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| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (398 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (343 aa) |
| | ABK75823.1 | Glutamine synthetase; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family. (430 aa) |
| | ABK70330.1 | Glutamine synthetase; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family. (459 aa) |
| | cobG | precorrin-3B synthase; Identified by match to protein family HMM PF03460; match to protein family HMM TIGR02435. (372 aa) |
| | ABK75384.1 | Pyruvate dehydrogenase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. (576 aa) |
| | ABK71729.1 | Peptidase M20D, amidohydrolase; Identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891. (409 aa) |
| | ABK75477.1 | N-carbamoyl-L-amino acid amidohydrolase; Identified by match to protein family HMM PF01546; match to protein family HMM TIGR01879. (438 aa) |
| | ABK73215.1 | N-carbamoyl-L-amino acid amidohydrolase; Identified by match to protein family HMM PF01546; match to protein family HMM TIGR01879. (431 aa) |
| | ABK73966.1 | Conserved hypothetical protein; Identified by match to protein family HMM PF06187. (387 aa) |
| | metH | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1246 aa) |
| | ABK73785.1 | Peptidase M20; Identified by match to protein family HMM PF01546; match to protein family HMM PF07687. (444 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (364 aa) |
| | asnB-2 | Asparagine synthase (glutamine-hydrolyzing); Identified by match to protein family HMM PF00310; match to protein family HMM PF00733; match to protein family HMM TIGR01536. (658 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Catalyzes the reversible transfers of an amino group from glutamate to the alpha-ketoacid of the respective amino acid in the final step in the biosynthesis of branchedchain amino acids. The amino acids can be ranked in the following order with respect to their efficiency as amino donor: Leu > Ile > Val. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (368 aa) |
| | glnA-2 | Glutamine synthetase, type I; Involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. (478 aa) |
| | glnA-3 | Glutamine synthetase, type I; Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism. It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. Feedback- inhibited GlnA also interacts with and regulates the activity of the transcriptional regulator TnrA. During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation [...] (446 aa) |
| | ABK71359.1 | Acetolactate synthase large subunit; Identified by match to protein family HMM PF02775; match to protein family HMM PF02776. (518 aa) |
| | ABK74373.1 | Acetolactate synthase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. (540 aa) |
| | cysH | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (236 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (424 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (370 aa) |
| | ABK72686.1 | IolD protein; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. (649 aa) |
| | ABK74044.1 | Peptidase M20; Identified by match to protein family HMM PF01546; match to protein family HMM PF07687. (439 aa) |
| | cysM | Cysteine synthase B; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136. (323 aa) |
| | ABK74504.1 | Identified by match to protein family HMM PF02597. (93 aa) |
| | ABK73517.1 | Identified by match to protein family HMM PF01398. (138 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (317 aa) |
| | thrC | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (360 aa) |
| | ABK75362.1 | Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. (439 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (474 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls. (355 aa) |
| | dapD | Tetrahydropicolinate succinylase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (314 aa) |
| | ABK75653.1 | Aminotransferase class-III; Identified by match to protein family HMM PF00202; match to protein family HMM PF01636. (977 aa) |
| | ABK74143.1 | Riboflavin biosynthesis protein RibD C- domain protein; Identified by match to protein family HMM PF01872. (185 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (490 aa) |
| | ABK69767.1 | Putative cystathionine gamma-synthase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM PF01212. (384 aa) |
| | ABK75142.1 | Cystathionine beta-synthase; Identified by match to protein family HMM PF00291; match to protein family HMM PF00571; match to protein family HMM TIGR01137. (463 aa) |
| | dapB-6 | Dihydrodipicolinate reductase, N-terminus domain protein; Identified by match to protein family HMM PF01113. (349 aa) |
| | ABK75186.1 | oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. (576 aa) |
