90 items (Mycolicibacterium smegmatis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ABK74969.1	enoyl-CoA hydratase; Identified by match to protein family HMM PF00378. (251 aa)
	ABK73153.1	Coenzyme A transferase, subunit B. (249 aa)
	ABK69721.1	Oxidoreductase, 2-nitropropane dioxygenase family protein; Identified by similarity to GB:AAF98273.1; match to protein family HMM PF03060. (358 aa)
	ABK72416.1	acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family. (382 aa)
	ABK75352.1	Short chain dehydrogenase; Identified by match to protein family HMM PF00106. (262 aa)
	ABK71994.1	Putative acyl-CoA dehydrogenase; Identified by match to protein family HMM PF00441; match to protein family HMM PF02770. (392 aa)
	ABK70325.1	Putative acyl-CoA dehydrogenase; Identified by match to protein family HMM PF00441; match to protein family HMM PF08028. (311 aa)
	ABK73596.1	Cytochrome p450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (429 aa)
	ABK74830.1	Nitrilotriacetate monooxygenase component B; Identified by match to protein family HMM PF01613. (189 aa)
	ABK73895.1	Biphenyl-2,3-diol 1,2-dioxygenase; Identified by match to protein family HMM PF00903. (299 aa)
	ABK71346.1	Pigment production hydroxylase; Identified by match to protein family HMM PF08028. (396 aa)
	kshB	Oxidoreductase, electron transfer component; Involved in the degradation of cholesterol. Catalyzes the introduction of a 9a-hydroxyl moiety into 1,4-androstadiene-3,17-dione (ADD) to yield the 9alpha-hydroxy-1,4-androstadiene-3,17-dione (9OHADD) intermediate which spontaneously form 3-hydroxy-9,10-seconandrost- 1,3,5(10)-triene-9,17-dione (HSA) via the meta-cleavage of ring B with concomitant aromatization of ring A. (353 aa)
	ABK76151.1	Putative acyl-CoA dehydrogenase; Identified by match to protein family HMM PF00441; match to protein family HMM PF02770. (714 aa)
	ABK70618.1	Cytochrome P450 107B1; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (414 aa)
	ABK70280.1	Putative cytochrome P450 135B1; Identified by match to protein family HMM PF00067. (447 aa)
	ABK74112.1	acyl-CoA dehydrogenase domain protein; Identified by match to protein family HMM PF00441; match to protein family HMM PF02770. (385 aa)
	ABK71267.1	Acyl dehydratase; Identified by match to protein family HMM PF01796. (140 aa)
	ABK69713.1	Nonspecific lipid-transfer protein. (406 aa)
	ABK71893.1	Cytochrome P450 monooxygenase; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (396 aa)
	ABK75124.1	Identified by match to protein family HMM PF01381; match to protein family HMM PF06114. (472 aa)
	ABK72736.1	Cytochrome p450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (437 aa)
	ABK70288.1	Cytochrome P450 superfamily protein; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (453 aa)
	ABK74307.1	Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970. (358 aa)
	ABK75020.1	NADH-fmn oxidoreductase; Identified by match to protein family HMM PF01613. (161 aa)
	ABK73430.1	Putative cytochrome P450 123; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (400 aa)
	ABK75448.1	Cytochrome p450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (428 aa)
	ABK73604.1	Cytochrome P450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (396 aa)
	ABK72320.1	Cytochrome P450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (410 aa)
	ABK75246.1	Cytochrome P450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (400 aa)
	ABK72693.1	Putative cytochrome P450 123; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (406 aa)
	ABK73801.1	2-Nitropropane dioxygenase; Identified by match to protein family HMM PF03060. (337 aa)
	ABK75456.1	NikQ protein; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (401 aa)
	ABK73207.1	Cytochrome P450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (411 aa)
	ABK71599.1	Cytochrome P450 109; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (400 aa)
	ABK75192.1	Cytochrome P450 51; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (451 aa)
	ABK71622.1	Putative acyl-CoA dehydrogenase; Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771. (392 aa)
	ABK70566.1	acyl-CoA dehydrogenase; Identified by match to protein family HMM PF00441; match to protein family HMM PF08028. (365 aa)
	ABK74402.1	acyl-CoA synthase; Identified by match to protein family HMM PF00501. (551 aa)
	ABK74294.1	Putative cytochrome P450 144; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (405 aa)
	ABK70714.1	P450 heme-thiolate protein; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (422 aa)
	ABK75049.1	Rieske [2Fe-2S] domain protein; Identified by match to protein family HMM PF00355. (359 aa)
	ABK73820.1	Cytochrome P450 FAS1; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (401 aa)
	ABK74247.1	Cytochrome P450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (455 aa)
