STRINGSTRING
ABK70393.1 ABK70393.1 ABK70982.1 ABK70982.1 ABK76236.1 ABK76236.1 ABK71257.1 ABK71257.1 ABK72268.1 ABK72268.1 ABK75575.1 ABK75575.1 ABK75525.1 ABK75525.1 ABK75053.1 ABK75053.1 ABK74259.1 ABK74259.1 ABK70745.1 ABK70745.1 ABK72769.1 ABK72769.1 ethA ethA ABK73229.1 ABK73229.1 ABK70327.1 ABK70327.1 ABK70572.1 ABK70572.1 katA-2 katA-2 ABK72340.1 ABK72340.1 ABK71916.1 ABK71916.1 ABK72517.1 ABK72517.1 ABK72507.1 ABK72507.1 ABK73948.1 ABK73948.1 ABK74809.1 ABK74809.1 metN-2 metN-2 ABK72942.1 ABK72942.1 ABK75856.1 ABK75856.1 ABK71229.1 ABK71229.1 ABK71970.1 ABK71970.1 ABK71973.1 ABK71973.1 ABK72828.1 ABK72828.1 ABK70606.1 ABK70606.1 ABK70122.1 ABK70122.1 ABK71554.1 ABK71554.1 ABK75144.1 ABK75144.1 ABK72062.1 ABK72062.1 ABK76006.1 ABK76006.1 ABK70326.1 ABK70326.1 ABK74000.1 ABK74000.1 ABK74987.1 ABK74987.1 ABK75773.1 ABK75773.1 orB orB ssuD-7 ssuD-7 ssuD-6 ssuD-6 ABK71667.1 ABK71667.1 ABK70028.1 ABK70028.1 ABK75915.1 ABK75915.1 ABK75988.1 ABK75988.1 ABK75700.1 ABK75700.1 ABK72867.1 ABK72867.1 ABK74121.1 ABK74121.1 ABK75872.1 ABK75872.1 ABK71744.1 ABK71744.1 ssuD-5 ssuD-5 ABK76152.1 ABK76152.1 ABK73275.1 ABK73275.1 ssuD-4 ssuD-4 ABK69647.1 ABK69647.1 ABK72493.1 ABK72493.1 ABK73619.1 ABK73619.1 ABK73964.1 ABK73964.1 ABK71322.1 ABK71322.1 ABK70686.1 ABK70686.1 ABK72297.1 ABK72297.1 glcB glcB ABK75146.1 ABK75146.1 ABK70230.1 ABK70230.1 ABK73565.1 ABK73565.1 ABK71848.1 ABK71848.1 ABK75607.1 ABK75607.1 katA katA tpx tpx ABK72595.1 ABK72595.1 ABK70624.1 ABK70624.1 ABK75759.1 ABK75759.1 ABK69613.1 ABK69613.1 metN metN ABK74167.1 ABK74167.1 ABK75450.1 ABK75450.1 ABK71769.1 ABK71769.1 relA relA pgsA-2 pgsA-2 ABK69720.1 ABK69720.1 ABK71452.1 ABK71452.1 ABK73330.1 ABK73330.1 ABK69687.1 ABK69687.1 ABK73624.1 ABK73624.1 ssuD-2 ssuD-2 ssuD ssuD ABK74993.1 ABK74993.1 ABK73270.1 ABK73270.1 sigA sigA pgsA pgsA ABK73814.1 ABK73814.1 ABK73845.1 ABK73845.1 ABK73664.1 ABK73664.1 ABK72224.1 ABK72224.1 mutM mutM ABK75646.1 ABK75646.1 ABK72991.1 ABK72991.1 ABK70844.1 ABK70844.1 ABK70514.1 ABK70514.1 ABK69576.1 ABK69576.1 ABK74594.1 ABK74594.1 ABK70857.1 ABK70857.1 nuoG nuoG ABK71963.1 ABK71963.1 ABK71939.1 ABK71939.1 ABK70504.1 ABK70504.1 ABK71537.1 ABK71537.1 ABK73168.1 ABK73168.1 ABK74586.1 ABK74586.1 ABK71318.1 ABK71318.1 ABK75024.1 ABK75024.1 ABK73428.1 ABK73428.1 ABK74515.1 ABK74515.1 ABK69784.1 ABK69784.1 ABK71598.1 ABK71598.1 ABK75757.1 ABK75757.1 ABK73458.1 ABK73458.1 ABK75115.1 ABK75115.1 ABK75501.1 ABK75501.1 ABK74229.1 ABK74229.1 mspA mspA ABK73210.1 ABK73210.1 fgd fgd ABK74466.1 ABK74466.1 dnaK dnaK ABK72261.1 ABK72261.1 ABK75774.1 ABK75774.1 ABK70539.1 ABK70539.1 ABK73257.1 ABK73257.1 ABK71946.1 ABK71946.1 ABK71316.1 ABK71316.1 ABK70757.1 ABK70757.1 ABK75025.1 ABK75025.1 ABK72335.1 ABK72335.1 ABK73410.1 ABK73410.1 ABK72130.1 ABK72130.1 ABK75609.1 ABK75609.1 ABK74488.1 ABK74488.1 esxA esxA panD panD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABK70393.1Identified by match to protein family HMM PF01266. (519 aa)
ABK70982.1MmcI protein. (257 aa)
ABK76236.1MmcI protein. (274 aa)
ABK71257.1Dibenzothiophene desulfurization enzyme A. (437 aa)
ABK72268.1N5,N10- methylenetetrahydromethanopterin reductase-related protein. (276 aa)
ABK75575.1Nitrilotriacetate monooxygenase component A. (453 aa)
ABK75525.1Identified by match to protein family HMM PF00296. (283 aa)
ABK75053.1Oxidoreductase; Identified by match to protein family HMM PF00296. (345 aa)
ABK74259.1Identified by match to protein family HMM PF00300. (235 aa)
ABK70745.1Virulence factor Mce family protein; Identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996. (413 aa)
ABK72769.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (284 aa)
ethAMonooxygenase, flavin-binding family protein; Monooxygenase able to convert a wide range of ketones to the corresponding esters or lactones via a Baeyer-Villiger oxidation reaction. Can act on long-chain aliphatic ketones (2-hexanone to 2- dodecanone) and on aromatic ketones (phenylacetone and benzylacetone). Is also able to catalyze enantioselective sulfoxidation of methyl-p- tolylsulfide. In vivo, likely functions as a BVMO, but the exact nature of the physiological substrate(s) remains to be established. (492 aa)
