STRINGSTRING
ABK71747.1 ABK71747.1 ABK73865.1 ABK73865.1 ABK69804.1 ABK69804.1 ABK70651.1 ABK70651.1 ABK72105.1 ABK72105.1 ABK75850.1 ABK75850.1 ABK73988.1 ABK73988.1 leuC leuC leuD leuD ABK72227.1 ABK72227.1 ABK70728.1 ABK70728.1 aroQ-2 aroQ-2 ABK71553.1 ABK71553.1 ABK70503.1 ABK70503.1 dapA dapA ABK71327.1 ABK71327.1 rfbB rfbB ABK70216.1 ABK70216.1 ABK76145.1 ABK76145.1 ABK73491.1 ABK73491.1 ABK76059.1 ABK76059.1 ilvD-2 ilvD-2 hutU hutU ABK75999.1 ABK75999.1 ABK69737.1 ABK69737.1 ABK72688.1 ABK72688.1 ABK70859.1 ABK70859.1 hemB hemB hemD hemD ABK74527.1 ABK74527.1 ABK72063.1 ABK72063.1 ABK72195.1 ABK72195.1 ABK70278.1 ABK70278.1 ABK71627.1 ABK71627.1 ABK74496.1 ABK74496.1 nthA nthA ABK72826.1 ABK72826.1 ABK74377.1 ABK74377.1 edd edd ABK75292.1 ABK75292.1 ABK73013.1 ABK73013.1 ilvD ilvD menC menC ABK74269.1 ABK74269.1 PduC PduC ABK69789.1 ABK69789.1 nnrD nnrD ABK72311.1 ABK72311.1 ABK70305.1 ABK70305.1 aroQ aroQ ABK74157.1 ABK74157.1 ABK71952.1 ABK71952.1 ABK71634.1 ABK71634.1 ABK71450.1 ABK71450.1 ABK70332.1 ABK70332.1 ABK71511.1 ABK71511.1 ABK73966.1 ABK73966.1 ABK73370.1 ABK73370.1 ABK70291.1 ABK70291.1 ABK70284.1 ABK70284.1 ABK73786.1 ABK73786.1 ABK71507.1 ABK71507.1 ABK74376.1 ABK74376.1 ABK75145.1 ABK75145.1 ABK74393.1 ABK74393.1 ABK72204.1 ABK72204.1 ABK72354.1 ABK72354.1 fumC fumC ABK75142.1 ABK75142.1 ABK69885.1 ABK69885.1 eno eno ABK71003.1 ABK71003.1 ABK73808.1 ABK73808.1 ABK75265.1 ABK75265.1 ABK71830.1 ABK71830.1 ABK75596.1 ABK75596.1 ABK74969.1 ABK74969.1 cynT cynT GudD GudD ABK73956.1 ABK73956.1 ABK71577.1 ABK71577.1 ABK72996.1 ABK72996.1 ABK71644.1 ABK71644.1 ABK74740.1 ABK74740.1 pheA pheA ABK74576.1 ABK74576.1 ABK74938.1 ABK74938.1 ABK73095.1 ABK73095.1 leuD-2 leuD-2 leuC-2 leuC-2 ABK75342.1 ABK75342.1 ABK73327.1 ABK73327.1 ABK72215.1 ABK72215.1 ABK69565.1 ABK69565.1 acnA acnA hisB hisB trpB trpB trpA trpA ABK72037.1 ABK72037.1 ABK72253.1 ABK72253.1 ABK71762.1 ABK71762.1 ABK73211.1 ABK73211.1 ectC ectC ABK73602.1 ABK73602.1 ABK70001.1 ABK70001.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABK71747.1ZbpA protein; Identified by match to protein family HMM PF01575. (150 aa)
ABK73865.1Identified by match to protein family HMM PF00378. (260 aa)
ABK69804.1Identified by match to protein family HMM PF00378. (268 aa)
ABK70651.1enoyl-CoA hydratase/isomerase; Identified by match to protein family HMM PF00378. (273 aa)
ABK72105.1Identified by match to protein family HMM PF00378; Belongs to the enoyl-CoA hydratase/isomerase family. (289 aa)
ABK75850.1enoyl-CoA hydratase; Identified by match to protein family HMM PF00378. (273 aa)
ABK73988.1Probable enoyl-CoA hydratase; Identified by match to protein family HMM PF00378. (235 aa)
leuC3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (484 aa)
leuD3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (197 aa)
ABK72227.13-isopropylmalate dehydratase small subunit; Identified by match to protein family HMM TIGR02087; Belongs to the LeuD family. (175 aa)
ABK70728.13-isopropylmalate dehydratase large subunit; Identified by match to protein family HMM PF00330. (413 aa)
aroQ-2Dehydroquinase dehydratase, type II; Identified by match to protein family HMM PF01220. (191 aa)
ABK71553.1Hypothetical protein; Identified by Glimmer2; putative. (234 aa)
ABK70503.1Conserved hypothetical protein; Identified by match to protein family HMM PF06187. (396 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (300 aa)
ABK71327.1enoyl-CoA hydratase; Identified by match to protein family HMM PF00378; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa)
rfbBdTDP-glucose 4,6-dehydratase; Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6- deoxy-D-xylo-4-hexulose via a three-step process involving oxidation, dehydration and reduction (By similarity). Involved in the biosynthesis of the dTDP-L-rhamnose which is a component of the critical linker, D- N-acetylglucosamine-L-rhamnose disaccharide, which connects the galactan region of arabinogalactan to peptidoglycan via a phosphodiester linkage. (331 aa)
ABK70216.1enoyl-CoA hydratase; Identified by match to protein family HMM PF00378; Belongs to the enoyl-CoA hydratase/isomerase family. (254 aa)
ABK76145.1enoyl-CoA hydratase; Identified by match to protein family HMM PF00378. (312 aa)
ABK73491.1Conserved hypothetical protein; Belongs to the UPF0336 family. (169 aa)
ABK76059.1Conserved hypothetical protein; Belongs to the UPF0336 family. (158 aa)