| | ABK76235.1 | Glutamate--ammonia ligase; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family. (477 aa) |
| | ABK70402.1 | LysA protein. (237 aa) |
| | ABK72054.1 | Glutamate dehydrogenase; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (449 aa) |
| | ABK73455.1 | Conserved hypothetical protein; Identified by match to protein family HMM PF01113; match to protein family HMM PF01408. (358 aa) |
| | serC | Phosphoserine aminotransferase, putative; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (370 aa) |
| | ABK69794.1 | PLP-dependent aminotransferases; Identified by match to protein family HMM PF00155; match to protein family HMM PF01212. (390 aa) |
| | ABK73595.1 | Pyruvate decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. (768 aa) |
| | cysE | Serine O-acetyltransferase. (172 aa) |
| | ABK72506.1 | Phosphoglycerate dehydrogenase; Identified by match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (334 aa) |
| | ABK71449.1 | Morphological differentiation-associated protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490. (293 aa) |
| | ABK74501.1 | Diaminopimelate decarboxylase; Identified by match to protein family HMM PF00278; match to protein family HMM PF02784. (459 aa) |
| | ABK74603.1 | Cysteine synthase/cystathionine beta-synthase family protein; Identified by match to protein family HMM PF00291. (365 aa) |
| | egtD | Conserved hypothetical protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine. Among all the proteinogenic amino acids, only L-histidine is a substrate. (321 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (346 aa) |
| | ABK73626.1 | Asparate kinase, monofunctional class; Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00656; match to protein family HMM TIGR00657; Belongs to the aspartokinase family. (421 aa) |
| | glnT | Glutamine synthetase, type III; Identified by match to protein family HMM PF00120; match to protein family HMM TIGR03105; Belongs to the glutamine synthetase family. (434 aa) |
| | ABK71222.1 | Glutamine amidotransferase, class II; Identified by match to protein family HMM PF00310. (289 aa) |
| | ABK76114.1 | Identified by match to protein family HMM PF01493. (231 aa) |
| | ABK73420.1 | Identified by match to protein family HMM PF01070; match to protein family HMM PF01180; match to protein family HMM PF01645; Belongs to the glutamate synthase family. (446 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (602 aa) |
| | ABK71789.1 | Prephenate dehydrogenase; Identified by match to protein family HMM PF02153. (314 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (417 aa) |
| | pheA | Prephenate dehydratase; Identified by match to protein family HMM PF00800; match to protein family HMM PF01842. (310 aa) |
| | GltD-2 | Glutamate synthase, small subunit; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01317. (488 aa) |
| | ABK70243.1 | Ferredoxin-dependent glutamate synthase 1; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. (1542 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (771 aa) |
| | ABK75399.1 | Glutamine synthetase III; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family. (461 aa) |
| | ABK70749.1 | Conserved hypothetical protein. (199 aa) |
| | leuC-2 | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (422 aa) |
| | leuD-2 | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (182 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (136 aa) |
| | ABK74591.1 | oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. (577 aa) |
| | ABK70568.1 | Acetyltransferase; Identified by match to protein family HMM PF00583. (158 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Identified by match to protein family HMM PF00920; match to protein family HMM TIGR00110; Belongs to the IlvD/Edd family. (571 aa) |
| | ABK69722.1 | Aminoglycoside phosphotransferase; Identified by match to protein family HMM PF01636. (334 aa) |
| | ABK72673.1 | Putative aminotransferase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (426 aa) |
| | edd | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (609 aa) |
| | Rv0926c | Conserved hypothetical protein; Identified by match to protein family HMM PF01113. (362 aa) |
| | ABK71627.1 | Dihydroxy-acid dehydratase; Identified by match to protein family HMM PF00920; Belongs to the IlvD/Edd family. (564 aa) |
| | dapB | Dihydrodipicolinate reductase, N-terminus domain protein; Identified by match to protein family HMM PF01113. (354 aa) |
| | ABK70809.1 | Glyoxylate reductase; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (322 aa) |
| | ABK73398.1 | Hypothetical protein; Identified by Glimmer2; putative. (180 aa) |