	ABK69642.1	Cytochrome P450; Identified by match to protein family HMM PF00067. (484 aa)
	ABK73406.1	Cytochrome p450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (494 aa)
	ABK70910.1	Cytochrome P450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (479 aa)
	ABK70182.1	Cytochrome P450 monooxygenase; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (437 aa)
	ABK74703.1	Cytochrome P450-terp; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (416 aa)
	ABK70678.1	Cytochrome P450-terp; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (431 aa)
	ABK75676.1	FAD dependent oxidoreductase; Identified by match to protein family HMM PF00037; match to protein family HMM PF01266. (578 aa)
	ABK70939.1	Oxidoreductase, 2-nitropropane dioxygenase family protein; Identified by match to protein family HMM PF03060. (289 aa)
	ABK69685.1	Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771. (410 aa)
	ABK73186.1	AMP-binding enzyme; Identified by match to protein family HMM PF00501. (542 aa)
	ABK70966.1	acyl-CoA dehydrogenase, middle domain protein; Identified by match to protein family HMM PF00441; match to protein family HMM PF02770. (396 aa)
	ABK70900.1	Cytochrome P450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (402 aa)
	ABK75593.1	Medium chain acyl-CoA synthetase; Identified by match to protein family HMM PF00501. (550 aa)
	ABK73724.1	Rieske [2Fe-2S] domain protein; Identified by match to protein family HMM PF00355. (338 aa)
	ABK72971.1	Cytochrome P450-terp; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (411 aa)
	ABK71152.1	Cytochrome p450; Identified by match to protein family HMM PF00067. (494 aa)
	ABK71945.1	NikQ protein; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (418 aa)
	ABK71459.1	Cytochrome P450 superfamily protein; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (412 aa)
	ABK73356.1	C-5 sterol desaturase. (290 aa)
	ABK70591.1	Oxygenase KshA; Identified by match to protein family HMM PF00355. (386 aa)
	ABK74491.1	acyl-CoA dehydrogenase; Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771. (383 aa)
	ABK72155.1	Oxidoreductase, NAD/FAD-binding; Identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970. (351 aa)
	ABK71655.1	Cytochrome P450 107B1; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (421 aa)
	ABK76004.1	acyl-CoA dehydrogenase domain protein; Identified by match to protein family HMM PF00441; match to protein family HMM PF02770. (377 aa)
	ABK74576.1	2-methylcitrate dehydratase 2; Identified by match to protein family HMM PF03972. (504 aa)
	ABK70871.1	Cytochrome P450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (400 aa)
	ABK73860.1	Capreomycidine hydroxylase; Identified by match to protein family HMM PF00355. (364 aa)
	ABK73667.1	Putative cytochrome P450 126; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (419 aa)
	ABK75264.1	Conserved hypothetical protein; Identified by match to protein family HMM PF01796. (143 aa)
	ABK75580.1	acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family. (387 aa)
	ABK73022.1	Coenzyme A transferase, subunit A; Identified by match to protein family HMM PF01144. (295 aa)
	ABK74355.1	Linalool 8-monooxygenase; Belongs to the cytochrome P450 family. (430 aa)
	ABK69974.1	Linalool 8-monooxygenase; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (425 aa)
	ABK72784.1	C-5 sterol desaturase. (307 aa)
	ABK75029.1	Medium chain acyl-CoA synthetase; Identified by match to protein family HMM PF00501. (551 aa)
	ABK72697.1	Conserved hypothetical protein; Identified by match to protein family HMM PF01796. (149 aa)
	ABK72567.1	Cytochrome P450 hydroxylase; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (385 aa)
	ABK71361.1	Conserved hypothetical protein; Identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM TIGR01777. (302 aa)
	ABK70024.1	C-5 sterol desaturase. (304 aa)
	cyp142	P450 heme-thiolate protein; Involved in the utilization of cholesterol as the sole carbon and energy source by degrading the side chain. Primarily catalyzes the sequential oxidation of the terminal methyl of cholest-4-en-3-one into (25R)-26-hydroxycholest-4-en-3-one (alcohol), (25R)-26-oxocholest-4-en- 3-one (aldehyde), to finally yield the carboxylic acid (25R)-3- oxocholest-4-en-26-oate. Also able to sequentially oxidize cholesterol itself, not only cholest-4-en-3-one. (401 aa)
	ABK72460.1	Conserved hypothetical protein; Identified by match to protein family HMM PF01796. (300 aa)
	kshA	Rieske [2Fe-2S] domain protein; Involved in the degradation of cholesterol. Catalyzes the introduction of a 9a-hydroxyl moiety into 1,4-androstadiene-3,17-dione (ADD) to yield the 9alpha-hydroxy-1,4-androstadiene-3,17-dione (9OHADD) intermediate which spontaneously form 3-hydroxy-9,10-seconandrost- 1,3,5(10)-triene-9,17-dione (HSA) via the meta-cleavage of ring B with concomitant aromatization of ring A. (383 aa)
