STRINGSTRING
ABK73026.1 ABK73026.1 ABK70713.1 ABK70713.1 ABK75020.1 ABK75020.1 ABK72089.1 ABK72089.1 ABK72515.1 ABK72515.1 ABK70154.1 ABK70154.1 ABK74730.1 ABK74730.1 ABK71441.1 ABK71441.1 ABK69650.1 ABK69650.1 ABK75483.1 ABK75483.1 ABK71192.1 ABK71192.1 ABK70147.1 ABK70147.1 ABK73526.1 ABK73526.1 ABK73352.1 ABK73352.1 ABK73922.1 ABK73922.1 ABK76221.1 ABK76221.1 ABK75175.1 ABK75175.1 ABK72521.1 ABK72521.1 ABK70141.1 ABK70141.1 deoC deoC ABK75529.1 ABK75529.1 ABK71016.1 ABK71016.1 ABK72488.1 ABK72488.1 ABK74849.1 ABK74849.1 ABK70235.1 ABK70235.1 ABK72225.1 ABK72225.1 ABK71648.1 ABK71648.1 ABK71069.1 ABK71069.1 ABK72176.1 ABK72176.1 ABK69916.1 ABK69916.1 ABK71738.1 ABK71738.1 ABK76239.1 ABK76239.1 cdd cdd ABK71862.1 ABK71862.1 ABK75925.1 ABK75925.1 ABK71343.1 ABK71343.1 pcaD pcaD ABK72737.1 ABK72737.1 ABK73752.1 ABK73752.1 ABK72871.1 ABK72871.1 ABK73484.1 ABK73484.1 ABK71883.1 ABK71883.1 ABK72848.1 ABK72848.1 hmgA hmgA ABK71272.1 ABK71272.1 ABK72024.1 ABK72024.1 ABK71547.1 ABK71547.1 ABK74401.1 ABK74401.1 rnhB rnhB ABK74659.1 ABK74659.1 ABK75536.1 ABK75536.1 ABK73128.1 ABK73128.1 ABK74421.1 ABK74421.1 ABK75492.1 ABK75492.1 pcaH pcaH pcaG pcaG pcaB pcaB gpsI gpsI dut dut ABK71075.1 ABK71075.1 ABK73848.1 ABK73848.1 ABK75969.1 ABK75969.1 ABK73204.1 ABK73204.1 ABK71196.1 ABK71196.1 ABK70166.1 ABK70166.1 ABK70053.1 ABK70053.1 ABK73340.1 ABK73340.1 deoC-2 deoC-2 ABK75308.1 ABK75308.1 ABK74674.1 ABK74674.1 ABK71037.1 ABK71037.1 ABK69865.1 ABK69865.1 ABK70675.1 ABK70675.1 ABK73987.1 ABK73987.1 ABK73064.1 ABK73064.1 ABK73134.1 ABK73134.1 ABK70959.1 ABK70959.1 ABK69773.1 ABK69773.1 ABK71380.1 ABK71380.1 ABK75382.1 ABK75382.1 ABK71527.1 ABK71527.1 ABK71899.1 ABK71899.1 ABK70348.1 ABK70348.1 ABK75249.1 ABK75249.1 dgt dgt ABK73620.1 ABK73620.1 ABK76171.1 ABK76171.1 ABK73999.1 ABK73999.1 mhpB mhpB mhpA mhpA ABK74549.1 ABK74549.1 rdgB rdgB rph rph ABK75543.1 ABK75543.1 deaD deaD ABK70784.1 ABK70784.1 ABK74152.1 ABK74152.1 xseA xseA xseB xseB mazG mazG ABK70499.1 ABK70499.1 rnhA rnhA ABK71798.1 ABK71798.1 ABK75365.1 ABK75365.1 ABK69711.1 ABK69711.1 ABK73221.1 ABK73221.1 ABK71665.1 ABK71665.1 ABK73876.1 ABK73876.1 ABK69790.1 ABK69790.1 bphI-2 bphI-2 mhpF mhpF ABK71830.1 ABK71830.1 ABK75580.1 ABK75580.1 ABK74830.1 ABK74830.1 ABK73895.1 ABK73895.1 ABK74305.1 ABK74305.1 ABK71346.1 ABK71346.1 ABK70526.1 ABK70526.1 ABK73446.1 ABK73446.1 ABK69583.1 ABK69583.1 ABK73507.1 ABK73507.1 surE surE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABK73026.1Hypothetical protein; Identified by Glimmer2; putative. (97 aa)
ABK70713.1Amidohydrolase 3; Identified by match to protein family HMM PF07969. (423 aa)
ABK75020.1NADH-fmn oxidoreductase; Identified by match to protein family HMM PF01613. (161 aa)
ABK72089.1Identified by match to protein family HMM PF07969. (545 aa)
ABK72515.1Identified by match to protein family HMM PF00903. (199 aa)
ABK70154.1Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; Identified by match to protein family HMM PF01315; match to protein family HMM PF02738. (704 aa)
ABK74730.1Oxidoreductase, molybdopterin-binding subunit; Identified by match to protein family HMM PF00941; match to protein family HMM PF03450. (331 aa)
ABK71441.1Oxidoreductase; Identified by match to protein family HMM PF00111; match to protein family HMM PF01799. (173 aa)
ABK69650.1Xanthine dehydrogenase; Identified by match to protein family HMM PF02625. (386 aa)
ABK75483.1Carbon monoxide dehydrogenase medium chain; Identified by match to protein family HMM PF00941; match to protein family HMM PF03450. (296 aa)
ABK71192.1[2Fe-2S] binding domain protein; Identified by match to protein family HMM PF00111; match to protein family HMM PF01799. (158 aa)
ABK70147.1Carbon-monoxide dehydrogenase, large subunit; Identified by match to protein family HMM PF01315; match to protein family HMM PF02738; match to protein family HMM TIGR02416. (799 aa)