ilvD-2Dihydroxy-acid dehydratase; Identified by match to protein family HMM PF00920; match to protein family HMM TIGR00110; Belongs to the IlvD/Edd family. (622 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (552 aa)
ABK75999.1Dihydrodipicolinate synthetase; Identified by match to protein family HMM PF00701; Belongs to the DapA family. (295 aa)
ABK69737.1Aconitate hydratase, putative; Identified by match to protein family HMM PF00330; match to protein family HMM PF00694; match to protein family HMM TIGR01342. (654 aa)
ABK72688.16-oxocamphor hydrolase; Identified by match to protein family HMM PF00378. (271 aa)
ABK70859.1Probable enoyl-CoA hydratase; Identified by match to protein family HMM PF00378. (235 aa)
hemBDelta-aminolevulinic acid dehydratase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family. (326 aa)
hemDuroporphyrinogen-III synthase; Identified by match to protein family HMM PF00590; match to protein family HMM PF02602. (610 aa)
ABK74527.1Conserved hypothetical protein; Belongs to the UPF0336 family. (177 aa)
ABK72063.1Dihydrodipicolinate synthase; Identified by match to protein family HMM PF00701; Belongs to the DapA family. (310 aa)
ABK72195.1Glycerol dehydratase large subunit; Identified by match to protein family HMM PF02286. (754 aa)
ABK70278.1Coenzyme B12-dependent glycerol dehydrogenase small subunit. (119 aa)
ABK71627.1Dihydroxy-acid dehydratase; Identified by match to protein family HMM PF00920; Belongs to the IlvD/Edd family. (564 aa)
ABK74496.1uroporphyrinogen-III synthetase; Identified by match to protein family HMM PF00486; match to protein family HMM PF02602. (385 aa)
nthANitrile hydratase, alpha subunit; Identified by match to protein family HMM PF02979; match to protein family HMM TIGR01323. (206 aa)
ABK72826.1Nitrile hydratase. (246 aa)
ABK74377.1Identified by match to protein family HMM PF00378. (250 aa)
eddPhosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (609 aa)
ABK75292.1P40 protein. (330 aa)
ABK73013.1enoyl-CoA hydratase/isomerase; Identified by match to protein family HMM PF00378. (301 aa)
ilvDDihydroxy-acid dehydratase; Identified by match to protein family HMM PF00920; match to protein family HMM TIGR00110; Belongs to the IlvD/Edd family. (571 aa)
menCO-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (321 aa)
ABK74269.1Coenzyme B12-dependent glycerol dehydrogenase small subunit; Identified by match to protein family HMM PF02287. (142 aa)
PduCGlycerol dehydratase large subunit; Identified by match to protein family HMM PF02286. (570 aa)
ABK69789.1Propanediol utilization: dehydratase, medium subunit; Identified by match to protein family HMM PF02288. (200 aa)
nnrDCarbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...] (470 aa)
ABK72311.1enoyl-CoA hydratase; Identified by match to protein family HMM PF00378. (265 aa)
ABK70305.1Identified by match to protein family HMM PF00378. (262 aa)
aroQ3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (145 aa)
ABK74157.1MaoC like domain protein; Identified by match to protein family HMM PF01575. (277 aa)
ABK71952.1Probable enoyl-CoA hydratase; Identified by match to protein family HMM PF00378. (255 aa)
ABK71634.1Identified by match to protein family HMM PF00899. (723 aa)
ABK71450.1enoyl-CoA hydratase; Identified by match to protein family HMM PF00378. (252 aa)
ABK70332.13-hydroxybutyryl-CoA dehydratase; Identified by match to protein family HMM PF00378. (262 aa)
ABK71511.1Conserved hypothetical protein. (395 aa)
ABK73966.1Conserved hypothetical protein; Identified by match to protein family HMM PF06187. (387 aa)
ABK73370.1Identified by match to protein family HMM PF01575. (144 aa)
ABK70291.1enoyl-CoA hydratase/isomerase; Identified by match to protein family HMM PF00378. (261 aa)
ABK70284.1enoyl-CoA hydratase; Identified by match to protein family HMM PF00378; Belongs to the enoyl-CoA hydratase/isomerase family. (249 aa)
ABK73786.1MoaC domain protein; Identified by match to protein family HMM PF01575. (162 aa)
ABK71507.1Probable enoyl-CoA hydratase; Identified by match to protein family HMM PF00378. (260 aa)
ABK74376.1enoyl-CoA hydratase, putative; Identified by match to protein family HMM PF00378. (318 aa)
ABK75145.1enoyl-CoA hydratase/isomerase; Identified by match to protein family HMM PF00378. (252 aa)
ABK74393.1Carbonic anhydrase; Identified by match to protein family HMM PF00484. (163 aa)
ABK72204.1Putative pterin-4-alpha-carbinolamine dehydratase; Identified by match to protein family HMM PF01329. (94 aa)
