24 items (Mycolicibacterium smegmatis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ABK73556.1	ABC-2 type transporter superfamily protein; Identified by match to protein family HMM PF01061. (280 aa)
	ABK71286.1	RsbW protein. (194 aa)
	ABK73168.1	Dehydrogenase; Identified by match to protein family HMM PF00296. (335 aa)
	ABK71220.1	RsbW protein. (138 aa)
	sigH	RNA polymerase sigma-70 factor, family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by an anti-sigma factor until released. This sigma factor is involved in heat shock and oxidative stress responses. (219 aa)
	whiB	Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (84 aa)
	ABK73010.1	Identified by match to protein family HMM PF00857. (201 aa)
	ABK71699.1	Dihydrokaempferol 4-reductase; Identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993. (339 aa)
	ABK74949.1	Phytoene dehydrogenase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01593; match to protein family HMM TIGR02734. (517 aa)
	katG	Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. May play a role in the intracellular survival of mycobacteria. (748 aa)
	katA	Catalase KatA; Identified by similarity to SP:P26901; match to protein family HMM PF00199. (485 aa)
	katG-2	Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (688 aa)
	ABK71569.1	Transcriptional regulator; Identified by match to protein family HMM PF00440. (196 aa)
	ABK72625.1	Dehydrogenase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01593. (530 aa)
	ABK70329.1	Dehydrogenase DhgA; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370. (262 aa)
	ABK75651.1	Transcriptional regulator, HTH_3 family protein; Identified by match to protein family HMM PF01381. (93 aa)
	ABK70412.1	Transcriptional regulator, GntR family protein; Identified by match to protein family HMM PF00392; match to protein family HMM PF07729. (231 aa)
	phoP	DNA-binding response regulator PhoP; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. (239 aa)
	ABK75922.1	Manganese containing catalase; Identified by match to protein family HMM PF05067. (297 aa)
	katA-2	Catalase KatA; Identified by similarity to SP:P26901; match to protein family HMM PF00199. (553 aa)
	katG-3	Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. May play a role in the intracellular survival of mycobacteria. (739 aa)
	dps	Starvation-induced DNA protecting protein; Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction (By similarity). It protects DNA from hydroxyl radical-mediated cleavage. Binds DNA with no apparent sequence specificity without self- aggregation nor promotion of DNA condensation. Is unable to protect DNA from DNase-mediated cleavage (By similarity). (183 aa)
	ABK71759.1	MarR-family protein transcriptional regulator; Identified by match to protein family HMM PF01047; match to protein family HMM PF03965. (155 aa)
	ABK70529.1	Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801. (1826 aa)

Your Current Organism:

Mycolicibacterium smegmatis

NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABK70329.1	ABK70529.1	MSMEG_5402	MSMEG_6767	Dehydrogenase DhgA; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370.	Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801.	0.400
ABK70329.1	ABK71699.1	MSMEG_5402	MSMEG_2247	Dehydrogenase DhgA; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370.	Dihydrokaempferol 4-reductase; Identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993.	0.453
ABK70329.1	ABK72625.1	MSMEG_5402	MSMEG_5400	Dehydrogenase DhgA; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370.	Dehydrogenase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01593.	0.953
ABK70329.1	ABK73168.1	MSMEG_5402	MSMEG_1794	Dehydrogenase DhgA; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370.	Dehydrogenase; Identified by match to protein family HMM PF00296.	0.797
ABK70329.1	ABK75922.1	MSMEG_5402	MSMEG_6213	Dehydrogenase DhgA; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370.	Manganese containing catalase; Identified by match to protein family HMM PF05067.	0.773
ABK70329.1	dps	MSMEG_5402	MSMEG_6467	Dehydrogenase DhgA; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370.	Starvation-induced DNA protecting protein; Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction (By similarity). It protects DNA from hydroxyl radical-mediated cleavage. Binds DNA with no apparent sequence specificity without self- aggregation nor promotion of DNA condensation. Is unable to protect DNA from DNase-mediated cleavage (By similarity).	0.606
ABK70329.1	katA-2	MSMEG_5402	MSMEG_6232	Dehydrogenase DhgA; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370.	Catalase KatA; Identified by similarity to SP:P26901; match to protein family HMM PF00199.	0.554
ABK70412.1	ABK71569.1	MSMEG_5731	MSMEG_5301	Transcriptional regulator, GntR family protein; Identified by match to protein family HMM PF00392; match to protein family HMM PF07729.	Transcriptional regulator; Identified by match to protein family HMM PF00440.	0.817
ABK70412.1	ABK71759.1	MSMEG_5731	MSMEG_6508	Transcriptional regulator, GntR family protein; Identified by match to protein family HMM PF00392; match to protein family HMM PF07729.	MarR-family protein transcriptional regulator; Identified by match to protein family HMM PF01047; match to protein family HMM PF03965.	0.822
ABK70412.1	ABK75651.1	MSMEG_5731	MSMEG_5542	Transcriptional regulator, GntR family protein; Identified by match to protein family HMM PF00392; match to protein family HMM PF07729.	Transcriptional regulator, HTH_3 family protein; Identified by match to protein family HMM PF01381.	0.816
ABK70412.1	whiB	MSMEG_5731	MSMEG_1919	Transcriptional regulator, GntR family protein; Identified by match to protein family HMM PF00392; match to protein family HMM PF07729.	Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.	0.587
ABK70529.1	ABK70329.1	MSMEG_6767	MSMEG_5402	Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801.	Dehydrogenase DhgA; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370.	0.400
ABK70529.1	ABK71699.1	MSMEG_6767	MSMEG_2247	Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801.	Dihydrokaempferol 4-reductase; Identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993.	0.437
ABK70529.1	ABK73010.1	MSMEG_6767	MSMEG_2243	Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801.	Identified by match to protein family HMM PF00857.	0.411
ABK70529.1	ABK73556.1	MSMEG_6767	MSMEG_6765	Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801.	ABC-2 type transporter superfamily protein; Identified by match to protein family HMM PF01061.	0.922
ABK70529.1	katA	MSMEG_6767	MSMEG_3486	Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801.	Catalase KatA; Identified by similarity to SP:P26901; match to protein family HMM PF00199.	0.488
ABK70529.1	katA-2	MSMEG_6767	MSMEG_6232	Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801.	Catalase KatA; Identified by similarity to SP:P26901; match to protein family HMM PF00199.	0.496
ABK71569.1	ABK70412.1	MSMEG_5301	MSMEG_5731	Transcriptional regulator; Identified by match to protein family HMM PF00440.	Transcriptional regulator, GntR family protein; Identified by match to protein family HMM PF00392; match to protein family HMM PF07729.	0.817
ABK71569.1	ABK71759.1	MSMEG_5301	MSMEG_6508	Transcriptional regulator; Identified by match to protein family HMM PF00440.	MarR-family protein transcriptional regulator; Identified by match to protein family HMM PF01047; match to protein family HMM PF03965.	0.814
ABK71569.1	ABK75651.1	MSMEG_5301	MSMEG_5542	Transcriptional regulator; Identified by match to protein family HMM PF00440.	Transcriptional regulator, HTH_3 family protein; Identified by match to protein family HMM PF01381.	0.823