	ABK74714.1	Lipid-transfer protein. (387 aa)
	ABK73497.1	MaoC like domain, putative; Identified by match to protein family HMM PF01575. (137 aa)
	ABK70448.1	Conserved hypothetical protein; Identified by match to protein family HMM PF01796. (321 aa)
	ABK73563.1	Putative acyl-CoA dehydrogenase; Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771. (387 aa)
	cyp125	P450 heme-thiolate protein; Involved in the utilization of cholesterol as the sole carbon and energy source by degrading the side chain. Primarily catalyzes the sequential oxidation of the terminal methyl of cholest-4-en-3-one into (25S)-26-hydroxycholest-4-en-3-one (alcohol), (25S)-26-oxocholest-4-en- 3-one (aldehyde), to finally yield the carboxylic acid (25S)-3- oxocholest-4-en-26-oate. Also able to sequentially oxidize cholesterol itself, not only cholest-4-en-3-one. (427 aa)

Your Current Organism:

Mycolicibacterium smegmatis

NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABK69642.1	ABK70024.1	MSMEG_0968	MSMEG_0147	Cytochrome P450; Identified by match to protein family HMM PF00067.	C-5 sterol desaturase.	0.427
ABK69642.1	ABK72155.1	MSMEG_0968	MSMEG_2893	Cytochrome P450; Identified by match to protein family HMM PF00067.	Oxidoreductase, NAD/FAD-binding; Identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970.	0.591
ABK69642.1	ABK72784.1	MSMEG_0968	MSMEG_3666	Cytochrome P450; Identified by match to protein family HMM PF00067.	C-5 sterol desaturase.	0.435
ABK69642.1	ABK73186.1	MSMEG_0968	MSMEG_2231	Cytochrome P450; Identified by match to protein family HMM PF00067.	AMP-binding enzyme; Identified by match to protein family HMM PF00501.	0.508
ABK69642.1	ABK73207.1	MSMEG_0968	MSMEG_5853	Cytochrome P450; Identified by match to protein family HMM PF00067.	Cytochrome P450; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family.	0.464
ABK69642.1	ABK73356.1	MSMEG_0968	MSMEG_2812	Cytochrome P450; Identified by match to protein family HMM PF00067.	C-5 sterol desaturase.	0.422
ABK69642.1	ABK74307.1	MSMEG_0968	MSMEG_0295	Cytochrome P450; Identified by match to protein family HMM PF00067.	Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970.	0.595
ABK69642.1	ABK74402.1	MSMEG_0968	MSMEG_5914	Cytochrome P450; Identified by match to protein family HMM PF00067.	acyl-CoA synthase; Identified by match to protein family HMM PF00501.	0.516
ABK69642.1	ABK75029.1	MSMEG_0968	MSMEG_3687	Cytochrome P450; Identified by match to protein family HMM PF00067.	Medium chain acyl-CoA synthetase; Identified by match to protein family HMM PF00501.	0.519
ABK69642.1	ABK75593.1	MSMEG_0968	MSMEG_2241	Cytochrome P450; Identified by match to protein family HMM PF00067.	Medium chain acyl-CoA synthetase; Identified by match to protein family HMM PF00501.	0.514
ABK69642.1	kshB	MSMEG_0968	MSMEG_6039	Cytochrome P450; Identified by match to protein family HMM PF00067.	Oxidoreductase, electron transfer component; Involved in the degradation of cholesterol. Catalyzes the introduction of a 9a-hydroxyl moiety into 1,4-androstadiene-3,17-dione (ADD) to yield the 9alpha-hydroxy-1,4-androstadiene-3,17-dione (9OHADD) intermediate which spontaneously form 3-hydroxy-9,10-seconandrost- 1,3,5(10)-triene-9,17-dione (HSA) via the meta-cleavage of ring B with concomitant aromatization of ring A.	0.595
ABK69685.1	ABK69713.1	MSMEG_2191	MSMEG_6561	Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771.	Nonspecific lipid-transfer protein.	0.618
ABK69685.1	ABK70325.1	MSMEG_2191	MSMEG_6016	Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771.	Putative acyl-CoA dehydrogenase; Identified by match to protein family HMM PF00441; match to protein family HMM PF08028.	0.689
ABK69685.1	ABK70566.1	MSMEG_2191	MSMEG_5907	Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771.	acyl-CoA dehydrogenase; Identified by match to protein family HMM PF00441; match to protein family HMM PF08028.	0.889
ABK69685.1	ABK72416.1	MSMEG_2191	MSMEG_6008	Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771.	acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.	0.454
ABK69685.1	ABK73497.1	MSMEG_2191	MSMEG_5991	Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771.	MaoC like domain, putative; Identified by match to protein family HMM PF01575.	0.534
ABK69685.1	ABK74714.1	MSMEG_2191	MSMEG_5990	Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771.	Lipid-transfer protein.	0.557
ABK69685.1	ABK74969.1	MSMEG_2191	MSMEG_6001	Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771.	enoyl-CoA hydratase; Identified by match to protein family HMM PF00378.	0.595
ABK69685.1	ABK75580.1	MSMEG_2191	MSMEG_5996	Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771.	acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.	0.524
ABK69713.1	ABK69685.1	MSMEG_6561	MSMEG_2191	Nonspecific lipid-transfer protein.	Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771.	0.618