ABK73229.1Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family. (228 aa)
ABK70327.1Conserved hypothetical protein. (337 aa)
ABK70572.1Phosphoglycerate mutase family protein, putative; Identified by match to protein family HMM PF00300. (202 aa)
katA-2Catalase KatA; Identified by similarity to SP:P26901; match to protein family HMM PF00199. (553 aa)
ABK72340.1Limonene 1,2-monooxygenase; Identified by match to protein family HMM PF00296. (395 aa)
ABK71916.1Conserved hypothetical protein; Identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026. (159 aa)
ABK72517.1FMN-dependent monooxygenase; Identified by match to protein family HMM PF00296. (343 aa)
ABK72507.1Virulence factor Mce family protein; Identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996. (400 aa)
ABK73948.1Virulence factor Mce family protein; Identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996. (404 aa)
ABK74809.1Putative monooxygenase. (469 aa)
metN-2D-methionine transport ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (315 aa)
ABK72942.1Monooxygenase; Identified by match to protein family HMM PF00296. (306 aa)
ABK75856.1Identified by match to protein family HMM PF01522. (299 aa)
ABK71229.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (330 aa)
ABK71970.1Identified by match to protein family HMM PF01061; match to protein family HMM TIGR03061; match to protein family HMM TIGR03062. (668 aa)
ABK71973.1Luciferase; Identified by match to protein family HMM PF00296. (390 aa)
ABK72828.1Conserved hypothetical protein. (273 aa)
ABK70606.1formamidopyrimidine-DNA glycosylase; Identified by match to protein family HMM PF01149; match to protein family HMM PF06831; Belongs to the FPG family. (288 aa)
ABK70122.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (282 aa)
ABK71554.1Monooxygenase; Identified by match to protein family HMM PF00296. (376 aa)
ABK75144.1Alkanal monooxygenase alpha chain; Identified by match to protein family HMM PF00296. (349 aa)
ABK72062.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (293 aa)
ABK76006.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (318 aa)
ABK70326.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (436 aa)
ABK74000.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (303 aa)
ABK74987.1Virulence factor; Identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996. (424 aa)
ABK75773.1Putative formamidopyrimidine-DNA glycosylase; Identified by match to protein family HMM PF01149; match to protein family HMM PF06831; Belongs to the FPG family. (268 aa)
orBAlpha oxoglutarate ferredoxin oxidoreductase, beta subunit; Identified by match to protein family HMM PF02775. (342 aa)
ssuD-7Nitrilotriacetate monooxygenase component A. (445 aa)
ssuD-6Nitrilotriacetate monooxygenase component A; Identified by match to protein family HMM PF00296. (434 aa)
ABK71667.1Monoxygenase. (460 aa)
ABK70028.1Alkanesulfonate monooxygenase. (368 aa)
ABK75915.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (317 aa)
ABK75988.1Monooxygenase, NtaA/SnaA/SoxA family protein. (456 aa)
ABK75700.1Polysaccharide deacetylase, putative; Identified by match to protein family HMM PF01522. (297 aa)
ABK72867.1Conserved hypothetical proline rich protein. (592 aa)
ABK74121.1Conserved hypothetical protein. (295 aa)
ABK75872.1Identified by match to protein family HMM PF01522. (283 aa)
ABK71744.1Alkanesulfonate monooxygenase; Identified by match to protein family HMM PF00296. (362 aa)
ssuD-5Nitrilotriacetate monooxygenase component A. (411 aa)
ABK76152.1Putative monooxygenase. (305 aa)
ABK73275.1Alkanal monooxygenase; Identified by match to protein family HMM PF00296. (356 aa)
ssuD-4Nitrilotriacetate monooxygenase component A. (444 aa)
ABK69647.1Nitrilotriacetate monooxygenase component A. (427 aa)
ABK72493.1Putative monooxygenase. (471 aa)
ABK73619.1Monoxygenase. (448 aa)
ABK73964.1Oxidoreductase; Identified by match to protein family HMM PF00296. (339 aa)
ABK71322.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (284 aa)
ABK70686.1Identified by similarity to GB:AAB82564.1; match to protein family HMM PF00296. (368 aa)
ABK72297.1Conserved hypothetical protein. (267 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (721 aa)