ABK73526.1Carbon monoxide dehydrogenase F protein; Identified by match to protein family HMM PF02625. (245 aa)
ABK73352.1Phytase. (382 aa)
ABK73922.1Oxygenase. (105 aa)
ABK76221.1Oxidoreductase; Identified by match to protein family HMM PF01315; match to protein family HMM PF02738. (721 aa)
ABK75175.1Putative aldehyde or xanthine dehydrogenase, molybdopterin binding subunit protein; Identified by match to protein family HMM PF00941. (324 aa)
ABK72521.1Twin-arginine translocation pathway signal; Identified by match to protein family HMM PF00111; match to protein family HMM PF01799. (205 aa)
ABK70141.1HD domain protein; Identified by match to protein family HMM PF01966; match to protein family HMM TIGR00277. (199 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (227 aa)
ABK75529.1Twin-arginine translocation pathway signal; Identified by match to protein family HMM PF07969. (536 aa)
ABK71016.1Prophage Lp1 protein 5; Identified by match to protein family HMM PF07553. (132 aa)
ABK72488.1Putative oxidoreductase; Identified by match to protein family HMM PF00111; match to protein family HMM PF01315; match to protein family HMM PF01799; match to protein family HMM PF02738. (893 aa)
ABK74849.1FAD binding domain in molybdopterin dehydrogenase protein; Identified by match to protein family HMM PF00941. (294 aa)
ABK70235.1Secreted protein. (780 aa)
ABK72225.15-carboxymethyl-2-hydroxymuconate delta-isomerase; Identified by match to protein family HMM PF01557. (206 aa)
ABK71648.1NTP pyrophosphohydrolase; Identified by match to protein family HMM PF00293. (173 aa)
ABK71069.1Oxygenase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494. (501 aa)
ABK72176.1ATP-dependent RNA helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. (460 aa)
ABK69916.1Conserved hypothetical protein. (149 aa)
ABK71738.1Pyrimidine-specific ribonucleoside hydrolase RihA; Identified by match to protein family HMM PF01156. (350 aa)
ABK76239.1FAD dependent oxidoreductase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494. (514 aa)
cddCytidine deaminase; Identified by match to protein family HMM PF00383; match to protein family HMM TIGR01354. (128 aa)
ABK71862.1AmiB; Identified by match to protein family HMM PF01546; match to protein family HMM TIGR01891; Belongs to the peptidase M20A family. (385 aa)
ABK75925.1Pentachlorophenol 4-monooxygenase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494. (382 aa)
ABK71343.1Amidohydrolase; Identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; Belongs to the peptidase M20A family. (394 aa)
pcaD3-oxoadipate enol-lactonase; Identified by match to protein family HMM PF00561; match to protein family HMM TIGR02427. (258 aa)
ABK72737.1Muconate cycloisomerase; Identified by match to protein family HMM PF01188; match to protein family HMM PF02746; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (367 aa)
ABK73752.1Muconolactone delta-isomerase 1; Identified by match to protein family HMM PF02426; Belongs to the muconolactone Delta-isomerase family. (94 aa)
ABK72871.1NADH pyrophosphatase; Identified by match to protein family HMM PF00293. (311 aa)
ABK73484.1Monooxygenase; Identified by match to protein family HMM PF01494. (391 aa)
ABK71883.12,3-dihydroxybiphenyl 1,2-dioxygenase; Identified by match to protein family HMM PF00903. (307 aa)
ABK72848.1Putative HpcE protein; Identified by match to protein family HMM PF01557. (287 aa)
hmgAHomogentisate 1,2-dioxygenase; Identified by match to protein family HMM PF04209. (367 aa)
ABK71272.1Identified by match to protein family HMM PF01557. (291 aa)
ABK72024.1Flavin-type hydroxylase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494. (494 aa)
ABK71547.1DoxX subfamily protein, putative; Identified by match to protein family HMM PF07681. (280 aa)
ABK74401.15-carboxymethyl-2-hydroxymuconate delta-isomerase; Identified by match to protein family HMM PF01557. (259 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (272 aa)