| | dapB-2 | Dihydrodipicolinate reductase, N-terminus domain protein; Identified by match to protein family HMM PF01113. (359 aa) |
| | metZ | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (405 aa) |
| | ABK69763.1 | Identified by match to protein family HMM PF01636. (368 aa) |
| | ABK74148.1 | N-carbamoyl-L-amino acid amidohydrolase; Identified by match to protein family HMM PF01546; match to protein family HMM TIGR01879. (419 aa) |
| | ABK72063.1 | Dihydrodipicolinate synthase; Identified by match to protein family HMM PF00701; Belongs to the DapA family. (310 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (286 aa) |
| | ABK74733.1 | HAD-superfamily protein subfamily protein IB hydrolase, TIGR01490; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490. (296 aa) |
| | mtaP | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (259 aa) |
| | ABK70080.1 | Acetyltransferase, gnat family protein, putative; Identified by match to protein family HMM PF00583. (285 aa) |
| | serB | Phosphoserine phosphatase; Identified by match to protein family HMM PF00702; match to protein family HMM PF01842; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488. (413 aa) |
| | ABK73788.1 | Integral membrane protein; Identified by match to protein family HMM PF02588. (231 aa) |
| | ABK71940.1 | Gamma-glutamylisopropylamide synthetase; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family. (450 aa) |
| | ABK75999.1 | Dihydrodipicolinate synthetase; Identified by match to protein family HMM PF00701; Belongs to the DapA family. (295 aa) |
| | ABK75573.1 | N-carbamoyl-L-amino acid hydrolase; Identified by match to protein family HMM PF01546; match to protein family HMM TIGR01879. (404 aa) |
| | ABK71016.1 | Prophage Lp1 protein 5; Identified by match to protein family HMM PF07553. (132 aa) |
| | ilvD-2 | Dihydroxy-acid dehydratase; Identified by match to protein family HMM PF00920; match to protein family HMM TIGR00110; Belongs to the IlvD/Edd family. (622 aa) |
| | rocD | Ornithine--oxo-acid transaminase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR01885; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (422 aa) |
| | ABK71806.1 | Acetolactate synthase; Identified by match to protein family HMM PF02775; match to protein family HMM PF02776. (576 aa) |
| | alr | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (389 aa) |
| | ABK72223.1 | Benzoylformate decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. (537 aa) |
| | folD | Tetrahydrofolate dehydrogenase/cyclohydrolase FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (283 aa) |
| | metX | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (380 aa) |
| | ABK72109.1 | O-acetylhomoserine sulfhydrylase; Identified by match to protein family HMM PF01053; match to protein family HMM PF01212; match to protein family HMM TIGR01326. (443 aa) |
| | ABK70791.1 | Amidohydrolase; Identified by match to protein family HMM PF01546; match to protein family HMM TIGR01891. (390 aa) |
| | mtnN | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (250 aa) |
| | ABK72773.1 | Conserved hypothetical protein. (71 aa) |
| | selD | Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (330 aa) |
| | ABK69677.1 | Molybdopterin biosynthesis protein MoeB; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237. (396 aa) |
| | ABK73961.1 | Conserved hypothetical protein; Identified by match to protein family HMM TIGR02569. (284 aa) |
| | ABK72975.1 | Tartrate dehydrogenase; Identified by similarity to SP:Q51945; match to protein family HMM PF00180; match to protein family HMM TIGR02089. (366 aa) |
| | ABK75903.1 | Identified by match to protein family HMM PF01546; match to protein family HMM PF07687. (443 aa) |
| | ABK70985.1 | Pyruvate dehydrogenase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. (576 aa) |
| | serB-2 | Phosphoserine phosphatase; Identified by match to protein family HMM PF00702; match to protein family HMM PF01842; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488. (413 aa) |
| | ABK69641.1 | Integral membrane protein; Identified by match to protein family HMM PF02588. (231 aa) |
| | ABK74802.1 | Methionine synthase, vitamin-B12 independent; Identified by match to protein family HMM PF01717. (336 aa) |
| | ilvB | Acetolactate synthase, large subunit, biosynthetic type; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118. (618 aa) |
| | ilvN | Acetolactate synthase, small subunit; Identified by match to protein family HMM PF01842; match to protein family HMM TIGR00119; Belongs to the acetolactate synthase small subunit family. (170 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (337 aa) |