ABK72354.1Siderophore binding protein; Identified by match to protein family HMM PF00132. (173 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (468 aa)
ABK75142.1Cystathionine beta-synthase; Identified by match to protein family HMM PF00291; match to protein family HMM PF00571; match to protein family HMM TIGR01137. (463 aa)
ABK69885.1Probable enoyl-CoA hydratase; Identified by match to protein family HMM PF00378; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
ABK71003.1enoyl-CoA hydratase; Identified by match to protein family HMM PF00378. (259 aa)
ABK73808.1enoyl-CoA hydratase; Identified by match to protein family HMM PF00378; Belongs to the enoyl-CoA hydratase/isomerase family. (243 aa)
ABK75265.1enoyl-CoA hydratase; Identified by match to protein family HMM PF00378. (315 aa)
ABK71830.12-keto-4-pentenoate hydratase; Identified by match to protein family HMM PF01689. (261 aa)
ABK75596.1Putative peroxisomal multifunctional enzyme type 2; Identified by match to protein family HMM PF01575. (286 aa)
ABK74969.1enoyl-CoA hydratase; Identified by match to protein family HMM PF00378. (251 aa)
cynTCarbonic anhydrase; Catalyzes the reversible hydration of carbon dioxide to form bicarbonate; Belongs to the beta-class carbonic anhydrase family. (206 aa)
GudDGlucarate dehydratase; Identified by match to protein family HMM PF01188; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (449 aa)
ABK73956.1Glucarate dehydratase; Identified by match to protein family HMM PF01188; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (423 aa)
ABK71577.15-dehydro-4-deoxyglucarate dehydratase; Identified by match to protein family HMM PF00701; Belongs to the DapA family. (307 aa)
ABK72996.1Thiocyanate hydrolase gamma subunit; Identified by match to protein family HMM PF02979. (236 aa)
ABK71644.1Diol dehydrase gamma subunit. (114 aa)
ABK74740.1Glycerol dehydratase large subunit; Identified by match to protein family HMM PF02286. (757 aa)
pheAPrephenate dehydratase; Identified by match to protein family HMM PF00800; match to protein family HMM PF01842. (310 aa)
ABK74576.12-methylcitrate dehydratase 2; Identified by match to protein family HMM PF03972. (504 aa)
ABK74938.1enoyl-CoA hydratase; Identified by match to protein family HMM PF00378; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa)
ABK73095.1Probable enoyl-CoA hydratase; Identified by match to protein family HMM PF00378; Belongs to the enoyl-CoA hydratase/isomerase family. (259 aa)
leuD-23-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (182 aa)
leuC-23-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (422 aa)
ABK75342.1Identified by match to protein family HMM PF03972. (477 aa)
ABK73327.1Isomerase; Identified by match to protein family HMM PF01188; match to protein family HMM PF02746; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (375 aa)
ABK72215.1Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (545 aa)
ABK69565.1enoyl-CoA hydratase/isomerase; Identified by match to protein family HMM PF00378; Belongs to the enoyl-CoA hydratase/isomerase family. (273 aa)
acnAAconitate hydratase 1; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. The apo form of AcnA functions as a RNA-binding regulatory protein. Could catalyze the hydration of 2-methyl-cis- aconitate to yield (2R,3S)-2-methylisocitrate. (943 aa)
hisBImidazoleglycerol-phosphate dehydratase; Identified by match to protein family HMM PF00475. (206 aa)
trpBTryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (425 aa)
trpATryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (262 aa)
ABK72037.1Conserved hypothetical protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (433 aa)
ABK72253.1enoyl-CoA hydratase; Identified by match to protein family HMM PF00378; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
ABK71762.1O-succinylbenzoate synthase; Identified by match to protein family HMM PF01188; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (350 aa)
ABK73211.1enoyl-CoA hydratase; Identified by match to protein family HMM PF00378. (255 aa)
ectCEctoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (130 aa)
ABK73602.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (772 aa)
ABK70001.1Identified by match to protein family HMM PF00378; Belongs to the enoyl-CoA hydratase/isomerase family. (263 aa)
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.