ABK74659.1Carbon-monoxide dehydrogenase; Identified by match to protein family HMM PF01315; match to protein family HMM PF02738. (777 aa)
ABK75536.1Nicotine dehydrogenase chain A; Identified by match to protein family HMM PF00941. (293 aa)
ABK73128.1[2Fe-2S] binding domain protein; Identified by match to protein family HMM PF00111; match to protein family HMM PF01799. (168 aa)
ABK74421.1Identified by match to protein family HMM PF01557. (285 aa)
ABK75492.1Monooxygenase, FAD-binding; Identified by match to protein family HMM PF01494. (535 aa)
pcaHProtocatechuate 3,4-dioxygenase, beta subunit; Identified by match to protein family HMM PF00775; match to protein family HMM TIGR02422. (248 aa)
pcaGProtocatechuate 3,4-dioxygenase, alpha subunit; Identified by match to protein family HMM PF00775; match to protein family HMM TIGR02423. (185 aa)
pcaB3-carboxy-cis,cis-muconate cycloisomerase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR02426. (400 aa)
gpsIGuanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (763 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (154 aa)
ABK71075.1Biphenyl-2,3-diol 1,2-dioxygenase 1; Identified by match to protein family HMM PF00903. (300 aa)
ABK73848.12-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; Identified by match to protein family HMM PF00561. (286 aa)
ABK75969.1Identified by match to protein family HMM PF01230. (205 aa)
ABK73204.1Polyketide cyclase; Identified by match to protein family HMM PF04199. (262 aa)
ABK71196.1Carbon-monoxide dehydrogenase; Identified by match to protein family HMM PF01315; match to protein family HMM PF02738. (786 aa)
ABK70166.1Carbon monoxide dehydrogenase, medium chain; Identified by match to protein family HMM PF00941. (272 aa)
ABK70053.1[2Fe-2S] binding domain protein; Identified by match to protein family HMM PF00111; match to protein family HMM PF01799. (161 aa)
ABK73340.1Monooxygenase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494. (402 aa)
deoC-2Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (231 aa)
ABK75308.1TM2 domain protein; Identified by match to protein family HMM PF05154. (95 aa)
ABK74674.1DoxX subfamily protein, putative; Identified by match to protein family HMM PF07681. (291 aa)
ABK71037.1Oxidoreductase; Identified by match to protein family HMM PF01494. (408 aa)
ABK69865.1Metal-dependent phosphohydrolase; Identified by match to protein family HMM PF01966; match to protein family HMM TIGR00277. (218 aa)
ABK70675.1Conserved hypothetical protein. (120 aa)
ABK73987.1Monooxygenase, FAD-binding; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494. (382 aa)
ABK73064.1Amidohydrolase 3; Identified by match to protein family HMM PF07969. (530 aa)
ABK73134.1DEAD/DEAH box helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851; match to protein family HMM PF08148. (912 aa)
ABK70959.1Cyclase; Identified by match to protein family HMM PF04199. (272 aa)
ABK69773.1Muconolactone delta-isomerase; Identified by match to protein family HMM PF02426; Belongs to the muconolactone Delta-isomerase family. (93 aa)
ABK71380.1Cyclase. (327 aa)
ABK75382.1Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (311 aa)
ABK71527.14-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (346 aa)
ABK71899.1Amidohydrolase; Identified by match to protein family HMM PF01979; match to protein family HMM PF07969. (602 aa)
ABK70348.1Integral membrane protein; Identified by match to protein family HMM PF07681. (136 aa)
ABK75249.1Glyoxalase/bleomycin resistance protein/dioxygenase; Identified by match to protein family HMM PF00903. (138 aa)
dgtDeoxyguanosinetriphosphate triphosphohydrolase; Identified by match to protein family HMM PF01966; match to protein family HMM TIGR01353; Belongs to the dGTPase family. Type 2 subfamily. (428 aa)
ABK73620.1Conserved hypothetical protein. (105 aa)
ABK76171.1Salicylate hydroxylase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494. (382 aa)
