node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK70439.1 | cdd | MSMEG_4687 | MSMEG_1673 | Cytosine deaminase; Identified by match to protein family HMM PF00383. | Cytidine deaminase; Identified by match to protein family HMM PF00383; match to protein family HMM TIGR01354. | 0.853 |
ABK70439.1 | hisIE | MSMEG_4687 | MSMEG_3212 | Cytosine deaminase; Identified by match to protein family HMM PF00383. | phosphoribosyl-AMP pyrophosphatase/phosphoribosyl-ATP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.428 |
ABK70446.1 | ABK72801.1 | MSMEG_3472 | MSMEG_3471 | Conserved hypothetical protein; Identified by match to protein family HMM PF07958. | GTP cyclohydrolase. | 0.995 |
ABK70446.1 | ribD | MSMEG_3472 | MSMEG_3067 | Conserved hypothetical protein; Identified by match to protein family HMM PF07958. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.823 |
ABK72801.1 | ABK70446.1 | MSMEG_3471 | MSMEG_3472 | GTP cyclohydrolase. | Conserved hypothetical protein; Identified by match to protein family HMM PF07958. | 0.995 |
ABK72801.1 | ribD | MSMEG_3471 | MSMEG_3067 | GTP cyclohydrolase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.857 |
add | cdd | MSMEG_1676 | MSMEG_1673 | Adenosine deaminase; Identified by match to protein family HMM PF00962; match to protein family HMM TIGR01430; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | Cytidine deaminase; Identified by match to protein family HMM PF00383; match to protein family HMM TIGR01354. | 0.876 |
add | purH | MSMEG_1676 | MSMEG_5515 | Adenosine deaminase; Identified by match to protein family HMM PF00962; match to protein family HMM TIGR01430; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | Bifunctional purine biosynthesis protein PurH; Identified by match to protein family HMM PF01808; match to protein family HMM PF02142; match to protein family HMM TIGR00355. | 0.462 |
cdd | ABK70439.1 | MSMEG_1673 | MSMEG_4687 | Cytidine deaminase; Identified by match to protein family HMM PF00383; match to protein family HMM TIGR01354. | Cytosine deaminase; Identified by match to protein family HMM PF00383. | 0.853 |
cdd | add | MSMEG_1673 | MSMEG_1676 | Cytidine deaminase; Identified by match to protein family HMM PF00383; match to protein family HMM TIGR01354. | Adenosine deaminase; Identified by match to protein family HMM PF00962; match to protein family HMM TIGR01430; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | 0.876 |
folD | folE | MSMEG_1647 | MSMEG_6104 | Tetrahydrofolate dehydrogenase/cyclohydrolase FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | 0.548 |
folD | purH | MSMEG_1647 | MSMEG_5515 | Tetrahydrofolate dehydrogenase/cyclohydrolase FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Bifunctional purine biosynthesis protein PurH; Identified by match to protein family HMM PF01808; match to protein family HMM PF02142; match to protein family HMM TIGR00355. | 0.982 |
folD | ribBA | MSMEG_1647 | MSMEG_3072 | Tetrahydrofolate dehydrogenase/cyclohydrolase FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.486 |
folD | ribD | MSMEG_1647 | MSMEG_3067 | Tetrahydrofolate dehydrogenase/cyclohydrolase FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.454 |
folE | folD | MSMEG_6104 | MSMEG_1647 | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | Tetrahydrofolate dehydrogenase/cyclohydrolase FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.548 |
folE | hisIE | MSMEG_6104 | MSMEG_3212 | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | phosphoribosyl-AMP pyrophosphatase/phosphoribosyl-ATP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.685 |
folE | ribBA | MSMEG_6104 | MSMEG_3072 | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.961 |
folE | ribD | MSMEG_6104 | MSMEG_3067 | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.563 |
hisIE | ABK70439.1 | MSMEG_3212 | MSMEG_4687 | phosphoribosyl-AMP pyrophosphatase/phosphoribosyl-ATP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | Cytosine deaminase; Identified by match to protein family HMM PF00383. | 0.428 |
hisIE | folE | MSMEG_3212 | MSMEG_6104 | phosphoribosyl-AMP pyrophosphatase/phosphoribosyl-ATP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | 0.685 |