| | serA | D-3-phosphoglycerate dehydrogenase; Identified by match to protein family HMM PF00389; match to protein family HMM PF01842; match to protein family HMM PF02826; match to protein family HMM TIGR01327; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (528 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (340 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (484 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (197 aa) |
| | ABK73212.1 | Putative cystathionine gamma-synthase; Identified by match to protein family HMM PF01053. (369 aa) |
| | ABK72556.1 | MarR-family protein transcriptional regulator; Identified by match to protein family HMM PF00583. (164 aa) |
| | ABK75619.1 | Acetylornithine deacetylase; Identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01910. (390 aa) |
| | ABK72227.1 | 3-isopropylmalate dehydratase small subunit; Identified by match to protein family HMM TIGR02087; Belongs to the LeuD family. (175 aa) |
| | ABK70728.1 | 3-isopropylmalate dehydratase large subunit; Identified by match to protein family HMM PF00330. (413 aa) |
| | asnB | Asparagine synthase (glutamine-hydrolyzing); Identified by match to protein family HMM PF00310; match to protein family HMM PF00733; match to protein family HMM TIGR01536; match to protein family HMM TIGR03104. (601 aa) |
| | ABK70552.1 | Gamma-glutamylisopropylamide synthetase; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family. (457 aa) |
| | ABK70503.1 | Conserved hypothetical protein; Identified by match to protein family HMM PF06187. (396 aa) |
| | dapB-3 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (245 aa) |
| | folA | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (154 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (300 aa) |
| | ABK72081.1 | Identified by match to protein family HMM PF00583; Belongs to the acetyltransferase family. (160 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (291 aa) |
| | ABK73071.1 | Integral membrane protein. (166 aa) |
| | carA | Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family. (382 aa) |
| | carB | Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02655; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369; Belongs to the CarB family. (1115 aa) |
| | ilvA | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (430 aa) |
| | priA-2 | Bifunctional HisA/TrpF protein; Involved in both the histidine and tryptophan biosynthetic pathways; Belongs to the HisA/HisF family. (258 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (524 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Identified by match to protein family HMM PF00218; Belongs to the TrpC family. (272 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (425 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (262 aa) |
| | ABK75308.1 | TM2 domain protein; Identified by match to protein family HMM PF05154. (95 aa) |
| | ABK70099.1 | Ferredoxin-dependent glutamate synthase 1; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. (1518 aa) |
| | GltD | Glutamate synthase, NADH/nadph, small subunit; Identified by match to protein family HMM PF01266; match to protein family HMM PF07992; match to protein family HMM TIGR01317. (500 aa) |
| | ABK72982.1 | 3-isopropylmalate dehydrogenase; Identified by match to protein family HMM PF00180. (356 aa) |
| | ABK72037.1 | Conserved hypothetical protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (433 aa) |
| | dapB-4 | Dihydrodipicolinate reductase, N-terminus domain protein; Identified by match to protein family HMM PF01113; match to protein family HMM PF01408; match to protein family HMM PF02629. (340 aa) |
| | ABK70807.1 | Putative acetolactate synthase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. (539 aa) |
| | ABK70335.1 | Acetylornithine deacetylase; Identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01910. (443 aa) |
| | ABK70798.1 | DNA-binding protein. (215 aa) |
| | ABK73577.1 | HAD-superfamily protein subfamily protein IB hydrolase; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490. (223 aa) |
| | ABK71282.1 | Identified by match to protein family HMM PF00291. (316 aa) |
| | glnA | Glutamine synthetase, catalytic domain; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family. (453 aa) |
| | argH | Argininosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00838. (469 aa) |
| | argG | Argininosuccinate synthase; Identified by match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (399 aa) |
| | argR | Arginine repressor; Regulates arginine biosynthesis genes. (158 aa) |
| | argF | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (307 aa) |
| | argD | Acetylornithine aminotransferase; Identified by match to protein family HMM PF00202; match to protein family HMM PF01212; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (390 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (293 aa) |