ABK73999.1Cyclase; Identified by match to protein family HMM PF04199. (328 aa)
mhpBMetapyrocatechase 1; Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6- ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family. (306 aa)
mhpA3-(3-hydroxy-phenyl)propionate hydroxylase; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI). (563 aa)
ABK74549.12-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase; Identified by match to protein family HMM PF00561. (302 aa)
rdgBNon-canonical purine NTP pyrophosphatase, RdgB/HAM1 family protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (200 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (259 aa)
ABK75543.1RemO protein; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494. (408 aa)
deaDATP-dependent rna helicase, dead/deah box family protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (581 aa)
ABK70784.1DoxX subfamily protein, putative; Identified by match to protein family HMM PF07681. (186 aa)
ABK74152.1DoxX subfamily protein, putative; Identified by match to protein family HMM PF07681. (174 aa)
xseAExodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (404 aa)
xseBExodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (70 aa)
mazGTranscriptional regulator, MazG family protein; Required to maintain the full capacity of the mycobacteria to respond to oxidative stress via the degradation of the oxidation- induced damaged nucleotides. It hydrolyzes all canonical (d)NTPs, as well as the mutagenic dUTP and 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'- triphosphate (8-oxo-dGTP). Also involved in the transcriptional activation of RelA in response to oxidative stress. (324 aa)
ABK70499.1Conserved hypothetical protein. (409 aa)
rnhARNase H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (159 aa)
ABK71798.1Conserved hypothetical protein. (325 aa)
ABK75365.1Oxidoreductase; Identified by match to protein family HMM PF01494. (402 aa)
ABK69711.1Putative cyanamide hydratase; Identified by match to protein family HMM PF01966. (199 aa)
ABK73221.1Nicotine dehydrogenase; Identified by match to protein family HMM PF01315; match to protein family HMM PF02738. (784 aa)
ABK71665.1Carbon monoxide dehydrogenase medium chain; Identified by match to protein family HMM PF00941; match to protein family HMM PF03450. (295 aa)
ABK73876.1[2Fe-2S] binding domain protein; Identified by match to protein family HMM PF00111; match to protein family HMM PF01799. (170 aa)
ABK69790.1Lipid-transfer protein. (347 aa)
bphI-24-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (349 aa)
mhpFAcetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (321 aa)
ABK71830.12-keto-4-pentenoate hydratase; Identified by match to protein family HMM PF01689. (261 aa)
ABK75580.1acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family. (387 aa)
ABK74830.1Nitrilotriacetate monooxygenase component B; Identified by match to protein family HMM PF01613. (189 aa)
ABK73895.1Biphenyl-2,3-diol 1,2-dioxygenase; Identified by match to protein family HMM PF00903. (299 aa)
ABK74305.12-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase; Identified by match to protein family HMM PF00561. (292 aa)
ABK71346.1Pigment production hydroxylase; Identified by match to protein family HMM PF08028. (396 aa)
ABK70526.1Antibiotic biosynthesis monooxygenase domain protein; Identified by match to protein family HMM PF03992. (105 aa)
ABK73446.12,6-dihydroxypyridine hydroxylase; Identified by match to protein family HMM PF01494. (396 aa)
ABK69583.1Fumarylacetoacetate; Identified by match to protein family HMM PF01557. (301 aa)
ABK73507.1Lactoylglutathione lyase; Identified by match to protein family HMM PF00903. (151 aa)
surEAcid phosphatase SurE; Identified by match to protein family HMM PF01975; match to protein family HMM TIGR00087. (259 aa)
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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