ABK75146.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (309 aa)
ABK70230.1Hydride transferase 1; Identified by match to protein family HMM PF00296. (327 aa)
ABK73565.1Monooxygenase; Identified by match to protein family HMM PF00296. (334 aa)
ABK71848.1N5,N10-methylene- tetrahydromethanopterin reductase; Identified by match to protein family HMM PF00296. (339 aa)
ABK75607.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (301 aa)
katACatalase KatA; Identified by similarity to SP:P26901; match to protein family HMM PF00199. (485 aa)
tpxThiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (164 aa)
ABK72595.15,10-methylenetetrahydromethanopterin reductase; Identified by match to protein family HMM PF00296. (337 aa)
ABK70624.1Identified by match to protein family HMM PF01522. (288 aa)
ABK75759.1Conserved hypothetical protein TIGR00026; Identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026. (112 aa)
ABK69613.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (286 aa)
metNABC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (331 aa)
ABK74167.1Conserved hypothetical protein TIGR00026; Identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026. (151 aa)
ABK75450.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (284 aa)
ABK71769.1Polysaccharide deacetylase; Identified by match to protein family HMM PF01522. (288 aa)
relAGTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (797 aa)
pgsA-2Phosphatidylinositol synthase; Catalyzes the conjugation of the 1'-hydroxyl group of D-myo- inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid for mycobacteria required for formation of their cell wall. Is essential to the survival of M.smegmatis. Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (222 aa)
ABK69720.1Conserved hypothetical protein. (274 aa)
ABK71452.1MmcI protein. (130 aa)
ABK73330.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (287 aa)
ABK69687.1Virulence factor Mce family protein; Identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996. (395 aa)
ABK73624.1Identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026. (140 aa)
ssuD-2Nitrilotriacetate monooxygenase component A. (451 aa)
ssuDNitrilotriacetate monooxygenase component A. (431 aa)
ABK74993.1Putative monooxygenase. (481 aa)
ABK73270.1Hydride transferase 1; Identified by match to protein family HMM PF00296. (288 aa)
sigASigma factor MysA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (466 aa)
pgsACDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (201 aa)
ABK73814.1Alkanesulfonate monooxygenase family protein; Identified by similarity to SP:P40402. (385 aa)
ABK73845.1Hypothetical protein; Identified by Glimmer2; putative. (79 aa)
ABK73664.1Putative oxidoreductase; Identified by match to protein family HMM PF00296. (309 aa)
ABK72224.15,10-methylenetetrahydromethanopterin reductase; Identified by match to protein family HMM PF00296. (332 aa)
mutMformamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Acts on oxidized purines, such as 7,8-dihydro-8- oxoguanine (8-oxoG) when paired with C, G or T. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates; Belongs to the FPG family. (285 aa)
ABK75646.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (292 aa)
ABK72991.1Conserved hypothetical protein. (350 aa)
ABK70844.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (376 aa)
ABK70514.1Fmnh2-utilizing oxygenase. (392 aa)
ABK69576.1Nitrilotriacetate monooxygenase component A. (458 aa)
ABK74594.1MmcJ protein. (279 aa)
ABK70857.15,10-methylenetetrahydromethanopterin reductase. (299 aa)
nuoGNADH-quinone oxidoreductase, G subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (794 aa)
ABK71963.1Monoxygenase; Identified by match to protein family HMM PF00296. (454 aa)
ABK71939.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (329 aa)
ABK70504.1N5,N10- methylenetetrahydromethanopterin reductase-related protein; Identified by match to protein family HMM PF00296. (287 aa)
ABK71537.1Valosin containing protein-1; Identified by match to protein family HMM PF00004; Belongs to the AAA ATPase family. (401 aa)
ABK73168.1Dehydrogenase; Identified by match to protein family HMM PF00296. (335 aa)
