMM PF03602; match to protein family HMM TIGR00095. (169 aa)
trmDtRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (225 aa)
rlmNRadical SAM enzyme, Cfr family protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (372 aa)
truBtRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (303 aa)
miaBtRNA-I(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (512 aa)
ABK75612.1Putative RNA methyltransferase; Cg2084; identified by match to protein family HMM PF01938; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (397 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (312 aa)
sunRibosomal RNA small subunit methyltransferase B; Identified by match to protein family HMM PF01029; match to protein family HMM PF01189; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (464 aa)
ABK73618.1Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (309 aa)
ABK72713.1Cytidine/deoxycytidylate deaminase, zinc-binding region; Identified by match to protein family HMM PF00383. (159 aa)
rluBRibosomal large subunit pseudouridine synthase B; Identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; Belongs to the pseudouridine synthase RsuA family. (247 aa)
ABK71160.1RNA methyltransferase, TrmH family protein; Identified by match to protein family HMM PF00588; match to protein family HMM PF08032; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (252 aa)
ABK76023.1tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. (282 aa)
mraWS-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (326 aa)
ABK70439.1Cytosine deaminase; Identified by match to protein family HMM PF00383. (146 aa)
ABK74045.1Methyltransferase type 11. (216 aa)
ksgADimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (297 aa)
rsmIConserved hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (278 aa)
ABK71293.123s ribosomal RNA methyltransferase; Identified by match to protein family HMM PF00588. (277 aa)
ABK76164.1tRNA-dihydrouridine synthase, putative; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (389 aa)
ABK75506.1RNA methyltransferase, TrmH family protein, group 3; Identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (314 aa)
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (322 aa)
gltX-2glutamyl-tRNA synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (292 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (414 aa)
tadACytidine and deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (149 aa)
gidBMethyltransferase GidB; Specifically methylates the N7 position of guanine in position 518 of 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (235 aa)
ABK72876.1Formyl transferase; Identified by match to protein family HMM PF00551; match to protein family HMM PF02911. (322 aa)
trmBtRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (240 aa)
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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