ABK74586.1Endonuclease VIII and dna n-glycosylase with an ap lyase activity; Identified by match to protein family HMM PF01149; match to protein family HMM PF06827; match to protein family HMM PF06831; Belongs to the FPG family. (252 aa)
ABK71318.1Putative monooxygenase. (293 aa)
ABK75024.1Oxidoreductase; Identified by match to protein family HMM PF00296. (347 aa)
ABK73428.1Conserved hypothetical protein. (368 aa)
ABK74515.1Conserved hypothetical protein. (298 aa)
ABK69784.1Conserved hypothetical protein. (283 aa)
ABK71598.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (326 aa)
ABK75757.1Identified by match to protein family HMM PF01522. (303 aa)
ABK73458.1Nitrilotriacetate monooxygenase component A. (448 aa)
ABK75115.1Mce related protein; Identified by match to protein family HMM PF02470. (534 aa)
ABK75501.1Polysaccharide deacetylase; Identified by match to protein family HMM PF01522. (287 aa)
ABK74229.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (292 aa)
mspAPorin; The major porin in this organism, forms a water-filled channel which favors the permeation of cations, amino acids, iron Fe(3+) and less efficiently phosphate. Does not transport Fe-ExoMS, the predominant siderophore. Plays a role in transport of beta-lactamase and hydrophilic fluoroquinolone antibiotics such as norfloxacin as well as chloramphenicol. There are about 2400 porins in wild-type, 800 in an mspA deletion and 150 in a double mspA-mspC deletion. Different conductance values with maxima at 2.3 and 4.6 nanosiemens might be caused by a simultaneous reconstitution of MspA [...] (211 aa)
ABK73210.1Cell division control protein Cdc48; Identified by match to protein family HMM PF00004; match to protein family HMM PF02359; Belongs to the AAA ATPase family. (745 aa)
fgdF420-dependent glucose-6-phosphate dehydrogenase; Catalyzes the coenzyme F420-dependent oxidation of glucose 6- phosphate (G6P) to 6-phosphogluconolactone. Appears to have a role in resistance to oxidative stress, via its consumption of G6P that serves as a source of reducing power to combat oxidative stress in mycobacteria. Cannot use NAD, NADP, FAD or FMN instead of coenzyme F420 as an electron acceptor. Exhibits nearly no activity with D-mannose-6- phosphate or D-fructose-6-phosphate as substrate. Belongs to the F420-dependent glucose-6-phosphate dehydrogenase family. (337 aa)
ABK74466.1Conserved hypothetical protein. (302 aa)
dnaKChaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (622 aa)
ABK72261.1Monooxygenase; Identified by match to protein family HMM PF00296. (310 aa)
ABK75774.1Conserved hypothetical proline rich protein. (616 aa)
ABK70539.1Conserved hypothetical protein. (595 aa)
ABK73257.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (311 aa)
ABK71946.1Conserved hypothetical proline and threonine rich protein. (643 aa)
ABK71316.1Probable serine/threonine-protein kinase PknK; Identified by match to protein family HMM PF00069; match to protein family HMM PF07721. (1148 aa)
ABK70757.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (308 aa)
ABK75025.1Identified by match to protein family HMM PF00011; Belongs to the small heat shock protein (HSP20) family. (145 aa)
ABK72335.1Virulence factor; Identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996. (474 aa)
ABK73410.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (338 aa)
ABK72130.1FMN-dependent monooxygenase; Identified by match to protein family HMM PF00296. (338 aa)
ABK75609.1Putative dehydrogenase; Identified by match to protein family HMM PF00296. (298 aa)
ABK74488.1Virulence factor Mce family protein; Identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996. (409 aa)
esxAEarly secretory antigenic target, 6 kDa; An exported protein. Unlike its M.tuberculosis counterpart has poor pore forming ability in artificial liposomes, does not undergo conformational change at acidic pH. Mutation of 2 residues to those found in M.tuberculosis (25-TA-26 to IH) alters the properties of this protein so that it inserts into liposomes at acidic pH, forming pores, like its M.tuberculosis counterpart. (95 aa)
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (136 aa)
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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